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Article: Peptidergic innervation of the human clitoris

TitlePeptidergic innervation of the human clitoris
Authors
Issue Date1999
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/peptides
Citation
Peptides, 1999, v. 20 n. 5, p. 539-543 How to Cite?
AbstractIn the present study, the distributions of neuropeptides in the normal human clitoris and in a clitoris from an adrenogenital syndrome (AGS) was demonstrated by immunohistochemistry (IHC). Immunohistochemical screening detected a complex network of nerve fibers containing vasoactive intestinal polypeptide (VIP), peptide histidine methionine (PHM), neuropeptide tyrosine (neuropeptide Y), C-flanking peptide of neuropeptide Y (CPON), calcitonin gene-related peptide (CGRP) and substance P immunoreactivities. Special attention was given to the VIP-related peptide helospectin, that has been detected in neuronal elements in the clitoris. No visible differences between the localization and distribution of peptidergic nerve fibers of normal and hypertrophic clitoris from AGS have been observed. Co-localization studies showed the co-existence of VIP, PHM and partly helospectin and neuropeptide Y with CPON within nerve fibers in the cavernous tissue and substance P and CGRP co-expression in nerve fibers especially underneath and within the glans clitoris. Copyright (C) 1999 Elsevier Science Inc.
Persistent Identifierhttp://hdl.handle.net/10722/67560
ISSN
2015 Impact Factor: 2.535
2015 SCImago Journal Rankings: 1.128
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHauserKronberger, Cen_HK
dc.contributor.authorCheung, Aen_HK
dc.contributor.authorHacker, GWen_HK
dc.contributor.authorGraf, AHen_HK
dc.contributor.authorDietze, Oen_HK
dc.contributor.authorFrick, Jen_HK
dc.date.accessioned2010-09-06T05:56:13Z-
dc.date.available2010-09-06T05:56:13Z-
dc.date.issued1999en_HK
dc.identifier.citationPeptides, 1999, v. 20 n. 5, p. 539-543en_HK
dc.identifier.issn0196-9781en_HK
dc.identifier.urihttp://hdl.handle.net/10722/67560-
dc.description.abstractIn the present study, the distributions of neuropeptides in the normal human clitoris and in a clitoris from an adrenogenital syndrome (AGS) was demonstrated by immunohistochemistry (IHC). Immunohistochemical screening detected a complex network of nerve fibers containing vasoactive intestinal polypeptide (VIP), peptide histidine methionine (PHM), neuropeptide tyrosine (neuropeptide Y), C-flanking peptide of neuropeptide Y (CPON), calcitonin gene-related peptide (CGRP) and substance P immunoreactivities. Special attention was given to the VIP-related peptide helospectin, that has been detected in neuronal elements in the clitoris. No visible differences between the localization and distribution of peptidergic nerve fibers of normal and hypertrophic clitoris from AGS have been observed. Co-localization studies showed the co-existence of VIP, PHM and partly helospectin and neuropeptide Y with CPON within nerve fibers in the cavernous tissue and substance P and CGRP co-expression in nerve fibers especially underneath and within the glans clitoris. Copyright (C) 1999 Elsevier Science Inc.en_HK
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/peptidesen_HK
dc.relation.ispartofPeptidesen_HK
dc.rightsPeptides. Copyright © Elsevier BV.en_HK
dc.subject.meshAdrenal Hyperplasia, Congenital - pathologyen_HK
dc.subject.meshBlood Vessels - innervationen_HK
dc.subject.meshClitoris - innervationen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshNerve Neten_HK
dc.subject.meshNeuropeptides - isolation & purificationen_HK
dc.subject.meshVasoconstrictor Agents - isolation & purificationen_HK
dc.subject.meshVasodilator Agents - isolation & purificationen_HK
dc.titlePeptidergic innervation of the human clitorisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0079-0753&volume=20&spage=539&epage=543&date=1999&atitle=Peptidergic+innervation+of+the+human+clitorisen_HK
dc.identifier.emailCheung, A:lmcheung@hkucc.hku.hken_HK
dc.identifier.authorityCheung, A=rp00332en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0196-9781(99)00005-4en_HK
dc.identifier.pmid10465504-
dc.identifier.scopuseid_2-s2.0-0032852849en_HK
dc.identifier.hkuros46872en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032852849&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume20en_HK
dc.identifier.issue5en_HK
dc.identifier.spage539en_HK
dc.identifier.epage543en_HK
dc.identifier.isiWOS:000082077600001-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHauserKronberger, C=7003360268en_HK
dc.identifier.scopusauthoridCheung, A=7401806497en_HK
dc.identifier.scopusauthoridHacker, GW=7006705677en_HK
dc.identifier.scopusauthoridGraf, AH=7006625267en_HK
dc.identifier.scopusauthoridDietze, O=24798646300en_HK
dc.identifier.scopusauthoridFrick, J=7102505326en_HK

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