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Article: Retinal nerve fiber loss in high- and normal-tension glaucoma by optical coherence tomography

TitleRetinal nerve fiber loss in high- and normal-tension glaucoma by optical coherence tomography
Authors
Issue Date2004
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.optvissci.com
Citation
Optometry And Vision Science, 2004, v. 81 n. 5, p. 369-372 How to Cite?
AbstractPurpose. To compare the pattern of retinal nerve fiber layer (RNFL) damages in high-tension and normal-tension primary chronic open-angle glaucoma using optical coherence tomography (OCT). Methods. Age- and refractive error-matched patients with normal-tension glaucoma (NTG) (n = 38) and high-tension glaucoma (HTG) (n = 48) and normal subjects (n = 48) were recruited. All subjects underwent complete eye examinations and OCT RNFL assessments. Results. No statistically significant difference was found between eyes with HTG and NTG for any OCT RNFL thickness parameters (p < 0.05). Inferotemporal thickness values were significantly lower than the superotemporal thickness values in both glaucoma groups (p < 0.001), but no difference was observed in the normal group. Compared with the results from normal subjects, several OCT parameters, including average, superior, inferior, inferotemporal, and superotemporal values, were significantly lower in patients with HTG and NTG (p < 0.01). Conclusions. A mixture of diffuse RNFL damage (superotemporal and inferotemporal regions) and local damage in inferotemporal region was observed in patients with HTG and NTG, suggesting that HTG and NTG may undergo same pathological process.
Persistent Identifierhttp://hdl.handle.net/10722/67618
ISSN
2015 Impact Factor: 1.442
2015 SCImago Journal Rankings: 0.857
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMok, KHen_HK
dc.contributor.authorLee, VWHen_HK
dc.contributor.authorSo, KFen_HK
dc.date.accessioned2010-09-06T05:56:44Z-
dc.date.available2010-09-06T05:56:44Z-
dc.date.issued2004en_HK
dc.identifier.citationOptometry And Vision Science, 2004, v. 81 n. 5, p. 369-372en_HK
dc.identifier.issn1040-5488en_HK
dc.identifier.urihttp://hdl.handle.net/10722/67618-
dc.description.abstractPurpose. To compare the pattern of retinal nerve fiber layer (RNFL) damages in high-tension and normal-tension primary chronic open-angle glaucoma using optical coherence tomography (OCT). Methods. Age- and refractive error-matched patients with normal-tension glaucoma (NTG) (n = 38) and high-tension glaucoma (HTG) (n = 48) and normal subjects (n = 48) were recruited. All subjects underwent complete eye examinations and OCT RNFL assessments. Results. No statistically significant difference was found between eyes with HTG and NTG for any OCT RNFL thickness parameters (p < 0.05). Inferotemporal thickness values were significantly lower than the superotemporal thickness values in both glaucoma groups (p < 0.001), but no difference was observed in the normal group. Compared with the results from normal subjects, several OCT parameters, including average, superior, inferior, inferotemporal, and superotemporal values, were significantly lower in patients with HTG and NTG (p < 0.01). Conclusions. A mixture of diffuse RNFL damage (superotemporal and inferotemporal regions) and local damage in inferotemporal region was observed in patients with HTG and NTG, suggesting that HTG and NTG may undergo same pathological process.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.optvissci.comen_HK
dc.relation.ispartofOptometry and Vision Scienceen_HK
dc.rightsOptometry and Vision Science. Copyright © Lippincott Williams & Wilkins.en_HK
dc.subject.meshChronic Diseaseen_HK
dc.subject.meshCross-Sectional Studiesen_HK
dc.subject.meshDiagnostic Techniques, Ophthalmologicalen_HK
dc.subject.meshGlaucoma, Open-Angle - diagnosisen_HK
dc.subject.meshHumansen_HK
dc.subject.meshIntraocular Pressureen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNerve Fibers - pathologyen_HK
dc.subject.meshOptic Nerve Diseases - diagnosisen_HK
dc.subject.meshRetinal Ganglion Cells - pathologyen_HK
dc.subject.meshTomography, Optical Coherenceen_HK
dc.subject.meshTonometry, Ocularen_HK
dc.titleRetinal nerve fiber loss in high- and normal-tension glaucoma by optical coherence tomographyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1040-5488&volume=81 no 5&spage=369&epage=372&date=2004&atitle=Retinal+nerve+fiber+loss+in+high-+and+normal-tension+glaucoma+by+optical+coherence+tomographyen_HK
dc.identifier.emailSo, KF:hrmaskf@hkucc.hku.hken_HK
dc.identifier.authoritySo, KF=rp00329en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/01.opx.0000134911.36521.b4en_HK
dc.identifier.pmid15181362-
dc.identifier.scopuseid_2-s2.0-2542590199en_HK
dc.identifier.hkuros95517en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-2542590199&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume81en_HK
dc.identifier.issue5en_HK
dc.identifier.spage369en_HK
dc.identifier.epage372en_HK
dc.identifier.isiWOS:000221566900010-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridMok, KH=7103141187en_HK
dc.identifier.scopusauthoridLee, VWH=7402507569en_HK
dc.identifier.scopusauthoridSo, KF=34668391300en_HK

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