Links for fulltext
     (May Require Subscription)

Article: Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract

TitleTropism of avian influenza A (H5N1) in the upper and lower respiratory tract
Authors
Issue Date2007
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/nm
Citation
Nature Medicine, 2007, v. 13 n. 2, p. 147-149 How to Cite?
AbstractPoor human-to-human transmission of influenza A H5N1 virus has been attributed to the paucity of putative sialic acid α2-3 virus receptors in the epithelium of the human upper respiratory tract, and thus to the presumed inability of the virus to replicate efficiently at this site. We now demonstrate that ex vivo cultures of human nasopharyngeal, adenoid and tonsillar tissues can be infected with H5N1 viruses in spite of an apparent lack of these receptors. © 2007 Nature Publishing Group.
Persistent Identifierhttp://hdl.handle.net/10722/67689
ISSN
2014 Impact Factor: 27.363
2013 SCImago Journal Rankings: 10.988
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNicholls, JMen_HK
dc.contributor.authorChan, MCWen_HK
dc.contributor.authorChan, WYen_HK
dc.contributor.authorWong, HKen_HK
dc.contributor.authorCheung, CYen_HK
dc.contributor.authorKwong, DLWen_HK
dc.contributor.authorWong, MPen_HK
dc.contributor.authorChui, WHen_HK
dc.contributor.authorPoon, LLMen_HK
dc.contributor.authorTsao, SWen_HK
dc.contributor.authorGuan, Yen_HK
dc.contributor.authorPeiris, JSMen_HK
dc.date.accessioned2010-09-06T05:57:22Z-
dc.date.available2010-09-06T05:57:22Z-
dc.date.issued2007en_HK
dc.identifier.citationNature Medicine, 2007, v. 13 n. 2, p. 147-149en_HK
dc.identifier.issn1078-8956en_HK
dc.identifier.urihttp://hdl.handle.net/10722/67689-
dc.description.abstractPoor human-to-human transmission of influenza A H5N1 virus has been attributed to the paucity of putative sialic acid α2-3 virus receptors in the epithelium of the human upper respiratory tract, and thus to the presumed inability of the virus to replicate efficiently at this site. We now demonstrate that ex vivo cultures of human nasopharyngeal, adenoid and tonsillar tissues can be infected with H5N1 viruses in spite of an apparent lack of these receptors. © 2007 Nature Publishing Group.en_HK
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/nmen_HK
dc.relation.ispartofNature Medicineen_HK
dc.subject.meshInfluenza A Virus, H5N1 Subtype - metabolism-
dc.subject.meshInfluenza, Human - metabolism - transmission-
dc.subject.meshReceptors, Cell Surface - metabolism-
dc.subject.meshRespiratory System - virology-
dc.subject.meshVirus Attachment-
dc.titleTropism of avian influenza A (H5N1) in the upper and lower respiratory tracten_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1078-8956&volume=13&issue=2&spage=147&epage=149&date=2007&atitle=Tropism+of+avian+influenza+A+(H5N1)+in+the+upper+and+lower+respiratory+tracten_HK
dc.identifier.emailNicholls, JM: jmnichol@hkucc.hku.hken_HK
dc.identifier.emailChan, MCW: mchan@hku.hken_HK
dc.identifier.emailChan, WY: reneewy@hku.hken_HK
dc.identifier.emailCheung, CY: chungey@hkucc.hku.hken_HK
dc.identifier.emailKwong, DLW: dlwkwong@hku.hken_HK
dc.identifier.emailWong, MP: mwpik@hkucc.hku.hken_HK
dc.identifier.emailPoon, LLM: llmpoon@hkucc.hku.hken_HK
dc.identifier.emailTsao, SW: gswtsao@hku.hken_HK
dc.identifier.emailGuan, Y: yguan@hkucc.hku.hken_HK
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hken_HK
dc.identifier.authorityNicholls, JM=rp00364en_HK
dc.identifier.authorityChan, MCW=rp00420en_HK
dc.identifier.authorityChan, WY=rp01596en_HK
dc.identifier.authorityCheung, CY=rp00404en_HK
dc.identifier.authorityKwong, DLW=rp00414en_HK
dc.identifier.authorityWong, MP=rp00348en_HK
dc.identifier.authorityPoon, LLM=rp00484en_HK
dc.identifier.authorityTsao, SW=rp00399en_HK
dc.identifier.authorityGuan, Y=rp00397en_HK
dc.identifier.authorityPeiris, JSM=rp00410en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/nm1529en_HK
dc.identifier.pmid17206149-
dc.identifier.scopuseid_2-s2.0-33846995616en_HK
dc.identifier.hkuros151573-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33846995616&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume13en_HK
dc.identifier.issue2en_HK
dc.identifier.spage147en_HK
dc.identifier.epage149en_HK
dc.identifier.eissn1546-170X-
dc.identifier.isiWOS:000244031700022-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridNicholls, JM=7201463077en_HK
dc.identifier.scopusauthoridChan, MCW=26654715500en_HK
dc.identifier.scopusauthoridChan, WY=26661379100en_HK
dc.identifier.scopusauthoridWong, HK=12761383400en_HK
dc.identifier.scopusauthoridCheung, CY=7202061836en_HK
dc.identifier.scopusauthoridKwong, DLW=15744231600en_HK
dc.identifier.scopusauthoridWong, MP=7403907887en_HK
dc.identifier.scopusauthoridChui, WH=7003524497en_HK
dc.identifier.scopusauthoridPoon, LLM=7005441747en_HK
dc.identifier.scopusauthoridTsao, SW=7102813116en_HK
dc.identifier.scopusauthoridGuan, Y=7202924055en_HK
dc.identifier.scopusauthoridPeiris, JSM=7005486823en_HK
dc.identifier.citeulike1091781-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats