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- Publisher Website: 10.1111/j.1834-7819.2009.01162.x
- Scopus: eid_2-s2.0-77949371604
- PMID: 20415935
- WOS: WOS:000272160600012
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Article: Pre-emptive ibuprofen arginate in third molar surgery: A double-blind randomized controlled crossover clinical trial
Title | Pre-emptive ibuprofen arginate in third molar surgery: A double-blind randomized controlled crossover clinical trial | ||||
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Authors | |||||
Keywords | Ibuprofen arginate Pre-emptive Third molars | ||||
Issue Date | 2009 | ||||
Publisher | Wiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0045-0421 | ||||
Citation | Australian Dental Journal, 2009, v. 54 n. 4, p. 355-360 How to Cite? | ||||
Abstract | Background: This study evaluated the effectiveness of 400 mg ibuprofen arginate either as a pre-emptive (PRE group) or postoperative (POST group) analgesic using a common dental pain model. Methods: A randomized double-blind crossover clinical trial involving a series of consecutive patients admitted for bilateral third molar surgery. Results were analysed according to the self-reported pain score and the pattern of rescue medication taken. Results: The mean pain score ranged from 0.73 to 1.60 for the PRE group and 0.47 to 1.41 for the POST group among 30 included subjects. The mean time point when first rescue medication taken was 7.3 hours and 8.3 hours postoperative, respectively. Nine patients (30 per cent) in the PRE group and 12 patients (40 per cent) in the POST group took no rescue medication. There was no statistically significant difference for all parameters between groups, while a majority (53 per cent) found the drug "good" to "excellent" in both groups. Conclusions: Ibuprofen arginate may be considered effective in reducing surgically induced moderate to severe pain when administered either pre-operatively or postoperatively due to the reported relatively low pain score, less consumption of rescue medication, delayed onset of pain, good number of pain-free patients and a high rating in the global assessment score. © 2009 Australian Dental Association. | ||||
Persistent Identifier | http://hdl.handle.net/10722/66774 | ||||
ISSN | 2021 Impact Factor: 2.259 2020 SCImago Journal Rankings: 0.701 | ||||
ISI Accession Number ID |
Funding Information: Thanks to Zambon (HK) for financial support for this clinical trail. | ||||
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lau, SL | en_HK |
dc.contributor.author | Chow, RLK | en_HK |
dc.contributor.author | Yeung, RWK | en_HK |
dc.contributor.author | Samman, N | en_HK |
dc.date.accessioned | 2010-09-06T05:49:14Z | - |
dc.date.available | 2010-09-06T05:49:14Z | - |
dc.date.issued | 2009 | en_HK |
dc.identifier.citation | Australian Dental Journal, 2009, v. 54 n. 4, p. 355-360 | en_HK |
dc.identifier.issn | 0045-0421 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/66774 | - |
dc.description.abstract | Background: This study evaluated the effectiveness of 400 mg ibuprofen arginate either as a pre-emptive (PRE group) or postoperative (POST group) analgesic using a common dental pain model. Methods: A randomized double-blind crossover clinical trial involving a series of consecutive patients admitted for bilateral third molar surgery. Results were analysed according to the self-reported pain score and the pattern of rescue medication taken. Results: The mean pain score ranged from 0.73 to 1.60 for the PRE group and 0.47 to 1.41 for the POST group among 30 included subjects. The mean time point when first rescue medication taken was 7.3 hours and 8.3 hours postoperative, respectively. Nine patients (30 per cent) in the PRE group and 12 patients (40 per cent) in the POST group took no rescue medication. There was no statistically significant difference for all parameters between groups, while a majority (53 per cent) found the drug "good" to "excellent" in both groups. Conclusions: Ibuprofen arginate may be considered effective in reducing surgically induced moderate to severe pain when administered either pre-operatively or postoperatively due to the reported relatively low pain score, less consumption of rescue medication, delayed onset of pain, good number of pain-free patients and a high rating in the global assessment score. © 2009 Australian Dental Association. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Wiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0045-0421 | en_HK |
dc.relation.ispartof | Australian Dental Journal | en_HK |
dc.rights | The definitive version is available at www3.interscience.wiley.com | - |
dc.subject | Ibuprofen arginate | en_HK |
dc.subject | Pre-emptive | en_HK |
dc.subject | Third molars | en_HK |
dc.subject.mesh | Analgesics, Non-Narcotic - administration and dosage | - |
dc.subject.mesh | Arginine - administration and dosage | - |
dc.subject.mesh | Molar, Third - surgery | - |
dc.subject.mesh | Pain, Postoperative - prevention and control | - |
dc.subject.mesh | Tooth Extraction | - |
dc.title | Pre-emptive ibuprofen arginate in third molar surgery: A double-blind randomized controlled crossover clinical trial | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0045-0421&volume=54&issue=4&spage=355&epage=360&date=2009&atitle=Pre-emptive+ibuprofen+arginate+in+third+molar+surgery:+a+double-blind+randomized+controlled+crossover+clinical+trial | en_HK |
dc.identifier.email | Samman, N:nsamman@hkucc.hku.hk | en_HK |
dc.identifier.authority | Samman, N=rp00021 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1111/j.1834-7819.2009.01162.x | en_HK |
dc.identifier.pmid | 20415935 | - |
dc.identifier.scopus | eid_2-s2.0-77949371604 | en_HK |
dc.identifier.hkuros | 168482 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-77949371604&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 54 | en_HK |
dc.identifier.issue | 4 | en_HK |
dc.identifier.spage | 355 | en_HK |
dc.identifier.epage | 360 | en_HK |
dc.identifier.eissn | 1834-7819 | - |
dc.identifier.isi | WOS:000272160600012 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Lau, SL=36600672300 | en_HK |
dc.identifier.scopusauthorid | Chow, RLK=14621379900 | en_HK |
dc.identifier.scopusauthorid | Yeung, RWK=7102833345 | en_HK |
dc.identifier.scopusauthorid | Samman, N=7006413627 | en_HK |
dc.identifier.issnl | 0045-0421 | - |