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Article: Thrombelastographic patterns during cryotherapy for recurrent hepatocellular carcinoma

TitleThrombelastographic patterns during cryotherapy for recurrent hepatocellular carcinoma
Authors
KeywordsCryotherapy
Fibrinolysis
Mechanism
Plalelet transfusion
Thrombelastography
Thrombocytopenia
Issue Date1999
PublisherHepato-Gastroenterology. The Journal's web site is located at http://www.thieme.de/hepato/index.html
Citation
Hepato-Gastroenterology, 1999, v. 46 n. 25, p. 448-452 How to Cite?
AbstractA cirrhotic patient with recurrent hepatocellular carcinoma and thrombocytopenia undergoing cryotherapy showed: 1) transient hyperfibrinolysis shortly after platelet transfusion, and 2) evidence of activation of coagulation after freezing and thawing of tumor as measured on the thrombelastography. No anti-fibrinolytic treatment was required for the hyperfibrinolysis which subsided spontaneously in this patient. This case report highlights that: 1) in patients with chronic liver disease, platelet transfusion might potentially worsen rather than improve the hemostatic function by activation of fibrinolysis, and 2) activation of coagulation may underlie the perioperative coagulation changes seen in cryotherapy.
Persistent Identifierhttp://hdl.handle.net/10722/67281
ISSN
2015 Impact Factor: 0.792
2015 SCImago Journal Rankings: 0.446
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, KFJen_HK
dc.date.accessioned2010-09-06T05:53:36Z-
dc.date.available2010-09-06T05:53:36Z-
dc.date.issued1999en_HK
dc.identifier.citationHepato-Gastroenterology, 1999, v. 46 n. 25, p. 448-452en_HK
dc.identifier.issn0172-6390en_HK
dc.identifier.urihttp://hdl.handle.net/10722/67281-
dc.description.abstractA cirrhotic patient with recurrent hepatocellular carcinoma and thrombocytopenia undergoing cryotherapy showed: 1) transient hyperfibrinolysis shortly after platelet transfusion, and 2) evidence of activation of coagulation after freezing and thawing of tumor as measured on the thrombelastography. No anti-fibrinolytic treatment was required for the hyperfibrinolysis which subsided spontaneously in this patient. This case report highlights that: 1) in patients with chronic liver disease, platelet transfusion might potentially worsen rather than improve the hemostatic function by activation of fibrinolysis, and 2) activation of coagulation may underlie the perioperative coagulation changes seen in cryotherapy.en_HK
dc.languageengen_HK
dc.publisherHepato-Gastroenterology. The Journal's web site is located at http://www.thieme.de/hepato/index.htmlen_HK
dc.relation.ispartofHepato-Gastroenterologyen_HK
dc.subjectCryotherapyen_HK
dc.subjectFibrinolysisen_HK
dc.subjectMechanismen_HK
dc.subjectPlalelet transfusionen_HK
dc.subjectThrombelastographyen_HK
dc.subjectThrombocytopeniaen_HK
dc.subject.meshCarcinoma, Hepatocellular - physiopathology - therapy-
dc.subject.meshHemostasis-
dc.subject.meshLiver Neoplasms - physiopathology - therapy-
dc.subject.meshNeoplasm Recurrence, Local - therapy-
dc.subject.meshThrombelastography-
dc.titleThrombelastographic patterns during cryotherapy for recurrent hepatocellular carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.emailNg, KFJ:jkfng@hkucc.hku.hken_HK
dc.identifier.authorityNg, KFJ=rp00544en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid10228839-
dc.identifier.scopuseid_2-s2.0-0032997259en_HK
dc.identifier.hkuros44310en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032997259&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume46en_HK
dc.identifier.issue25en_HK
dc.identifier.spage448en_HK
dc.identifier.epage452en_HK
dc.identifier.isiWOS:000079268000084-
dc.publisher.placeGreeceen_HK

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