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Article: Therapeutic effects of supervised chlorhexidine mouthrinses on untreated gingivitis

TitleTherapeutic effects of supervised chlorhexidine mouthrinses on untreated gingivitis
Authors
Issue Date1997
PublisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1
Citation
Oral Diseases, 1997, v. 3 n. 1, p. 9-18 How to Cite?
AbstractAIM: The aim of the present study was to test the presumptive therapeutic effect of chlorhexidine digluconate in a population with untreated gingivitis and presence of abundant calculus. SETTING AND STUDY DESIGN: Sixty subjects (~ mean age of 23.4) were recruited from a knitting factory in the Province of Guangdong, People's Republic of China. By applying a double-blind clinical trial design the participants were divided into two groups (Test and Control) and matched according to their mean GI scores. The Test group (n = 20) was assigned to two daily mouthrinses for 6 days per week using 0.12% chlorhexidine digluconate (Peridex®). The Control group (n = 40) rinsed twice daily with a placebo solution. All the rinsings were supervised and timed for 45 s. No attempt was made to influence the oral hygiene habits of the participants. Prior to and after 3 months of the supervised rinsing, plaque was scored using the Plaque Index system (PII), and gingivitis was assessed using the criteria of the Gingival Index system (GI). Calculus was scored according to the Calculus Surface Severity Index system (CSSI), and stain was also graded by the Discoloration Index system (DI). RESULTS: After 3 months, the Test group (n = 13) showed significant reduction in mean PII, GI and percentage of gingivial bleeding (GB%), while significant increases in mean DI were observed. The improvement in gingival health was observed at all regions with marked reduction in mean GI (from GI = 1.40 to 1.08) and GB% reduction by 24-52%. The proportion of GI = 2 was also reduced significantly from 50-36%. The Control group (n = 23) also showed a decrease in mean PII but significant increases in the mean GI and GB%. Intergroup comparison showed statistically significant differences between mean GI, percentage of gingival bleeding (GB%) and mean DI for the test and control groups after 3 months of supervised rinsing. However, there were no significant intergroup differences for mean PII. CONCLUSION: In conclusion, there was a significant effect of chlorhexidine on gingivitis, although the effect may be too limited to assure prognostic benefits in the prevention of future disease progression.
Persistent Identifierhttp://hdl.handle.net/10722/67105
ISSN
2015 Impact Factor: 2.0
2015 SCImago Journal Rankings: 0.828
References

 

DC FieldValueLanguage
dc.contributor.authorCorbet, EFen_HK
dc.contributor.authorTam, JOWen_HK
dc.contributor.authorZee, KYen_HK
dc.contributor.authorWong, MCMen_HK
dc.contributor.authorLo, ECMen_HK
dc.contributor.authorMombelli, AWen_HK
dc.contributor.authorLang, NPen_HK
dc.date.accessioned2010-09-06T05:52:00Z-
dc.date.available2010-09-06T05:52:00Z-
dc.date.issued1997en_HK
dc.identifier.citationOral Diseases, 1997, v. 3 n. 1, p. 9-18en_HK
dc.identifier.issn1354-523Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/67105-
dc.description.abstractAIM: The aim of the present study was to test the presumptive therapeutic effect of chlorhexidine digluconate in a population with untreated gingivitis and presence of abundant calculus. SETTING AND STUDY DESIGN: Sixty subjects (~ mean age of 23.4) were recruited from a knitting factory in the Province of Guangdong, People's Republic of China. By applying a double-blind clinical trial design the participants were divided into two groups (Test and Control) and matched according to their mean GI scores. The Test group (n = 20) was assigned to two daily mouthrinses for 6 days per week using 0.12% chlorhexidine digluconate (Peridex®). The Control group (n = 40) rinsed twice daily with a placebo solution. All the rinsings were supervised and timed for 45 s. No attempt was made to influence the oral hygiene habits of the participants. Prior to and after 3 months of the supervised rinsing, plaque was scored using the Plaque Index system (PII), and gingivitis was assessed using the criteria of the Gingival Index system (GI). Calculus was scored according to the Calculus Surface Severity Index system (CSSI), and stain was also graded by the Discoloration Index system (DI). RESULTS: After 3 months, the Test group (n = 13) showed significant reduction in mean PII, GI and percentage of gingivial bleeding (GB%), while significant increases in mean DI were observed. The improvement in gingival health was observed at all regions with marked reduction in mean GI (from GI = 1.40 to 1.08) and GB% reduction by 24-52%. The proportion of GI = 2 was also reduced significantly from 50-36%. The Control group (n = 23) also showed a decrease in mean PII but significant increases in the mean GI and GB%. Intergroup comparison showed statistically significant differences between mean GI, percentage of gingival bleeding (GB%) and mean DI for the test and control groups after 3 months of supervised rinsing. However, there were no significant intergroup differences for mean PII. CONCLUSION: In conclusion, there was a significant effect of chlorhexidine on gingivitis, although the effect may be too limited to assure prognostic benefits in the prevention of future disease progression.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1en_HK
dc.relation.ispartofOral Diseasesen_HK
dc.subject.meshAdolescenten_HK
dc.subject.meshAdulten_HK
dc.subject.meshChi-Square Distributionen_HK
dc.subject.meshChlorhexidine - analogs & derivatives - therapeutic useen_HK
dc.subject.meshDental Calculus - drug therapyen_HK
dc.subject.meshDental Plaque - prevention & controlen_HK
dc.subject.meshDental Plaque Indexen_HK
dc.subject.meshDouble-Blind Methoden_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGingivitis - drug therapyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMouthwashes - therapeutic useen_HK
dc.subject.meshPeriodontal Indexen_HK
dc.titleTherapeutic effects of supervised chlorhexidine mouthrinses on untreated gingivitisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1354-523X&volume=3&spage=9&epage=18&date=1997&atitle=Therapeutic+effects+of+supervised+chlorhexidine+mouthrinses+on+untreated+gingivitisen_HK
dc.identifier.emailCorbet, EF:efcorbet@hku.hken_HK
dc.identifier.emailWong, MCM:mcmwong@hkucc.hku.hken_HK
dc.identifier.emailLo, ECM:hrdplcm@hkucc.hku.hken_HK
dc.identifier.emailLang, NP:nplang@hkucc.hku.hken_HK
dc.identifier.authorityCorbet, EF=rp00005en_HK
dc.identifier.authorityWong, MCM=rp00024en_HK
dc.identifier.authorityLo, ECM=rp00015en_HK
dc.identifier.authorityLang, NP=rp00031en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid9456641-
dc.identifier.scopuseid_2-s2.0-0030953181en_HK
dc.identifier.hkuros24950en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030953181&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume3en_HK
dc.identifier.issue1en_HK
dc.identifier.spage9en_HK
dc.identifier.epage18en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridCorbet, EF=35609873200en_HK
dc.identifier.scopusauthoridTam, JOW=7102534624en_HK
dc.identifier.scopusauthoridZee, KY=6603722366en_HK
dc.identifier.scopusauthoridWong, MCM=26029250900en_HK
dc.identifier.scopusauthoridLo, ECM=7101705982en_HK
dc.identifier.scopusauthoridMombelli, AW=7006180872en_HK
dc.identifier.scopusauthoridLang, NP=7201577367en_HK

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