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Article: Severe bronchiectasis in patients with 'cystlike' structures within the ciliary shafts

TitleSevere bronchiectasis in patients with 'cystlike' structures within the ciliary shafts
Authors
Issue Date2000
PublisherAmerican Thoracic Society. The Journal's web site is located at http://ajrccm.atsjournals.org
Citation
American Journal Of Respiratory And Critical Care Medicine, 2000, v. 161 n. 4 I, p. 1300-1305 How to Cite?
AbstractCilia are minute hairlike structures which sweep the respiratory tract clean by continuous beating. Ciliary dysfunction can occur which leads to development of bronchiectasis. We describe the clinical and investigation profiles of four patients who had early-onset severe and otherwise idiopathic bronchiectasis associated with a previously undescribed ciliary defect in which numerous cystlike structures are present within the ciliary shafts. The patients had otherwise normal ciliary microtubular ultrastructure and central microtubular orientation. Our newly described ciliary abnormality appears to be a primary defect and more systematic studies should be performed to evaluate this further.
Persistent Identifierhttp://hdl.handle.net/10722/67412
ISSN
2015 Impact Factor: 13.118
2015 SCImago Journal Rankings: 5.832
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTsang, KWTen_HK
dc.contributor.authorTipoe, Gen_HK
dc.contributor.authorSun, Jen_HK
dc.contributor.authorHo, JCMen_HK
dc.contributor.authorLam, Ben_HK
dc.contributor.authorZheng, Len_HK
dc.contributor.authorOoi, GCen_HK
dc.contributor.authorIp, Men_HK
dc.contributor.authorLam, WKen_HK
dc.date.accessioned2010-09-06T05:54:55Z-
dc.date.available2010-09-06T05:54:55Z-
dc.date.issued2000en_HK
dc.identifier.citationAmerican Journal Of Respiratory And Critical Care Medicine, 2000, v. 161 n. 4 I, p. 1300-1305en_HK
dc.identifier.issn1073-449Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/67412-
dc.description.abstractCilia are minute hairlike structures which sweep the respiratory tract clean by continuous beating. Ciliary dysfunction can occur which leads to development of bronchiectasis. We describe the clinical and investigation profiles of four patients who had early-onset severe and otherwise idiopathic bronchiectasis associated with a previously undescribed ciliary defect in which numerous cystlike structures are present within the ciliary shafts. The patients had otherwise normal ciliary microtubular ultrastructure and central microtubular orientation. Our newly described ciliary abnormality appears to be a primary defect and more systematic studies should be performed to evaluate this further.en_HK
dc.languageengen_HK
dc.publisherAmerican Thoracic Society. The Journal's web site is located at http://ajrccm.atsjournals.orgen_HK
dc.relation.ispartofAmerican Journal of Respiratory and Critical Care Medicineen_HK
dc.subject.meshAdulten_HK
dc.subject.meshBronchiectasis - pathology - radiographyen_HK
dc.subject.meshCilia - ultrastructureen_HK
dc.subject.meshCystsen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMicroscopy, Electronen_HK
dc.subject.meshMicrotubules - ultrastructureen_HK
dc.subject.meshTomography, X-Ray Computeden_HK
dc.titleSevere bronchiectasis in patients with 'cystlike' structures within the ciliary shaftsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1073-449X&volume=161&spage=1300&epage=1305&date=2000&atitle=Severe+bronchiectasis+in+patients+with+%27cystlike%27+structures+within+the+ciliary+shaftsen_HK
dc.identifier.emailTipoe, G:tgeorge@hkucc.hku.hken_HK
dc.identifier.emailHo, JCM:jhocm@hku.hken_HK
dc.identifier.emailIp, M:msmip@hku.hken_HK
dc.identifier.authorityTipoe, G=rp00371en_HK
dc.identifier.authorityHo, JCM=rp00258en_HK
dc.identifier.authorityIp, M=rp00347en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid10764327-
dc.identifier.scopuseid_2-s2.0-0034014303en_HK
dc.identifier.hkuros49618en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034014303&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume161en_HK
dc.identifier.issue4 Ien_HK
dc.identifier.spage1300en_HK
dc.identifier.epage1305en_HK
dc.identifier.isiWOS:000086573400038-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTsang, KWT=7201555024en_HK
dc.identifier.scopusauthoridTipoe, G=7003550610en_HK
dc.identifier.scopusauthoridSun, J=7410371598en_HK
dc.identifier.scopusauthoridHo, JCM=7402649981en_HK
dc.identifier.scopusauthoridLam, B=9246012800en_HK
dc.identifier.scopusauthoridZheng, L=7403404086en_HK
dc.identifier.scopusauthoridOoi, GC=7006176119en_HK
dc.identifier.scopusauthoridIp, M=7102423259en_HK
dc.identifier.scopusauthoridLam, WK=7203021937en_HK

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