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Article: Adjunctive use of chlorhexidine in oral candidoses: A review

TitleAdjunctive use of chlorhexidine in oral candidoses: A review
Authors
Issue Date2001
PublisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1
Citation
Oral Diseases, 2001, v. 7 n. 1, p. 11-17 How to Cite?
AbstractOral candidosis is by far the commonest human fungal infection and manifests in a variety of clinical guises. The main reason for its high incidence appears to be the multiplicity of predisposing factors, which facilitate the conversion of oral commensal Candida to a parasitic existence. Despite the availability of a number of effective antimycotics for the treatment of oral candidoses, failure of therapy is not uncommon owing to the unique environment of the oral cavity where the flushing effect of saliva and the cleansing action of the oral musculature tend to reduce the drug concentration to sub-therapeutic levels. For these and other reasons chlorhexidine is widely prescribed in dentistry both as an antiseptic mouthwash and a denture disinfectant in order to supplement other antifungals. Chlorhexidine has a broad spectrum of antimicrobial activity including Candida albicans and other common non-albicans yeast species. In this review we outline the utility of chlorhexidine as an adjunct to conventional antimycotic therapy in the management of oral Candida infections.
Persistent Identifierhttp://hdl.handle.net/10722/67254
ISSN
2015 Impact Factor: 2.0
2015 SCImago Journal Rankings: 0.828
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorEllepola, ANBen_HK
dc.contributor.authorSamaranayake, LPen_HK
dc.date.accessioned2010-09-06T05:53:16Z-
dc.date.available2010-09-06T05:53:16Z-
dc.date.issued2001en_HK
dc.identifier.citationOral Diseases, 2001, v. 7 n. 1, p. 11-17en_HK
dc.identifier.issn1354-523Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/67254-
dc.description.abstractOral candidosis is by far the commonest human fungal infection and manifests in a variety of clinical guises. The main reason for its high incidence appears to be the multiplicity of predisposing factors, which facilitate the conversion of oral commensal Candida to a parasitic existence. Despite the availability of a number of effective antimycotics for the treatment of oral candidoses, failure of therapy is not uncommon owing to the unique environment of the oral cavity where the flushing effect of saliva and the cleansing action of the oral musculature tend to reduce the drug concentration to sub-therapeutic levels. For these and other reasons chlorhexidine is widely prescribed in dentistry both as an antiseptic mouthwash and a denture disinfectant in order to supplement other antifungals. Chlorhexidine has a broad spectrum of antimicrobial activity including Candida albicans and other common non-albicans yeast species. In this review we outline the utility of chlorhexidine as an adjunct to conventional antimycotic therapy in the management of oral Candida infections.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1en_HK
dc.relation.ispartofOral Diseasesen_HK
dc.subject.meshAnti-Infective Agents, Local - adverse effects - pharmacology - therapeutic useen_HK
dc.subject.meshAntifungal Agents - therapeutic useen_HK
dc.subject.meshBacterial Adhesion - drug effectsen_HK
dc.subject.meshCandida - drug effectsen_HK
dc.subject.meshCandidiasis, Oral - drug therapyen_HK
dc.subject.meshChlorhexidine - adverse effects - pharmacology - therapeutic useen_HK
dc.subject.meshDrug Delivery Systemsen_HK
dc.subject.meshDrug Synergismen_HK
dc.subject.meshHumansen_HK
dc.subject.meshTooth Discoloration - etiologyen_HK
dc.titleAdjunctive use of chlorhexidine in oral candidoses: A reviewen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1354-523X&volume=7&spage=11&epage=17&date=2001&atitle=Adjunctive+use+of+chlorhexidine+in+oral+candidoses:+a+reviewen_HK
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_HK
dc.identifier.authoritySamaranayake, LP=rp00023en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1034/j.1601-0825.2001.0070103.xen_HK
dc.identifier.pmid11354914-
dc.identifier.scopuseid_2-s2.0-0035107647en_HK
dc.identifier.hkuros56569en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035107647&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume7en_HK
dc.identifier.issue1en_HK
dc.identifier.spage11en_HK
dc.identifier.epage17en_HK
dc.identifier.isiWOS:000167595100003-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridEllepola, ANB=6604060863en_HK
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_HK

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