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Article: Evaluation of functional dynamics during osseointegration and regeneration associated with oral implants
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TitleEvaluation of functional dynamics during osseointegration and regeneration associated with oral implants
 
AuthorsChang, PC3 4 2
Lang, NP1
Giannobile, WV3 2
 
Issue Date2010
 
PublisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLR
 
CitationClinical Oral Implants Research, 2010, v. 21 n. 1, p. 1-12 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1600-0501.2009.01826.x
 
AbstractObjectives: The aim of this paper is to review current investigations on functional assessments of osseointegration and assess correlations to the peri-implant structure. Material and methods: The literature was electronically searched for studies of promoting dental implant osseointegration, functional assessments of implant stability, and finite element (FE) analyses in the field of implant dentistry, and any references regarding biological events during osseointegration were also cited as background information. Results: Osseointegration involves a cascade of protein and cell apposition, vascular invasion, de novo bone formation and maturation to achieve the primary and secondary dental implant stability. This process may be accelerated by alteration of the implant surface roughness, developing a biomimetric interface, or local delivery of growth-promoting factors. The current available pre-clinical and clinical biomechanical assessments demonstrated a variety of correlations to the peri-implant structural parameters, and functionally integrated peri-implant structure through FE optimization can offer strong correlation to the interfacial biomechanics. Conclusions: The progression of osseointegration may be accelerated by alteration of the implant interface as well as growth factor applications, and functional integration of peri-implant structure may be feasible to predict the implant function during osseointegration. More research in this field is still needed. © 2009 John Wiley & Sons A/S.
 
ISSN0905-7161
2012 Impact Factor: 3.433
2012 SCImago Journal Rankings: 1.154
 
DOIhttp://dx.doi.org/10.1111/j.1600-0501.2009.01826.x
 
PubMed Central IDPMC2808201
 
ISI Accession Number IDWOS:000272835900001
Funding AgencyGrant Number
AO Foundation Research Advisory Council
NIH/NIDCRDE 13397
Funding Information:

Funding: This study was supported by the AO Foundation Research Advisory Council and NIH/NIDCR DE 13397.

 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorChang, PC
 
dc.contributor.authorLang, NP
 
dc.contributor.authorGiannobile, WV
 
dc.date.accessioned2010-09-06T05:51:20Z
 
dc.date.available2010-09-06T05:51:20Z
 
dc.date.issued2010
 
dc.description.abstractObjectives: The aim of this paper is to review current investigations on functional assessments of osseointegration and assess correlations to the peri-implant structure. Material and methods: The literature was electronically searched for studies of promoting dental implant osseointegration, functional assessments of implant stability, and finite element (FE) analyses in the field of implant dentistry, and any references regarding biological events during osseointegration were also cited as background information. Results: Osseointegration involves a cascade of protein and cell apposition, vascular invasion, de novo bone formation and maturation to achieve the primary and secondary dental implant stability. This process may be accelerated by alteration of the implant surface roughness, developing a biomimetric interface, or local delivery of growth-promoting factors. The current available pre-clinical and clinical biomechanical assessments demonstrated a variety of correlations to the peri-implant structural parameters, and functionally integrated peri-implant structure through FE optimization can offer strong correlation to the interfacial biomechanics. Conclusions: The progression of osseointegration may be accelerated by alteration of the implant interface as well as growth factor applications, and functional integration of peri-implant structure may be feasible to predict the implant function during osseointegration. More research in this field is still needed. © 2009 John Wiley & Sons A/S.
 
dc.description.natureLink_to_OA_fulltext
 
dc.identifier.citationClinical Oral Implants Research, 2010, v. 21 n. 1, p. 1-12 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1600-0501.2009.01826.x
 
dc.identifier.citeulike6422459
 
dc.identifier.doihttp://dx.doi.org/10.1111/j.1600-0501.2009.01826.x
 
dc.identifier.epage12
 
dc.identifier.hkuros169089
 
dc.identifier.isiWOS:000272835900001
Funding AgencyGrant Number
AO Foundation Research Advisory Council
NIH/NIDCRDE 13397
Funding Information:

Funding: This study was supported by the AO Foundation Research Advisory Council and NIH/NIDCR DE 13397.

 
dc.identifier.issn0905-7161
2012 Impact Factor: 3.433
2012 SCImago Journal Rankings: 1.154
 
dc.identifier.issue1
 
dc.identifier.openurl
 
dc.identifier.pmcidPMC2808201
 
dc.identifier.pmid20070743
 
dc.identifier.scopuseid_2-s2.0-72949099261
 
dc.identifier.spage1
 
dc.identifier.urihttp://hdl.handle.net/10722/67026
 
dc.identifier.volume21
 
dc.languageeng
 
dc.publisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLR
 
dc.publisher.placeUnited States
 
dc.relation.ispartofClinical Oral Implants Research
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshAnimals
 
dc.subject.meshBiomechanics
 
dc.subject.meshDental Implantation, Endosseous
 
dc.subject.meshDental Implants
 
dc.subject.meshFinite Element Analysis
 
dc.subject.meshHumans
 
dc.subject.meshIntercellular Signaling Peptides and Proteins - pharmacology
 
dc.subject.meshOsseointegration - physiology
 
dc.subject.meshSurface Properties
 
dc.titleEvaluation of functional dynamics during osseointegration and regeneration associated with oral implants
 
dc.typeArticle
 
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Author Affiliations
  1. The University of Hong Kong
  2. University Michigan Ann Arbor
  3. University of Michigan School of Dentistry
  4. National University of Singapore