File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: The effect of crude extract from Radix Dipsaci on bone in mice

TitleThe effect of crude extract from Radix Dipsaci on bone in mice
Authors
KeywordsBone formation
Dipsacus asperoides
Radix Dipsaci
Traditional Chinese Medicine
Issue Date2007
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/12567
Citation
Phytotherapy Research, 2007, v. 21 n. 6, p. 596-598 How to Cite?
AbstractRadix Dipsaci is used in China for the treatment of bone fractures and other bone diseases. The aim of the study was to assess the systemic effect of Radix Dipsaci consumption on bone histomorphology. Twenty eight-week-old male BALB/c mice were divided into two groups. In the control group, ten mice were daily fed with distilled water. In the Radix Dipsaci group, ten mice were daily fed with distilled water mixed with crude Radix Dipsaci extract. The mice were kept for 5 weeks and were then killed. Using microcomputed tomography, 20 microtomographic slices with an increment of 0.25 mm were acquired to cover the proximal end of the left tibia of each mouse. Quantitative morphometry of the bone structure was performed. Histological sections of the region of micro-tomographic slices were prepared. The results showed that the consumption of Radix Dipsaci extract caused a 4.50% increase in bone volume/tissue volume ratio. The bone trabeculae increased by 11.82% in number so that the bone density was increased. To conclude, Radix Dipsaci extract taken orally increased bone density and altered bone histomorphology. Copyright © 2007 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/66660
ISSN
2015 Impact Factor: 2.694
2015 SCImago Journal Rankings: 0.842
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, RWKen_HK
dc.contributor.authorRabie, ABMen_HK
dc.contributor.authorHägg, EUOen_HK
dc.date.accessioned2010-09-06T05:48:14Z-
dc.date.available2010-09-06T05:48:14Z-
dc.date.issued2007en_HK
dc.identifier.citationPhytotherapy Research, 2007, v. 21 n. 6, p. 596-598en_HK
dc.identifier.issn0951-418Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/66660-
dc.description.abstractRadix Dipsaci is used in China for the treatment of bone fractures and other bone diseases. The aim of the study was to assess the systemic effect of Radix Dipsaci consumption on bone histomorphology. Twenty eight-week-old male BALB/c mice were divided into two groups. In the control group, ten mice were daily fed with distilled water. In the Radix Dipsaci group, ten mice were daily fed with distilled water mixed with crude Radix Dipsaci extract. The mice were kept for 5 weeks and were then killed. Using microcomputed tomography, 20 microtomographic slices with an increment of 0.25 mm were acquired to cover the proximal end of the left tibia of each mouse. Quantitative morphometry of the bone structure was performed. Histological sections of the region of micro-tomographic slices were prepared. The results showed that the consumption of Radix Dipsaci extract caused a 4.50% increase in bone volume/tissue volume ratio. The bone trabeculae increased by 11.82% in number so that the bone density was increased. To conclude, Radix Dipsaci extract taken orally increased bone density and altered bone histomorphology. Copyright © 2007 John Wiley & Sons, Ltd.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/12567en_HK
dc.relation.ispartofPhytotherapy Researchen_HK
dc.rightsPhytotherapy Research. Copyright © John Wiley & Sons Ltd.en_HK
dc.subjectBone formationen_HK
dc.subjectDipsacus asperoidesen_HK
dc.subjectRadix Dipsacien_HK
dc.subjectTraditional Chinese Medicineen_HK
dc.subject.meshAngiosperms - chemistryen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshBone Density - drug effectsen_HK
dc.subject.meshBone and Bones - drug effects - metabolism - radiographyen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiceen_HK
dc.subject.meshMice, Inbred BALB Cen_HK
dc.subject.meshPlant Extracts - pharmacologyen_HK
dc.subject.meshTomography, X-Ray Computeden_HK
dc.titleThe effect of crude extract from Radix Dipsaci on bone in miceen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0951-418X&volume=21&spage=596&epage=598&date=2007&atitle=The+Effect+of+Crude+Extract+from+Radix+Dipsaci+on+Bone+in+Miceen_HK
dc.identifier.emailWong, RWK: fyoung@hku.hken_HK
dc.identifier.emailRabie, ABM: rabie@hku.hken_HK
dc.identifier.emailHägg, EUO: euohagg@hkusua.hku.hken_HK
dc.identifier.authorityWong, RWK=rp00038en_HK
dc.identifier.authorityRabie, ABM=rp00029en_HK
dc.identifier.authorityHägg, EUO=rp00020en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/ptr.2126en_HK
dc.identifier.pmid17380551-
dc.identifier.scopuseid_2-s2.0-34250337647en_HK
dc.identifier.hkuros128817en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34250337647&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume21en_HK
dc.identifier.issue6en_HK
dc.identifier.spage596en_HK
dc.identifier.epage598en_HK
dc.identifier.isiWOS:000247051800020-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, RWK=7402127170en_HK
dc.identifier.scopusauthoridRabie, ABM=7007172734en_HK
dc.identifier.scopusauthoridHägg, EUO=7006790279en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats