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Article: A study of the comparative efficacy of three common analgesics in the control of pain after third molar surgery under local anaesthesia

TitleA study of the comparative efficacy of three common analgesics in the control of pain after third molar surgery under local anaesthesia
Authors
Issue Date2002
PublisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0045-0421
Citation
Australian Dental Journal, 2002, v. 47 n. 4, p. 327-330 How to Cite?
AbstractBackground: The aim of this study was to evaluate the comparative efficacy of three commonly used analgesics (Panadeine, Diflunisal and Etodolac) in the control of pain after third molar surgery under local anaesthesia. Methods: A randomized control study. Outcome of primary efficacy was judged by overall assessment of the area under the curve of graphs for pain intensity, measured from serial visual analogue scales over a 24-hour period. Other measures of efficacy included the number (per cent) of patients who took 'additional' analgesics and the incidence of adverse effects occurring in each treatment group over the study period. Results: The three drugs were effective in the control of post-operative pain (p<0.01). Variations in pain intensity and the use of additional medication between the treatment groups were observed over the study period. The Diflunisal group experienced less pain than the Panadeine or Etodolac group (p<0.01). Furthermore, a lesser number of those in the Diflunisal group used additional medication compared to the other two groups (p<0.01). The incidence of side effects from all three drugs was low. Conclusion: Diflunisal is superior in the control of pain following third molar surgery under local anaesthesia than either Panadeine or Etodolac, and has few side effects.
Persistent Identifierhttp://hdl.handle.net/10722/66564
ISSN
2015 Impact Factor: 1.272
2015 SCImago Journal Rankings: 0.482
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorComfort, MBen_HK
dc.contributor.authorTse, ASKen_HK
dc.contributor.authorTsang, ACCen_HK
dc.contributor.authorMcGrath, Cen_HK
dc.date.accessioned2010-09-06T05:47:25Z-
dc.date.available2010-09-06T05:47:25Z-
dc.date.issued2002en_HK
dc.identifier.citationAustralian Dental Journal, 2002, v. 47 n. 4, p. 327-330en_HK
dc.identifier.issn0045-0421en_HK
dc.identifier.urihttp://hdl.handle.net/10722/66564-
dc.description.abstractBackground: The aim of this study was to evaluate the comparative efficacy of three commonly used analgesics (Panadeine, Diflunisal and Etodolac) in the control of pain after third molar surgery under local anaesthesia. Methods: A randomized control study. Outcome of primary efficacy was judged by overall assessment of the area under the curve of graphs for pain intensity, measured from serial visual analogue scales over a 24-hour period. Other measures of efficacy included the number (per cent) of patients who took 'additional' analgesics and the incidence of adverse effects occurring in each treatment group over the study period. Results: The three drugs were effective in the control of post-operative pain (p<0.01). Variations in pain intensity and the use of additional medication between the treatment groups were observed over the study period. The Diflunisal group experienced less pain than the Panadeine or Etodolac group (p<0.01). Furthermore, a lesser number of those in the Diflunisal group used additional medication compared to the other two groups (p<0.01). The incidence of side effects from all three drugs was low. Conclusion: Diflunisal is superior in the control of pain following third molar surgery under local anaesthesia than either Panadeine or Etodolac, and has few side effects.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0045-0421en_HK
dc.relation.ispartofAustralian Dental Journalen_HK
dc.subject.meshAcetaminophen - adverse effects - therapeutic useen_HK
dc.subject.meshAnalgesics - adverse effects - therapeutic useen_HK
dc.subject.meshAnalgesics, Non-Narcotic - adverse effects - therapeutic useen_HK
dc.subject.meshAnalgesics, Opioid - adverse effects - therapeutic useen_HK
dc.subject.meshAnesthesia, Dentalen_HK
dc.subject.meshAnesthesia, Localen_HK
dc.subject.meshAnti-Inflammatory Agents, Non-Steroidal - adverse effects - therapeutic useen_HK
dc.subject.meshArea Under Curveen_HK
dc.subject.meshChi-Square Distributionen_HK
dc.subject.meshCodeine - adverse effects - therapeutic useen_HK
dc.subject.meshCyclooxygenase Inhibitors - adverse effects - therapeutic useen_HK
dc.subject.meshDiflunisal - adverse effects - therapeutic useen_HK
dc.subject.meshDrug Combinationsen_HK
dc.subject.meshEtodolac - adverse effects - therapeutic useen_HK
dc.subject.meshFollow-Up Studiesen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMolar, Third - surgeryen_HK
dc.subject.meshPain Measurementen_HK
dc.subject.meshPain, Postoperative - prevention & controlen_HK
dc.subject.meshStatistics, Nonparametricen_HK
dc.subject.meshTooth Extractionen_HK
dc.subject.meshTooth, Impacted - surgeryen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.titleA study of the comparative efficacy of three common analgesics in the control of pain after third molar surgery under local anaesthesiaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0045-0421&volume=47&issue=4&spage=327&epage=330&date=2002&atitle=A+study+of+the+comparative+efficacy+of+three+common+analgesics+in+the+control+of+pain+after+third+molar+surgery+under+local+anaesthesiaen_HK
dc.identifier.emailMcGrath, C:mcgrathc@hkucc.hku.hken_HK
dc.identifier.authorityMcGrath, C=rp00037en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid12587769en_HK
dc.identifier.scopuseid_2-s2.0-0037984427en_HK
dc.identifier.hkuros80476en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0037984427&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume47en_HK
dc.identifier.issue4en_HK
dc.identifier.spage327en_HK
dc.identifier.epage330en_HK
dc.identifier.isiWOS:000180098100009-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridComfort, MB=7003605684en_HK
dc.identifier.scopusauthoridTse, ASK=36870535600en_HK
dc.identifier.scopusauthoridTsang, ACC=36949359700en_HK
dc.identifier.scopusauthoridMcGrath, C=7102335507en_HK

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