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Article: Ciliary assessment in bronchiectasis

TitleCiliary assessment in bronchiectasis
Authors
Issue Date2000
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/RES
Citation
Respirology, 2000, v. 5 n. 2, p. 91-98 How to Cite?
AbstractBronchiectasis is a common condition among the Oriental population and affected patients suffer from chronic sputum production punctuated by recurrent infective exacerbations. Cilia are minute structures present on the surface of respiratory and other epithelial cells that beat continuously to maintain a sterile mucosal surface in the respiratory tract. Patients with primary ciliary dyskinesia could potentially develop recurrent sinotrachrobronchitis, bronchiectasis, serous otitis media, hydrocephalus, and male infertility. The assessment of cilia has, however, received little attention until recently and generally involves elaborate methods that require complex and expensive technology. This brief article discusses application of the saccharine test, light microscopy assessment of ciliary beat, and transmission electron microscopy assessment of the ultrastructure of cilia. The rationale and indications for ciliary assessment are also listed along with illustrations showing ciliary structure, equipment required for sampling and assessment of cilia, and transmission electron micrographs of ciliary ultrastructural abnormalities.
Persistent Identifierhttp://hdl.handle.net/10722/67460
ISSN
2015 Impact Factor: 3.078
2015 SCImago Journal Rankings: 1.157
References

 

DC FieldValueLanguage
dc.contributor.authorTsang, KWTen_HK
dc.contributor.authorZheng, Len_HK
dc.contributor.authorTipoe, Gen_HK
dc.date.accessioned2010-09-06T05:55:20Z-
dc.date.available2010-09-06T05:55:20Z-
dc.date.issued2000en_HK
dc.identifier.citationRespirology, 2000, v. 5 n. 2, p. 91-98en_HK
dc.identifier.issn1323-7799en_HK
dc.identifier.urihttp://hdl.handle.net/10722/67460-
dc.description.abstractBronchiectasis is a common condition among the Oriental population and affected patients suffer from chronic sputum production punctuated by recurrent infective exacerbations. Cilia are minute structures present on the surface of respiratory and other epithelial cells that beat continuously to maintain a sterile mucosal surface in the respiratory tract. Patients with primary ciliary dyskinesia could potentially develop recurrent sinotrachrobronchitis, bronchiectasis, serous otitis media, hydrocephalus, and male infertility. The assessment of cilia has, however, received little attention until recently and generally involves elaborate methods that require complex and expensive technology. This brief article discusses application of the saccharine test, light microscopy assessment of ciliary beat, and transmission electron microscopy assessment of the ultrastructure of cilia. The rationale and indications for ciliary assessment are also listed along with illustrations showing ciliary structure, equipment required for sampling and assessment of cilia, and transmission electron micrographs of ciliary ultrastructural abnormalities.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/RESen_HK
dc.relation.ispartofRespirologyen_HK
dc.subject.meshBronchiectasis - pathologyen_HK
dc.subject.meshCilia - ultrastructureen_HK
dc.subject.meshCiliary Motility Disorders - diagnosis - pathologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMicroscopyen_HK
dc.subject.meshMicroscopy, Electronen_HK
dc.subject.meshMovementen_HK
dc.subject.meshRespiratory System - pathologyen_HK
dc.subject.meshSaccharin - diagnostic useen_HK
dc.titleCiliary assessment in bronchiectasisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1323-7799&volume=5&spage=91&epage=98&date=2000&atitle=Ciliary+assessment+in+bronchiectasisen_HK
dc.identifier.emailTipoe, G:tgeorge@hkucc.hku.hken_HK
dc.identifier.authorityTipoe, G=rp00371en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1046/j.1440-1843.2000.00233.xen_HK
dc.identifier.pmid10894096-
dc.identifier.scopuseid_2-s2.0-0033935870en_HK
dc.identifier.hkuros49605en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033935870&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume5en_HK
dc.identifier.issue2en_HK
dc.identifier.spage91en_HK
dc.identifier.epage98en_HK
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridTsang, KWT=7201555024en_HK
dc.identifier.scopusauthoridZheng, L=7403404086en_HK
dc.identifier.scopusauthoridTipoe, G=7003550610en_HK

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