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Article: Postnatal development of nicotinamide adenine dinucleotide phosphate-diaphorase-positive neurons in the retina of the golden hamster

TitlePostnatal development of nicotinamide adenine dinucleotide phosphate-diaphorase-positive neurons in the retina of the golden hamster
Authors
Issue Date2002
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/31248
Citation
Journal Of Comparative Neurology, 2002, v. 446 n. 4, p. 342-348 How to Cite?
AbstractThe histochemical method was used to investigate the postnatal development of nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d)-positive neurons in retinas of the golden hamster. NADPH-d-positive neurons were discernible in the retina at postnatal day (P)1. From P4 onward to adulthood, when the retina acquired its laminated characteristics, NADPH-d-positive neurons were observed in the inner nuclear layer (INL) and the ganglion cell layer (GCL). Results showed that NADPH-d-positive neurons in INL and GCL followed different time courses and patterns in their development. NADPH-d-positive neurons in INL underwent a sharp increase from P4 to P8 (3.6-fold), followed by a decrease to 46% of the maximum at P12. This value was maintained relatively constant to the adult level. The mean diameters of NADPH-d-positive neurons in INL, which were smaller than those in the GCL for all ages, increased from P8 to P12 and from P20 to adulthood. As for neurons in the GCL, the increase in cell number was not so apparent for the earlier postnatal days until P20; thereafter, an obvious increase to the adult level was observed. The mean diameters of the NADPH-d-positive cell bodies in the GCL increased with age, except for P16-P20, during which time there was a slight and insignificant decrease. The tendency of changes in cell density was basically similar to that of the total number for both the INL and the GCL. Between P12 and P20, the density distribution map of the NADPH-d-positive neurons underwent dramatic changes: The highest density shifted from the upper central retina at the earlier postnatal days to the lower central retina in the adult. The two waves of increase in NADPH-d-positive neurons coincide with the process of axonal elongation and synaptogenesis and the acquisition of visual function and experience. It is suggested that these NADPH-d-positive neurons are related to these two developmental events. © 2002 Wiley-Liss, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/67837
ISSN
2015 Impact Factor: 3.331
2015 SCImago Journal Rankings: 2.345
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTay, Den_HK
dc.contributor.authorDiao, YCen_HK
dc.contributor.authorXiao, YMen_HK
dc.contributor.authorSo, KFen_HK
dc.date.accessioned2010-09-06T05:58:42Z-
dc.date.available2010-09-06T05:58:42Z-
dc.date.issued2002en_HK
dc.identifier.citationJournal Of Comparative Neurology, 2002, v. 446 n. 4, p. 342-348en_HK
dc.identifier.issn0021-9967en_HK
dc.identifier.urihttp://hdl.handle.net/10722/67837-
dc.description.abstractThe histochemical method was used to investigate the postnatal development of nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d)-positive neurons in retinas of the golden hamster. NADPH-d-positive neurons were discernible in the retina at postnatal day (P)1. From P4 onward to adulthood, when the retina acquired its laminated characteristics, NADPH-d-positive neurons were observed in the inner nuclear layer (INL) and the ganglion cell layer (GCL). Results showed that NADPH-d-positive neurons in INL and GCL followed different time courses and patterns in their development. NADPH-d-positive neurons in INL underwent a sharp increase from P4 to P8 (3.6-fold), followed by a decrease to 46% of the maximum at P12. This value was maintained relatively constant to the adult level. The mean diameters of NADPH-d-positive neurons in INL, which were smaller than those in the GCL for all ages, increased from P8 to P12 and from P20 to adulthood. As for neurons in the GCL, the increase in cell number was not so apparent for the earlier postnatal days until P20; thereafter, an obvious increase to the adult level was observed. The mean diameters of the NADPH-d-positive cell bodies in the GCL increased with age, except for P16-P20, during which time there was a slight and insignificant decrease. The tendency of changes in cell density was basically similar to that of the total number for both the INL and the GCL. Between P12 and P20, the density distribution map of the NADPH-d-positive neurons underwent dramatic changes: The highest density shifted from the upper central retina at the earlier postnatal days to the lower central retina in the adult. The two waves of increase in NADPH-d-positive neurons coincide with the process of axonal elongation and synaptogenesis and the acquisition of visual function and experience. It is suggested that these NADPH-d-positive neurons are related to these two developmental events. © 2002 Wiley-Liss, Inc.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/31248en_HK
dc.relation.ispartofJournal of Comparative Neurologyen_HK
dc.rightsThe Journal of Comparative Neurology. Copyright © John Wiley & Sons, Inc.en_HK
dc.subject.meshAging - metabolismen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshCell Differentiation - physiologyen_HK
dc.subject.meshCell Size - physiologyen_HK
dc.subject.meshCricetinaeen_HK
dc.subject.meshDendrites - enzymology - ultrastructureen_HK
dc.subject.meshMesocricetus - growth & development - metabolismen_HK
dc.subject.meshNADPH Dehydrogenase - metabolismen_HK
dc.subject.meshNitrergic Neurons - cytology - enzymologyen_HK
dc.subject.meshNitric Oxide - metabolismen_HK
dc.subject.meshNitric Oxide Synthase - metabolismen_HK
dc.subject.meshRetina - cytology - enzymology - growth & developmenten_HK
dc.titlePostnatal development of nicotinamide adenine dinucleotide phosphate-diaphorase-positive neurons in the retina of the golden hamsteren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9967&volume=446&spage=342&epage=348&date=2002&atitle=Postnatal+development+of+nicotinamide+adenine+dinucleotide+phosphate-diaphorase-positive+neurons+in+the+retina+of+the+golden+hamsteren_HK
dc.identifier.emailTay, D:dkctay@hkucc.hku.hken_HK
dc.identifier.emailSo, KF:hrmaskf@hkucc.hku.hken_HK
dc.identifier.authorityTay, D=rp00336en_HK
dc.identifier.authoritySo, KF=rp00329en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/cne.10201en_HK
dc.identifier.pmid11954033-
dc.identifier.scopuseid_2-s2.0-0036537038en_HK
dc.identifier.hkuros65846en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036537038&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume446en_HK
dc.identifier.issue4en_HK
dc.identifier.spage342en_HK
dc.identifier.epage348en_HK
dc.identifier.isiWOS:000174966300003-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTay, D=7006796825en_HK
dc.identifier.scopusauthoridDiao, YC=7004284577en_HK
dc.identifier.scopusauthoridXiao, YM=7403260801en_HK
dc.identifier.scopusauthoridSo, KF=34668391300en_HK

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