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Article: The development of hypercoagulability state, as measured by thrombelastography, associated with intraoperative surgical blood loss

TitleThe development of hypercoagulability state, as measured by thrombelastography, associated with intraoperative surgical blood loss
Authors
Issue Date1996
PublisherAustralian Society of Anaesthetists. The Journal's web site is located at http://www.aaic.net.au
Citation
Anaesthesia And Intensive Care, 1996, v. 24 n. 1, p. 20-25 How to Cite?
AbstractThrombelastographic evidence of hypercoagulability, including shortening of r-time (P<0.01); shortening of k-time (P<0.01); and widening of trace angle (P<0.01) were observed in a group of 21 Chinese surgical patients when (a) the amount of blood loss was at an estimated 10% of total blood volume and (b) the amount of blood loss was at an estimated 15% of blood volume. The amount of blood loss was documented by haemoglobin measurements. No evidence of hypercoagulability,vas observed at around one hour into the operation in the absence of bleeding. We conclude that a mild to moderate degree of surgical blood loss with haemodilution is associated with the development of hypercoagulability as measured by thrombelastography. Further studies looking at the thrombebolic outcome in such groups of patients is warranted. It is also suggested that caution should be exercised in the use of intraoperative isovolaemic haemoldilution until the phenomenon is further investigated.
Persistent Identifierhttp://hdl.handle.net/10722/67305
ISSN
2015 Impact Factor: 1.283
2015 SCImago Journal Rankings: 0.488
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, KFJen_HK
dc.contributor.authorLo, JWRen_HK
dc.date.accessioned2010-09-06T05:53:48Z-
dc.date.available2010-09-06T05:53:48Z-
dc.date.issued1996en_HK
dc.identifier.citationAnaesthesia And Intensive Care, 1996, v. 24 n. 1, p. 20-25en_HK
dc.identifier.issn0310-057Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/67305-
dc.description.abstractThrombelastographic evidence of hypercoagulability, including shortening of r-time (P<0.01); shortening of k-time (P<0.01); and widening of trace angle (P<0.01) were observed in a group of 21 Chinese surgical patients when (a) the amount of blood loss was at an estimated 10% of total blood volume and (b) the amount of blood loss was at an estimated 15% of blood volume. The amount of blood loss was documented by haemoglobin measurements. No evidence of hypercoagulability,vas observed at around one hour into the operation in the absence of bleeding. We conclude that a mild to moderate degree of surgical blood loss with haemodilution is associated with the development of hypercoagulability as measured by thrombelastography. Further studies looking at the thrombebolic outcome in such groups of patients is warranted. It is also suggested that caution should be exercised in the use of intraoperative isovolaemic haemoldilution until the phenomenon is further investigated.en_HK
dc.languageengen_HK
dc.publisherAustralian Society of Anaesthetists. The Journal's web site is located at http://www.aaic.net.auen_HK
dc.relation.ispartofAnaesthesia and Intensive Careen_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshBlood Coagulation Disorders - diagnosis - etiologyen_HK
dc.subject.meshBlood Loss, Surgicalen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHemodilution - adverse effectsen_HK
dc.subject.meshHumansen_HK
dc.subject.meshIntraoperative Perioden_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshThrombelastography - methodsen_HK
dc.titleThe development of hypercoagulability state, as measured by thrombelastography, associated with intraoperative surgical blood lossen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0310-057X&volume=24&spage=20&epage=25&date=1996&atitle=The+development+of+hypercoagulability+state,+as+measured+by+thrombelastography,+associated+with+intraoperative+surgical+blood+lossen_HK
dc.identifier.emailNg, KFJ:jkfng@hkucc.hku.hken_HK
dc.identifier.authorityNg, KFJ=rp00544en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid8669648-
dc.identifier.scopuseid_2-s2.0-0030057644en_HK
dc.identifier.hkuros15301en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030057644&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume24en_HK
dc.identifier.issue1en_HK
dc.identifier.spage20en_HK
dc.identifier.epage25en_HK
dc.identifier.isiWOS:A1996TW75000004-
dc.publisher.placeAustraliaen_HK

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