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Article: Exhaled nitric oxide: The effects of age, gender and body size

TitleExhaled nitric oxide: The effects of age, gender and body size
Authors
KeywordsAging
Body mass index
Body surface area
Exhaled nitric oxide
Gender
Issue Date2001
PublisherSpringer New York LLC. The Journal's web site is located at http://link.springer.de/link/service/journals/00408/
Citation
Lung, 2001, v. 179 n. 2, p. 83-91 How to Cite?
AbstractSince little is known of the effects of age, gender, and body size on exhaled nitric oxide (NO) production, we have conducted a prospective study to examine these factors in a healthy nonsmoking women (mean age ± SD 47.7 ± 15.8, range 20-79 years). Exhaled NO was measured by an automatic chemiluminescence analyzer (Sievers NO Analyser 280) at steady expiration. Men had significantly higher exhaled NO levels than women (p = 0.001). Although exhaled NO levels did not correlate with age (r = 0.12, p = 0.17), it correlated significantly with height (r = 0.23, p = 0.02), weight (r = 0.34, p < 0.001), body mass index (r = 0.25, p = 0.009), and body surface area (r = 0.42, p < 0.001) for the entire cohort. After making adjustment for age, height, weight, body mass index, and body surface area, exhaled NO levels were still significantly higher for men than for women (p = 0.004). Our data, therefore, could help explain the discrepancy in results of previous studies on exhaled NO production, which had not taken these parameters into account. Our findings should help researchers design future studies on evaluation of exhaled NO levels.
Persistent Identifierhttp://hdl.handle.net/10722/67826
ISSN
2015 Impact Factor: 2.0
2015 SCImago Journal Rankings: 0.785
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTsang, KWen_HK
dc.contributor.authorIp, SKen_HK
dc.contributor.authorLeung, Ren_HK
dc.contributor.authorTipoe, GLen_HK
dc.contributor.authorChan, SLen_HK
dc.contributor.authorShum, IHen_HK
dc.contributor.authorIp, MSen_HK
dc.contributor.authorYan, Cen_HK
dc.contributor.authorFung, PCen_HK
dc.contributor.authorChanYeung, Men_HK
dc.contributor.authorLam, Wen_HK
dc.date.accessioned2010-09-06T05:58:36Z-
dc.date.available2010-09-06T05:58:36Z-
dc.date.issued2001en_HK
dc.identifier.citationLung, 2001, v. 179 n. 2, p. 83-91en_HK
dc.identifier.issn0341-2040en_HK
dc.identifier.urihttp://hdl.handle.net/10722/67826-
dc.description.abstractSince little is known of the effects of age, gender, and body size on exhaled nitric oxide (NO) production, we have conducted a prospective study to examine these factors in a healthy nonsmoking women (mean age ± SD 47.7 ± 15.8, range 20-79 years). Exhaled NO was measured by an automatic chemiluminescence analyzer (Sievers NO Analyser 280) at steady expiration. Men had significantly higher exhaled NO levels than women (p = 0.001). Although exhaled NO levels did not correlate with age (r = 0.12, p = 0.17), it correlated significantly with height (r = 0.23, p = 0.02), weight (r = 0.34, p < 0.001), body mass index (r = 0.25, p = 0.009), and body surface area (r = 0.42, p < 0.001) for the entire cohort. After making adjustment for age, height, weight, body mass index, and body surface area, exhaled NO levels were still significantly higher for men than for women (p = 0.004). Our data, therefore, could help explain the discrepancy in results of previous studies on exhaled NO production, which had not taken these parameters into account. Our findings should help researchers design future studies on evaluation of exhaled NO levels.en_HK
dc.languageengen_HK
dc.publisherSpringer New York LLC. The Journal's web site is located at http://link.springer.de/link/service/journals/00408/en_HK
dc.relation.ispartofLungen_HK
dc.subjectAgingen_HK
dc.subjectBody mass indexen_HK
dc.subjectBody surface areaen_HK
dc.subjectExhaled nitric oxideen_HK
dc.subjectGenderen_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAging - metabolismen_HK
dc.subject.meshBody Constitutionen_HK
dc.subject.meshBody Mass Indexen_HK
dc.subject.meshBody Surface Areaen_HK
dc.subject.meshBreath Tests - instrumentationen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLuminescent Measurementsen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNitric Oxide - analysisen_HK
dc.subject.meshProspective Studiesen_HK
dc.subject.meshReference Valuesen_HK
dc.subject.meshSex Characteristicsen_HK
dc.titleExhaled nitric oxide: The effects of age, gender and body sizeen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0341-2040&volume=179&spage=83&epage=91&date=2001&atitle=Exhaled+nitric+oxide:+The+effects+of+age,+gender+and+body+sizeen_HK
dc.identifier.emailTipoe, GL:tgeorge@hkucc.hku.hken_HK
dc.identifier.emailIp, MS:msmip@hku.hken_HK
dc.identifier.authorityTipoe, GL=rp00371en_HK
dc.identifier.authorityIp, MS=rp00347en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s004080000050en_HK
dc.identifier.pmid11733851-
dc.identifier.scopuseid_2-s2.0-0034748521en_HK
dc.identifier.hkuros74725en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034748521&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume179en_HK
dc.identifier.issue2en_HK
dc.identifier.spage83en_HK
dc.identifier.epage91en_HK
dc.identifier.isiWOS:000172007700002-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTsang, KW=7201555024en_HK
dc.identifier.scopusauthoridIp, SK=7006626424en_HK
dc.identifier.scopusauthoridLeung, R=7101876102en_HK
dc.identifier.scopusauthoridTipoe, GL=7003550610en_HK
dc.identifier.scopusauthoridChan, SL=14055434000en_HK
dc.identifier.scopusauthoridShum, IH=6602960338en_HK
dc.identifier.scopusauthoridIp, MS=7102423259en_HK
dc.identifier.scopusauthoridYan, C=35106566600en_HK
dc.identifier.scopusauthoridFung, PC=7101613315en_HK
dc.identifier.scopusauthoridChanYeung, M=54790582200en_HK
dc.identifier.scopusauthoridLam, W=7203021937en_HK

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