File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: In vitro susceptibility of Candida albicans isolates from apical and marginal periodontitis to common antifungal agents

TitleIn vitro susceptibility of Candida albicans isolates from apical and marginal periodontitis to common antifungal agents
Authors
Issue Date2000
PublisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/OMI
Citation
Oral Microbiology And Immunology, 2000, v. 15 n. 4, p. 245-248 How to Cite?
AbstractThe susceptibility of a total of 70 Candida albicans strains to five common antifungal agents was determined. Thirty-five of the strains were isolated from persistent cases of apical periodontitis and 35 from cases of marginal periodontitis. The susceptibility of the strains to amphotericin B, 5-fluorocytosine and three azoles: fluconazole, miconazole and clotrimazole, was tested. The antifungal agents and yeast inoculums were prepared according to the NCCLS (National Committee for Clinical Laboratory Standards) recommendations. The yeasts were incubated with ten different concentrations of antifungal agents at 35°C for 48 h. Yeast growth was measured spectrophotometrically. All strains from both isolation sources were susceptible to low concentrations of amphotericin B and 5-fluorocytosine, whereas the susceptibility to the three azoles varied, and three of the strains showed azole crossresistance. These findings are in agreement with recent reports of increased azole resistance in Candida species in general and suggest the possibility that the oral cavity may act as a reservoir of resistant yeast isolates in systemic infections.
Persistent Identifierhttp://hdl.handle.net/10722/66923
ISSN
2011 Impact Factor: 2.807
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWaltimo, TMTen_HK
dc.contributor.authorØrstavik, Den_HK
dc.contributor.authorMeurman, JHen_HK
dc.contributor.authorSamaranayake, LPen_HK
dc.contributor.authorHaapasalo, MPPen_HK
dc.date.accessioned2010-09-06T05:50:29Z-
dc.date.available2010-09-06T05:50:29Z-
dc.date.issued2000en_HK
dc.identifier.citationOral Microbiology And Immunology, 2000, v. 15 n. 4, p. 245-248en_HK
dc.identifier.issn0902-0055en_HK
dc.identifier.urihttp://hdl.handle.net/10722/66923-
dc.description.abstractThe susceptibility of a total of 70 Candida albicans strains to five common antifungal agents was determined. Thirty-five of the strains were isolated from persistent cases of apical periodontitis and 35 from cases of marginal periodontitis. The susceptibility of the strains to amphotericin B, 5-fluorocytosine and three azoles: fluconazole, miconazole and clotrimazole, was tested. The antifungal agents and yeast inoculums were prepared according to the NCCLS (National Committee for Clinical Laboratory Standards) recommendations. The yeasts were incubated with ten different concentrations of antifungal agents at 35°C for 48 h. Yeast growth was measured spectrophotometrically. All strains from both isolation sources were susceptible to low concentrations of amphotericin B and 5-fluorocytosine, whereas the susceptibility to the three azoles varied, and three of the strains showed azole crossresistance. These findings are in agreement with recent reports of increased azole resistance in Candida species in general and suggest the possibility that the oral cavity may act as a reservoir of resistant yeast isolates in systemic infections.en_HK
dc.languageengen_HK
dc.publisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/OMIen_HK
dc.relation.ispartofOral Microbiology and Immunologyen_HK
dc.subject.meshAmphotericin B - pharmacologyen_HK
dc.subject.meshAntifungal Agents - pharmacologyen_HK
dc.subject.meshCandida albicans - drug effectsen_HK
dc.subject.meshClotrimazole - pharmacologyen_HK
dc.subject.meshFluconazole - pharmacologyen_HK
dc.subject.meshFlucytosine - pharmacologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMiconazole - pharmacologyen_HK
dc.subject.meshMicrobial Sensitivity Testsen_HK
dc.subject.meshPeriapical Periodontitis - microbiologyen_HK
dc.subject.meshPeriodontitis - microbiologyen_HK
dc.titleIn vitro susceptibility of Candida albicans isolates from apical and marginal periodontitis to common antifungal agentsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0902-0055&volume=15&spage=245&epage=248&date=2000&atitle=In+vitro+susceptibility+of+Candida+albicans+isolates+from+apical+and+marginal+periodontitis+to+common+antifungal+agentsen_HK
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_HK
dc.identifier.authoritySamaranayake, LP=rp00023en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid11154410-
dc.identifier.scopuseid_2-s2.0-0033939867en_HK
dc.identifier.hkuros52009en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033939867&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume15en_HK
dc.identifier.issue4en_HK
dc.identifier.spage245en_HK
dc.identifier.epage248en_HK
dc.identifier.isiWOS:000088204700006-
dc.publisher.placeDenmarken_HK
dc.identifier.scopusauthoridWaltimo, TMT=7004089148en_HK
dc.identifier.scopusauthoridØrstavik, D=7004417532en_HK
dc.identifier.scopusauthoridMeurman, JH=7006469347en_HK
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_HK
dc.identifier.scopusauthoridHaapasalo, MPP=7003569249en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats