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Article: Efficacy of a novel lubricating system in the management of radiotherapy-related xerostomia

TitleEfficacy of a novel lubricating system in the management of radiotherapy-related xerostomia
Authors
KeywordsClinical trial
Health-related quality of life
Lubricating device
Management
Oral health
Radiotherapy
Xerostomia
Issue Date2006
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/oraloncology
Citation
Oral Oncology, 2006, v. 42 n. 8, p. 842-848 How to Cite?
AbstractA comparison was made of Oral Balance gel delivered by slow release via a novel intra-oral device versus an oral bolus of gel on the oral health condition and oral health-related quality of life (OHRQoL) in patients who had received standard head and neck irradiation for nasopharyngeal carcinoma. Twenty-two participants took part in a randomized single-blind crossover clinical study. Each treatment lasted 4 weeks with an intervening 4 weeks washout period. The GOHAI, Xerostomia Inventory and patient satisfaction measures were self-completed and oral health condition assessed objectively at baseline (week 0) and weeks 4, 8 and 12. Oral Balance gel, in bolus and slow-release forms, was effective in improving aspects of oral health, notably a reduction in oral cariogenic micro-organisms. Slow release of gel via the intra-oral device did not appear to improve OHRQoL whereas gel alone reduced the severity of xerostomia symptoms and was the treatment of choice. © 2005 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/67083
ISSN
2015 Impact Factor: 4.286
2015 SCImago Journal Rankings: 1.764
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMcMillan, ASen_HK
dc.contributor.authorPeter Tsang, CSen_HK
dc.contributor.authorWong, MCMen_HK
dc.contributor.authorKam, AYLen_HK
dc.date.accessioned2010-09-06T05:51:49Z-
dc.date.available2010-09-06T05:51:49Z-
dc.date.issued2006en_HK
dc.identifier.citationOral Oncology, 2006, v. 42 n. 8, p. 842-848en_HK
dc.identifier.issn1368-8375en_HK
dc.identifier.urihttp://hdl.handle.net/10722/67083-
dc.description.abstractA comparison was made of Oral Balance gel delivered by slow release via a novel intra-oral device versus an oral bolus of gel on the oral health condition and oral health-related quality of life (OHRQoL) in patients who had received standard head and neck irradiation for nasopharyngeal carcinoma. Twenty-two participants took part in a randomized single-blind crossover clinical study. Each treatment lasted 4 weeks with an intervening 4 weeks washout period. The GOHAI, Xerostomia Inventory and patient satisfaction measures were self-completed and oral health condition assessed objectively at baseline (week 0) and weeks 4, 8 and 12. Oral Balance gel, in bolus and slow-release forms, was effective in improving aspects of oral health, notably a reduction in oral cariogenic micro-organisms. Slow release of gel via the intra-oral device did not appear to improve OHRQoL whereas gel alone reduced the severity of xerostomia symptoms and was the treatment of choice. © 2005 Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/oraloncologyen_HK
dc.relation.ispartofOral Oncologyen_HK
dc.subjectClinical trialen_HK
dc.subjectHealth-related quality of lifeen_HK
dc.subjectLubricating deviceen_HK
dc.subjectManagementen_HK
dc.subjectOral healthen_HK
dc.subjectRadiotherapyen_HK
dc.subjectXerostomiaen_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshCross-Over Studiesen_HK
dc.subject.meshDelayed-Action Preparationsen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGelsen_HK
dc.subject.meshHealth Status Indicatorsen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNasopharyngeal Neoplasms - radiotherapyen_HK
dc.subject.meshPatient Satisfactionen_HK
dc.subject.meshPolymers - administration & dosageen_HK
dc.subject.meshQuality of Lifeen_HK
dc.subject.meshRadiation Injuries - etiology - physiopathology - therapyen_HK
dc.subject.meshSaliva, Artificial - administration & dosageen_HK
dc.subject.meshSalivationen_HK
dc.subject.meshSeverity of Illness Indexen_HK
dc.subject.meshSingle-Blind Methoden_HK
dc.subject.meshTreatment Outcomeen_HK
dc.subject.meshXerostomia - etiology - physiopathology - therapyen_HK
dc.titleEfficacy of a novel lubricating system in the management of radiotherapy-related xerostomiaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1368-8375&volume=42&issue=8&spage=842&epage=8&date=2006&atitle=Efficacy+of+a+novel+lubricating+system+in+the+management+of+radiotherapy-related+xerostomiaen_HK
dc.identifier.emailMcMillan, AS: annemcmillan@hku.hken_HK
dc.identifier.emailPeter Tsang, CS: csptsang@hkucc.hku.hken_HK
dc.identifier.emailWong, MCM: mcmwong@hkucc.hku.hken_HK
dc.identifier.authorityMcMillan, AS=rp00014en_HK
dc.identifier.authorityPeter Tsang, CS=rp00026en_HK
dc.identifier.authorityWong, MCM=rp00024en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.oraloncology.2005.12.003en_HK
dc.identifier.pmid16455288-
dc.identifier.scopuseid_2-s2.0-33748111265en_HK
dc.identifier.hkuros135691en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33748111265&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume42en_HK
dc.identifier.issue8en_HK
dc.identifier.spage842en_HK
dc.identifier.epage848en_HK
dc.identifier.eissn1879-0593-
dc.identifier.isiWOS:000241088500013-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.f100014224-
dc.identifier.scopusauthoridMcMillan, AS=7102843317en_HK
dc.identifier.scopusauthoridPeter Tsang, CS=7202936002en_HK
dc.identifier.scopusauthoridWong, MCM=26029250900en_HK
dc.identifier.scopusauthoridKam, AYL=8698062600en_HK

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