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Article: A prospective study of the impact of nasopharyngeal cancer and radiotherapy on the psychosocial condition of Chinese patients

TitleA prospective study of the impact of nasopharyngeal cancer and radiotherapy on the psychosocial condition of Chinese patients
Authors
KeywordsCourse
Nasopharyngeal cancer
Psychological response
Psychosocial impact
Radiotherapy
Issue Date2007
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741
Citation
Cancer, 2007, v. 109 n. 7, p. 1344-1354 How to Cite?
AbstractBACKGROUND. Radiotherapy (RT) promises optimistic results in the treatment of nasopharyngeal cancer (NPC). The objective of the current study was to map out prospectively the impact of NPC and RT on patients from diagnosis to 1 year posttreatment. METHODS. For this study, 67 Chinese patients (46 men and 21 women) with newly diagnosed stage I or II NPC who received primary RT were recruited. Physical and psychosocial adjustments were measured by using the Rotterdam Symptom Checklist, Beck Anxiety Inventory, Beck Depression Inventory, Perceived Stress Scale, and the 36-item Short-Form Health Survey (SF-36). Semistructured clinical interviews were conducted at bimonthly intervals from pre-RT to 1 year post-RT. RESULTS. Physical and psychosocial adjustments were poorest from pre-RT to the end of RT. Rapid improvements in all areas were noted in the first 2 months post-RT and reached a plateau at around the 6th month. At 1 year, except for physical symptoms and perceived stress, patient measures recovered to their pre-RT levels. At 1 year, patients had more physical complaints (P < .001) but less perceived stress (P = .002). The percentage of patients who expressed fear of dying dropped from 28% pre-RT to 2% at 1 year. However, patients who expressed "fear of the worst happening" increased from 51% pre-RT to 57% at 1 year. CONCLUSIONS. Different periods in treatment of NPC imposed different psychosocial demands on patients. The current results indicated that the period from diagnosis to 2-month post-RT was a high-risk period both physically and emotionally. After treatment, most patients showed resilience despite persistent side effects of RT and successfully resumed their pretreatment level of functioning by the end of the year. Despite resuming a normal or near-normal living, patients still noted a subdued fear of recurrence. © 2007 American Cancer Society.
Persistent Identifierhttp://hdl.handle.net/10722/66672
ISSN
2014 Impact Factor: 4.889
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLee, PWHen_HK
dc.contributor.authorKwan, TTCen_HK
dc.contributor.authorKwong, DLWen_HK
dc.contributor.authorSham, JSTen_HK
dc.contributor.authorPow, EHNen_HK
dc.contributor.authorMcMillan, ASen_HK
dc.contributor.authorAu, GKHen_HK
dc.date.accessioned2010-09-06T05:48:20Z-
dc.date.available2010-09-06T05:48:20Z-
dc.date.issued2007en_HK
dc.identifier.citationCancer, 2007, v. 109 n. 7, p. 1344-1354en_HK
dc.identifier.issn0008-543Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/66672-
dc.description.abstractBACKGROUND. Radiotherapy (RT) promises optimistic results in the treatment of nasopharyngeal cancer (NPC). The objective of the current study was to map out prospectively the impact of NPC and RT on patients from diagnosis to 1 year posttreatment. METHODS. For this study, 67 Chinese patients (46 men and 21 women) with newly diagnosed stage I or II NPC who received primary RT were recruited. Physical and psychosocial adjustments were measured by using the Rotterdam Symptom Checklist, Beck Anxiety Inventory, Beck Depression Inventory, Perceived Stress Scale, and the 36-item Short-Form Health Survey (SF-36). Semistructured clinical interviews were conducted at bimonthly intervals from pre-RT to 1 year post-RT. RESULTS. Physical and psychosocial adjustments were poorest from pre-RT to the end of RT. Rapid improvements in all areas were noted in the first 2 months post-RT and reached a plateau at around the 6th month. At 1 year, except for physical symptoms and perceived stress, patient measures recovered to their pre-RT levels. At 1 year, patients had more physical complaints (P < .001) but less perceived stress (P = .002). The percentage of patients who expressed fear of dying dropped from 28% pre-RT to 2% at 1 year. However, patients who expressed "fear of the worst happening" increased from 51% pre-RT to 57% at 1 year. CONCLUSIONS. Different periods in treatment of NPC imposed different psychosocial demands on patients. The current results indicated that the period from diagnosis to 2-month post-RT was a high-risk period both physically and emotionally. After treatment, most patients showed resilience despite persistent side effects of RT and successfully resumed their pretreatment level of functioning by the end of the year. Despite resuming a normal or near-normal living, patients still noted a subdued fear of recurrence. © 2007 American Cancer Society.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741en_HK
dc.relation.ispartofCanceren_HK
dc.rightsCancer. Copyright © John Wiley & Sons, Inc.en_HK
dc.subjectCourseen_HK
dc.subjectNasopharyngeal canceren_HK
dc.subjectPsychological responseen_HK
dc.subjectPsychosocial impacten_HK
dc.subjectRadiotherapyen_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshCarcinoma, Squamous Cell - psychology - radiotherapyen_HK
dc.subject.meshChina - epidemiologyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshNasopharyngeal Neoplasms - psychology - radiotherapyen_HK
dc.subject.meshPatient Satisfactionen_HK
dc.subject.meshProspective Studiesen_HK
dc.subject.meshQuality of Life - psychologyen_HK
dc.titleA prospective study of the impact of nasopharyngeal cancer and radiotherapy on the psychosocial condition of Chinese patientsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0008-543X&volume=109&spage=1344&epage=54&date=2007&atitle=A+prospective+study+of+the+impact+of+nasopharyngeal+cancer+and+radiotherapy+on+the+psychosocial+condition+of+Chinese+patients.en_HK
dc.identifier.emailKwong, DLW: dlwkwong@hku.hken_HK
dc.identifier.emailPow, EHN: ehnpow@hku.hken_HK
dc.identifier.emailMcMillan, AS: annemcmillan@hku.hken_HK
dc.identifier.authorityKwong, DLW=rp00414en_HK
dc.identifier.authorityPow, EHN=rp00030en_HK
dc.identifier.authorityMcMillan, AS=rp00014en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1002/cncr.22539en_HK
dc.identifier.pmid17326045en_HK
dc.identifier.scopuseid_2-s2.0-33947528211en_HK
dc.identifier.hkuros129561en_HK
dc.identifier.hkuros212281-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33947528211&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume109en_HK
dc.identifier.issue7en_HK
dc.identifier.spage1344en_HK
dc.identifier.epage1354en_HK
dc.identifier.eissn1097-0142-
dc.identifier.isiWOS:000245229000015-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLee, PWH=7406120357en_HK
dc.identifier.scopusauthoridKwan, TTC=16063821800en_HK
dc.identifier.scopusauthoridKwong, DLW=15744231600en_HK
dc.identifier.scopusauthoridSham, JST=24472255400en_HK
dc.identifier.scopusauthoridPow, EHN=6603825799en_HK
dc.identifier.scopusauthoridMcMillan, AS=7102843317en_HK
dc.identifier.scopusauthoridAu, GKH=7003748615en_HK

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