File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: The impact of diabetes on the success of dental implants and periodontal healing

TitleThe impact of diabetes on the success of dental implants and periodontal healing
Authors
KeywordsBone resorption
Chlorohexidine mouthwash
Dental implant
Diabetes mellitus
Periodontal healing
Tooth mobility
Issue Date2009
PublisherAcademic Journals. The Journal's web site is located at http://www.academicjournals.org/AJB/index.htm
Citation
African Journal Of Biotechnology, 2009, v. 8 n. 19, p. 5122-5127 How to Cite?
AbstractDental implant is one of the restorative methods to replace missing teeth. As implants are directly anchored into bones, they provide stability, a more natural appearance, and minimize the risk of bone resorption and atrophy. However, studies found that diabetes mellitus patients had a slower healing process after surgery because of the reduction of vascular supply due to microangiopathies, decreased host defense, formation of advanced glycation end-products (AGEs), reduction of collagen production and increased collagenase activity. Diabetes mellitus patients may pose contraindications to dental implants. As a result of that, dental implantation failure rate in diabetic patients is much higher than that in non-diabetic patients. In this clinical experiment, we compared the amount of blood cells, and cytokines production 24 h post implantations, and the implant mobility 90 days post-surgery between controlled type 2 diabetic patients and the non-diabetic patients. It was aimed to investigate the suitability of diabetic patients to have dental implants and the efficacy of the amount of dental implants related to the success rates. 138 patients with type 2 diabetics and 140 healthy subjects, who had one to three adjacent edentulous spaces, were selected. Dental implantation surgeries were performed under local anesthesia. Wounds were sutured and all subjects were given 0.2% chlorohexidine mouthwash for 14 days. Complete blood picture and cytokines production were assayed before operation, as well as on days 1, 2, and 5 after implantation. Implant mobility and periodontal wound healing were monitored once in a fortnight up to 90 days. There were no statistically significant differences in the production of cytokines. In 138 diabetic patients, 255 implants were presented with second degree mobility 90 days after surgery while the same was demonstrated in 48 out of 346 implants from the healthy subjects. These implants were considered failures and were extracted. Implant failure in diabetics was significantly greater than that in non-diabetics when multiple adjoining implants were placed. © 2009 Academic Journals.
Persistent Identifierhttp://hdl.handle.net/10722/66684
ISSN
2010 Impact Factor: 0.573
2015 SCImago Journal Rankings: 0.295
References

 

DC FieldValueLanguage
dc.contributor.authorLoo, WTYen_HK
dc.contributor.authorJin, LJen_HK
dc.contributor.authorCheung, MNBen_HK
dc.contributor.authorWang, Men_HK
dc.date.accessioned2010-09-06T05:48:27Z-
dc.date.available2010-09-06T05:48:27Z-
dc.date.issued2009en_HK
dc.identifier.citationAfrican Journal Of Biotechnology, 2009, v. 8 n. 19, p. 5122-5127en_HK
dc.identifier.issn1684-5315en_HK
dc.identifier.urihttp://hdl.handle.net/10722/66684-
dc.description.abstractDental implant is one of the restorative methods to replace missing teeth. As implants are directly anchored into bones, they provide stability, a more natural appearance, and minimize the risk of bone resorption and atrophy. However, studies found that diabetes mellitus patients had a slower healing process after surgery because of the reduction of vascular supply due to microangiopathies, decreased host defense, formation of advanced glycation end-products (AGEs), reduction of collagen production and increased collagenase activity. Diabetes mellitus patients may pose contraindications to dental implants. As a result of that, dental implantation failure rate in diabetic patients is much higher than that in non-diabetic patients. In this clinical experiment, we compared the amount of blood cells, and cytokines production 24 h post implantations, and the implant mobility 90 days post-surgery between controlled type 2 diabetic patients and the non-diabetic patients. It was aimed to investigate the suitability of diabetic patients to have dental implants and the efficacy of the amount of dental implants related to the success rates. 138 patients with type 2 diabetics and 140 healthy subjects, who had one to three adjacent edentulous spaces, were selected. Dental implantation surgeries were performed under local anesthesia. Wounds were sutured and all subjects were given 0.2% chlorohexidine mouthwash for 14 days. Complete blood picture and cytokines production were assayed before operation, as well as on days 1, 2, and 5 after implantation. Implant mobility and periodontal wound healing were monitored once in a fortnight up to 90 days. There were no statistically significant differences in the production of cytokines. In 138 diabetic patients, 255 implants were presented with second degree mobility 90 days after surgery while the same was demonstrated in 48 out of 346 implants from the healthy subjects. These implants were considered failures and were extracted. Implant failure in diabetics was significantly greater than that in non-diabetics when multiple adjoining implants were placed. © 2009 Academic Journals.en_HK
dc.languageengen_HK
dc.publisherAcademic Journals. The Journal's web site is located at http://www.academicjournals.org/AJB/index.htmen_HK
dc.relation.ispartofAfrican Journal of Biotechnologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectBone resorptionen_HK
dc.subjectChlorohexidine mouthwashen_HK
dc.subjectDental implanten_HK
dc.subjectDiabetes mellitusen_HK
dc.subjectPeriodontal healingen_HK
dc.subjectTooth mobilityen_HK
dc.titleThe impact of diabetes on the success of dental implants and periodontal healingen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1684-5315&volume=8&issue=19&spage=5122&epage=5127&date=2009&atitle=The+impact+of+diabetes+on+the+success+of+dental+implants+and+periodontal+healingen_HK
dc.identifier.emailJin, LJ:ljjin@hkucc.hku.hken_HK
dc.identifier.authorityJin, LJ=rp00028en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.scopuseid_2-s2.0-70350457756en_HK
dc.identifier.hkuros169275en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-70350457756&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume8en_HK
dc.identifier.issue19en_HK
dc.identifier.spage5122en_HK
dc.identifier.epage5127en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLoo, WTY=7003567474en_HK
dc.identifier.scopusauthoridJin, LJ=7403328850en_HK
dc.identifier.scopusauthoridCheung, MNB=7201897548en_HK
dc.identifier.scopusauthoridWang, M=36080215600en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats