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Article: Patient-centred outcome measures for oral mucosal disease are sensitive to treatment

TitlePatient-centred outcome measures for oral mucosal disease are sensitive to treatment
Authors
Issue Date2003
PublisherChurchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/ijom
Citation
International Journal Of Oral And Maxillofacial Surgery, 2003, v. 32 n. 3, p. 334-336 How to Cite?
AbstractThe aim of this study was to evaluate the sensitivity of two patient-centred outcome measures to the topical application of a corticosteroid (betamethasone) in the treatment of oral lichen planus (OLP). Forty-eight patients with clinical and histological features of OLP were recruited to take part in a 6-week study of the effectiveness of topical betamethasone for the treatment of symptomatic OLP. Participants completed a questionnaire incorporating the 16-item UK Oral Health Related Quality Of Life measure (OHQOL- UK©) and the 14-item Oral Health Impact Profile (OHIP-14), rated their pain on 'global' and visual analogue scales (VAS) and underwent an oral examination, at the start and end of the trial. Four (8%) patients failed to complete the study. The clinical signs of OLP had improved for half (22) of the patients following treatment. Twenty-nine (66%) reported that their oral pain had reduced ('global' scale). More objectively, there were significant differences in VAS ratings of pain (P=0.005), OHIP-14 scores (P=0.036) and OHQOL-UK© scores (P=0.003) between the start and end of the trial. In conclusion, both OHQOL-UK© and OHIP-14, patient-centred outcome measures are sensitive to the clinical effects of topical betamethasone in the treatment of oral lichen planus.
Persistent Identifierhttp://hdl.handle.net/10722/66585
ISSN
2015 Impact Factor: 1.563
2015 SCImago Journal Rankings: 0.854
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMcGrath, Cen_HK
dc.contributor.authorHegarty, AMen_HK
dc.contributor.authorHodgson, TAen_HK
dc.contributor.authorPorter, SRen_HK
dc.date.accessioned2010-09-06T05:47:36Z-
dc.date.available2010-09-06T05:47:36Z-
dc.date.issued2003en_HK
dc.identifier.citationInternational Journal Of Oral And Maxillofacial Surgery, 2003, v. 32 n. 3, p. 334-336en_HK
dc.identifier.issn0901-5027en_HK
dc.identifier.urihttp://hdl.handle.net/10722/66585-
dc.description.abstractThe aim of this study was to evaluate the sensitivity of two patient-centred outcome measures to the topical application of a corticosteroid (betamethasone) in the treatment of oral lichen planus (OLP). Forty-eight patients with clinical and histological features of OLP were recruited to take part in a 6-week study of the effectiveness of topical betamethasone for the treatment of symptomatic OLP. Participants completed a questionnaire incorporating the 16-item UK Oral Health Related Quality Of Life measure (OHQOL- UK©) and the 14-item Oral Health Impact Profile (OHIP-14), rated their pain on 'global' and visual analogue scales (VAS) and underwent an oral examination, at the start and end of the trial. Four (8%) patients failed to complete the study. The clinical signs of OLP had improved for half (22) of the patients following treatment. Twenty-nine (66%) reported that their oral pain had reduced ('global' scale). More objectively, there were significant differences in VAS ratings of pain (P=0.005), OHIP-14 scores (P=0.036) and OHQOL-UK© scores (P=0.003) between the start and end of the trial. In conclusion, both OHQOL-UK© and OHIP-14, patient-centred outcome measures are sensitive to the clinical effects of topical betamethasone in the treatment of oral lichen planus.en_HK
dc.languageengen_HK
dc.publisherChurchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/ijomen_HK
dc.relation.ispartofInternational Journal of Oral and Maxillofacial Surgeryen_HK
dc.subject.meshBetamethasone - analogs & derivatives - therapeutic useen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGlucocorticoids - therapeutic useen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLichen Planus, Oral - drug therapyen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshOutcome Assessment (Health Care) - methodsen_HK
dc.subject.meshPain Measurementen_HK
dc.subject.meshQuality of Lifeen_HK
dc.subject.meshQuestionnairesen_HK
dc.subject.meshReproducibility of Resultsen_HK
dc.subject.meshSickness Impact Profileen_HK
dc.titlePatient-centred outcome measures for oral mucosal disease are sensitive to treatmenten_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0901-5027&volume=32&spage=334&epage=336&date=2003&atitle=Patient-centred+outcome+measures+for+oral+mucosal+disease+are+sensitive+to+treatmenten_HK
dc.identifier.emailMcGrath, C:mcgrathc@hkucc.hku.hken_HK
dc.identifier.authorityMcGrath, C=rp00037en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1054/ijom.2002.0377en_HK
dc.identifier.pmid12767883-
dc.identifier.scopuseid_2-s2.0-0037864213en_HK
dc.identifier.hkuros81442en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0037864213&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume32en_HK
dc.identifier.issue3en_HK
dc.identifier.spage334en_HK
dc.identifier.epage336en_HK
dc.identifier.isiWOS:000183513900016-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridMcGrath, C=7102335507en_HK
dc.identifier.scopusauthoridHegarty, AM=7007165343en_HK
dc.identifier.scopusauthoridHodgson, TA=7102167887en_HK
dc.identifier.scopusauthoridPorter, SR=7201730425en_HK

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