File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Prevention of postoperative nausea and vomiting in gynaecological laparotomies: A comparison of tropisetron and ondansetron

TitlePrevention of postoperative nausea and vomiting in gynaecological laparotomies: A comparison of tropisetron and ondansetron
Authors
KeywordsAnalgesia: patient-controlled, morphine
Antiemetic: tropisetron, ondansetron
Surgery: gynaecological, laparotomy
Issue Date1999
PublisherAustralian Society of Anaesthetists. The Journal's web site is located at http://www.aaic.net.au
Citation
Anaesthesia And Intensive Care, 1999, v. 27 n. 5, p. 471-476 How to Cite?
AbstractIn a randomized, double-blind study, the antiemetic efficacy of a single bolus of tropisetron 5 mg (group T, 37 patients), ondansetron 4 mg (group O, 39 patients) or saline (group C, 45 patients) given at induction was compared in a homogeneous group of 121 patients undergoing gynaecological laparotomy and receiving postoperative patient- controlled intravenous morphine for 24 to 48 hours. Fewer group T and group O patients developed severe nausea compared to group C (P < 0.01, log rank test in Kaplan-Meier analysis). Group T patients also had lower nausea scores than group O at 8 to 16 h (P < 0.05). The overall incidences of severe nausea in groups T, O, and C were 5.4%, 17.9%, and 44.4% respectively (P < 0.001, group T vs group C; P < 0.05 group O vs group C). In conclusion, the 5-hydroxytryptamine 3 receptor antagonists tropisetron and ondansetron were superior to placebo in preventing PONV.
Persistent Identifierhttp://hdl.handle.net/10722/67304
ISSN
2015 Impact Factor: 1.283
2015 SCImago Journal Rankings: 0.488
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTsui, SLen_HK
dc.contributor.authorNg, KFJen_HK
dc.contributor.authorWong, LCen_HK
dc.contributor.authorTang, GWKen_HK
dc.contributor.authorPun, TCen_HK
dc.contributor.authorYang, JCSen_HK
dc.date.accessioned2010-09-06T05:53:48Z-
dc.date.available2010-09-06T05:53:48Z-
dc.date.issued1999en_HK
dc.identifier.citationAnaesthesia And Intensive Care, 1999, v. 27 n. 5, p. 471-476en_HK
dc.identifier.issn0310-057Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/67304-
dc.description.abstractIn a randomized, double-blind study, the antiemetic efficacy of a single bolus of tropisetron 5 mg (group T, 37 patients), ondansetron 4 mg (group O, 39 patients) or saline (group C, 45 patients) given at induction was compared in a homogeneous group of 121 patients undergoing gynaecological laparotomy and receiving postoperative patient- controlled intravenous morphine for 24 to 48 hours. Fewer group T and group O patients developed severe nausea compared to group C (P < 0.01, log rank test in Kaplan-Meier analysis). Group T patients also had lower nausea scores than group O at 8 to 16 h (P < 0.05). The overall incidences of severe nausea in groups T, O, and C were 5.4%, 17.9%, and 44.4% respectively (P < 0.001, group T vs group C; P < 0.05 group O vs group C). In conclusion, the 5-hydroxytryptamine 3 receptor antagonists tropisetron and ondansetron were superior to placebo in preventing PONV.en_HK
dc.languageengen_HK
dc.publisherAustralian Society of Anaesthetists. The Journal's web site is located at http://www.aaic.net.auen_HK
dc.relation.ispartofAnaesthesia and Intensive Careen_HK
dc.subjectAnalgesia: patient-controlled, morphineen_HK
dc.subjectAntiemetic: tropisetron, ondansetronen_HK
dc.subjectSurgery: gynaecological, laparotomyen_HK
dc.subject.meshAntiemetics - therapeutic useen_HK
dc.subject.meshGynecologic Surgical Proceduresen_HK
dc.subject.meshIndoles - therapeutic useen_HK
dc.subject.meshLaparotomyen_HK
dc.subject.meshOndansetron - therapeutic useen_HK
dc.titlePrevention of postoperative nausea and vomiting in gynaecological laparotomies: A comparison of tropisetron and ondansetronen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0310-057X&volume=27&spage=471&epage=476&date=1999&atitle=Prevention+of+postoperative+nausea+and+vomiting+in+gynaecological+laparotomies:+a+comparison+of+tropisetron+and+ondansetronen_HK
dc.identifier.emailNg, KFJ:jkfng@hkucc.hku.hken_HK
dc.identifier.emailTang, GWK:gwktang@hkucc.hku.hken_HK
dc.identifier.authorityNg, KFJ=rp00544en_HK
dc.identifier.authorityTang, GWK=rp00328en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid10520386en_HK
dc.identifier.scopuseid_2-s2.0-0032867958en_HK
dc.identifier.hkuros48977en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032867958&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume27en_HK
dc.identifier.issue5en_HK
dc.identifier.spage471en_HK
dc.identifier.epage476en_HK
dc.identifier.isiWOS:000082910200006-
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridTsui, SL=7004961361en_HK
dc.identifier.scopusauthoridNg, KFJ=13608809400en_HK
dc.identifier.scopusauthoridWong, LC=7402092003en_HK
dc.identifier.scopusauthoridTang, GWK=7401633864en_HK
dc.identifier.scopusauthoridPun, TC=7005509306en_HK
dc.identifier.scopusauthoridYang, JCS=26631359500en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats