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Article: Pierre Robin sequence: appearances and 25 years of experience with an innovative treatment protocol

TitlePierre Robin sequence: appearances and 25 years of experience with an innovative treatment protocol
Authors
KeywordsCleft palate
Fairbairn-Robin
Glossoptosis
Micrognathia
Palate reconstruction
Pierre Robin
Plate therapy
Issue Date2009
PublisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/jpedsurg
Citation
Journal Of Pediatric Surgery, 2009, v. 44 n. 11, p. 2112-2118 How to Cite?
AbstractPurpose: The aim of the study was to evaluate the largest number of Pierre Robin sequence (PRS) cases to date and its treatment outcome. Design: This is a retrospective study. Settings: The study was conducted in a tertiary care university hospital. Patients: One hundred eighty-eight patients with PRS have been subjected to analysis, defined by the clinical triad of glossoptosis, retro/micrognathia, and cleft or agenesis of the palate, for incidence, risk factors, associated syndromes, other concomitant abnormalities, airway and feeding difficulties, and outcome regarding the neonatal and perinatal surgical and nonsurgical management. Results: The incidence of PRS was 6.02%. Risk factors were found in 41.5% of mothers with children with PRS. Eleven other syndromes/appearances were associated. Feeding difficulties were seen in 51.8% of the patients. Glossopexy (6.9%) and tracheotomy (2.13%) for airway management were performed very seldom. The suction and drinking plate as well as the surgical treatment protocol may be considered to be the reasons for reduced airway (up to 91.0%), feeding problems (up to 79.9%), and mortality rate (2.1%). Conclusion: The Pierre Robin sequence, as seen as a heterogeneous group, presents with variation of the cleft palate defects with glossoptosis and concomitant micrognathic mandible. The surgical management and certain prepalatal intervention as nonsurgical management with an innovative treatment strategy were evaluated. © 2009 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/66391
ISSN
2015 Impact Factor: 1.733
2015 SCImago Journal Rankings: 0.802
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorBütow, KWen_HK
dc.contributor.authorHoogendijk, CFen_HK
dc.contributor.authorZwahlen, RAen_HK
dc.date.accessioned2010-09-06T05:45:58Z-
dc.date.available2010-09-06T05:45:58Z-
dc.date.issued2009en_HK
dc.identifier.citationJournal Of Pediatric Surgery, 2009, v. 44 n. 11, p. 2112-2118en_HK
dc.identifier.issn0022-3468en_HK
dc.identifier.urihttp://hdl.handle.net/10722/66391-
dc.description.abstractPurpose: The aim of the study was to evaluate the largest number of Pierre Robin sequence (PRS) cases to date and its treatment outcome. Design: This is a retrospective study. Settings: The study was conducted in a tertiary care university hospital. Patients: One hundred eighty-eight patients with PRS have been subjected to analysis, defined by the clinical triad of glossoptosis, retro/micrognathia, and cleft or agenesis of the palate, for incidence, risk factors, associated syndromes, other concomitant abnormalities, airway and feeding difficulties, and outcome regarding the neonatal and perinatal surgical and nonsurgical management. Results: The incidence of PRS was 6.02%. Risk factors were found in 41.5% of mothers with children with PRS. Eleven other syndromes/appearances were associated. Feeding difficulties were seen in 51.8% of the patients. Glossopexy (6.9%) and tracheotomy (2.13%) for airway management were performed very seldom. The suction and drinking plate as well as the surgical treatment protocol may be considered to be the reasons for reduced airway (up to 91.0%), feeding problems (up to 79.9%), and mortality rate (2.1%). Conclusion: The Pierre Robin sequence, as seen as a heterogeneous group, presents with variation of the cleft palate defects with glossoptosis and concomitant micrognathic mandible. The surgical management and certain prepalatal intervention as nonsurgical management with an innovative treatment strategy were evaluated. © 2009 Elsevier Inc. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/jpedsurgen_HK
dc.relation.ispartofJournal of Pediatric Surgeryen_HK
dc.subjectCleft palateen_HK
dc.subjectFairbairn-Robinen_HK
dc.subjectGlossoptosisen_HK
dc.subjectMicrognathiaen_HK
dc.subjectPalate reconstructionen_HK
dc.subjectPierre Robinen_HK
dc.subjectPlate therapyen_HK
dc.subject.meshAirway Obstruction - etiology - surgery-
dc.subject.meshCleft Palate - mortality - surgery-
dc.subject.meshEating Disorders - surgery-
dc.subject.meshPierre Robin Syndrome - diagnosis - surgery - therapy-
dc.subject.meshTongue/abnormalities/surgery-
dc.titlePierre Robin sequence: appearances and 25 years of experience with an innovative treatment protocolen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-3468&volume=44 &issue=11&spage=2112&epage=2118&date=2009&atitle=Pierre+Robin+sequence:+appearances+and+25+years+of+experience+with+an+innovative+treatment+protocolen_HK
dc.identifier.emailZwahlen, RA:zwahlen@hku.hken_HK
dc.identifier.authorityZwahlen, RA=rp00055en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jpedsurg.2009.04.018en_HK
dc.identifier.pmid19944218-
dc.identifier.scopuseid_2-s2.0-70450080399en_HK
dc.identifier.hkuros169288en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-70450080399&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume44en_HK
dc.identifier.issue11en_HK
dc.identifier.spage2112en_HK
dc.identifier.epage2118en_HK
dc.identifier.eissn1531-5037-
dc.identifier.isiWOS:000274393600010-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridBütow, KW=7003648201en_HK
dc.identifier.scopusauthoridHoogendijk, CF=12040925100en_HK
dc.identifier.scopusauthoridZwahlen, RA=7004217269en_HK

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