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Article: Retinal nerve fiber loss pattern in high-tension glaucoma by optical coherence tomography

TitleRetinal nerve fiber loss pattern in high-tension glaucoma by optical coherence tomography
Authors
Issue Date2003
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.glaucomajournal.com
Citation
Journal Of Glaucoma, 2003, v. 12 n. 3, p. 255-259 How to Cite?
AbstractPurpose: To identify the pattern of retinal nerve fiber layer thinning in high-tension primary chronic open-angle glaucoma (HT-PCOAG) using optical coherence tomography. Methods: Retinal nerve fiber layer thickness was assessed with optical coherence tomography in 68 healthy controls and 68 age- and refractive error-matched patients with HT-PCOAG were recruited. Patients were divided into 3 subgroups according to their visual field mean deviation: early (> -3 dB), moderate (-3 to -7 dB), and moderately advanced (-7 to -15 dB). Results: Retinal nerve fiber layer thickness values in inferotemporal and superotemporal regions were significantly lower in all groups of glaucomatous eyes than in healthy eyes (P<0.001). Inferotemporal thickness values were significantly lower than the superotemporal thickness values (P<0.001) in the early glaucomatous stage, but not significantly so in moderate and moderately advanced stages. Conclusions: Besides a diffuse retinal nerve fiber layer defect, a localized defect may present in the inferotemporal region in early-stage HT-PCOAG. These results also suggest that optical coherence tomography shows promise in providing quantitative data about the location and extent of retinal nerve fiber layer injury in glaucoma, and the findings are consistent with previous knowledge.
Persistent Identifierhttp://hdl.handle.net/10722/67446
ISSN
2015 Impact Factor: 2.102
2015 SCImago Journal Rankings: 1.477
References

 

DC FieldValueLanguage
dc.contributor.authorMok, KHen_HK
dc.contributor.authorLee, VWHen_HK
dc.contributor.authorSo, KFen_HK
dc.date.accessioned2010-09-06T05:55:12Z-
dc.date.available2010-09-06T05:55:12Z-
dc.date.issued2003en_HK
dc.identifier.citationJournal Of Glaucoma, 2003, v. 12 n. 3, p. 255-259en_HK
dc.identifier.issn1057-0829en_HK
dc.identifier.urihttp://hdl.handle.net/10722/67446-
dc.description.abstractPurpose: To identify the pattern of retinal nerve fiber layer thinning in high-tension primary chronic open-angle glaucoma (HT-PCOAG) using optical coherence tomography. Methods: Retinal nerve fiber layer thickness was assessed with optical coherence tomography in 68 healthy controls and 68 age- and refractive error-matched patients with HT-PCOAG were recruited. Patients were divided into 3 subgroups according to their visual field mean deviation: early (> -3 dB), moderate (-3 to -7 dB), and moderately advanced (-7 to -15 dB). Results: Retinal nerve fiber layer thickness values in inferotemporal and superotemporal regions were significantly lower in all groups of glaucomatous eyes than in healthy eyes (P<0.001). Inferotemporal thickness values were significantly lower than the superotemporal thickness values (P<0.001) in the early glaucomatous stage, but not significantly so in moderate and moderately advanced stages. Conclusions: Besides a diffuse retinal nerve fiber layer defect, a localized defect may present in the inferotemporal region in early-stage HT-PCOAG. These results also suggest that optical coherence tomography shows promise in providing quantitative data about the location and extent of retinal nerve fiber layer injury in glaucoma, and the findings are consistent with previous knowledge.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.glaucomajournal.comen_HK
dc.relation.ispartofJournal of Glaucomaen_HK
dc.rightsJournal of Glaucoma. Copyright © Lippincott Williams & Wilkins.en_HK
dc.subject.meshAdulten_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGlaucoma - pathology - physiopathologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshIntraocular Pressureen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNerve Fibers - pathologyen_HK
dc.subject.meshRetina - pathologyen_HK
dc.subject.meshTomographyen_HK
dc.titleRetinal nerve fiber loss pattern in high-tension glaucoma by optical coherence tomographyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1057-0829&volume=12&spage=255&epage=259&date=2003&atitle=Retinal+nerve+fiber+loss+pattern+in+high-tension+glaucoma+by+optical+coherence+tomographyen_HK
dc.identifier.emailSo, KF:hrmaskf@hkucc.hku.hken_HK
dc.identifier.authoritySo, KF=rp00329en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/00061198-200306000-00013en_HK
dc.identifier.pmid12782845-
dc.identifier.scopuseid_2-s2.0-0037973245en_HK
dc.identifier.hkuros78453en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0037973245&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume12en_HK
dc.identifier.issue3en_HK
dc.identifier.spage255en_HK
dc.identifier.epage259en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridMok, KH=7103141187en_HK
dc.identifier.scopusauthoridLee, VWH=7402507569en_HK
dc.identifier.scopusauthoridSo, KF=34668391300en_HK

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