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Article: Inhibitory effect of quercetin on periodontal pathogens in vitro

TitleInhibitory effect of quercetin on periodontal pathogens in vitro
Authors
KeywordsActinobacillus actinomycetemcomitans (Aa)
Periodontal pathogens
Porphyromonas gingivalis (Pg)
Quertin
Issue Date2010
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/12567
Citation
Phytotherapy Research, 2010, v. 24 n. 6, p. 817-820 How to Cite?
AbstractActinobacillus actinomycetemcomitans (Aa) and Porphyromonas gingivalis (Pg) are bacteria strongly associated with early onset, progressive and refractory periodontal disease and associated alveolar bone loss. Quercetin is a flavonoid found in many foods including apples, onions and tea. The aim of this study was to evaluate the effect of quercetin on in vitro growth of periodontal pathogens Aa and Pg. For comparison, quercetin's effect on several oral microbes was also evaluated. Different concentrations of quercetin solution were added to calibrated suspensions of Aa and Pg. All suspensions were incubated for 1, 3, 6, and 24 h in an anaerobic chamber at 37° C. At each time point, selected dilutions from each culture broth were plated on blood agar plates. Colonies appearing on blood agar plates were visually counted on 3 days for Aa and 5 days for Pg. Minimum inhibitory concentrations of both periodontal pathogens were also determined. Both periodontal bacteria showed a significant decrease (p < 0.05) in viable counts after 1 h. No colony forming units of Pg could be observed after 24 h. The results suggest that quercetin possesses significant antimicrobial properties on periodontal pathogens in vitro. Copyright © 2009 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/66357
ISSN
2015 Impact Factor: 2.694
2015 SCImago Journal Rankings: 0.842
ISI Accession Number ID
Funding AgencyGrant Number
University of Hong Kong Committee10208640.36170.08000.310.01
Funding Information:

This study was supported by the University of Hong Kong Committee on Research and Conference Grant No. 10208640.36170.08000.310.01

References

 

DC FieldValueLanguage
dc.contributor.authorGeoghegan, Fen_HK
dc.contributor.authorWong, RWKen_HK
dc.contributor.authorRabie, ABMen_HK
dc.date.accessioned2010-09-06T05:45:41Z-
dc.date.available2010-09-06T05:45:41Z-
dc.date.issued2010en_HK
dc.identifier.citationPhytotherapy Research, 2010, v. 24 n. 6, p. 817-820en_HK
dc.identifier.issn0951-418Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/66357-
dc.description.abstractActinobacillus actinomycetemcomitans (Aa) and Porphyromonas gingivalis (Pg) are bacteria strongly associated with early onset, progressive and refractory periodontal disease and associated alveolar bone loss. Quercetin is a flavonoid found in many foods including apples, onions and tea. The aim of this study was to evaluate the effect of quercetin on in vitro growth of periodontal pathogens Aa and Pg. For comparison, quercetin's effect on several oral microbes was also evaluated. Different concentrations of quercetin solution were added to calibrated suspensions of Aa and Pg. All suspensions were incubated for 1, 3, 6, and 24 h in an anaerobic chamber at 37° C. At each time point, selected dilutions from each culture broth were plated on blood agar plates. Colonies appearing on blood agar plates were visually counted on 3 days for Aa and 5 days for Pg. Minimum inhibitory concentrations of both periodontal pathogens were also determined. Both periodontal bacteria showed a significant decrease (p < 0.05) in viable counts after 1 h. No colony forming units of Pg could be observed after 24 h. The results suggest that quercetin possesses significant antimicrobial properties on periodontal pathogens in vitro. Copyright © 2009 John Wiley & Sons, Ltd.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/12567en_HK
dc.relation.ispartofPhytotherapy Researchen_HK
dc.rightsPhytotherapy Research. Copyright © John Wiley & Sons Ltd.en_HK
dc.subjectActinobacillus actinomycetemcomitans (Aa)en_HK
dc.subjectPeriodontal pathogensen_HK
dc.subjectPorphyromonas gingivalis (Pg)en_HK
dc.subjectQuertinen_HK
dc.subject.meshActinobacillus actinomycetemcomitans - drug effects - growth & developmenten_HK
dc.subject.meshCandida - drug effects - growth & developmenten_HK
dc.subject.meshColony Count, Microbialen_HK
dc.subject.meshMicrobial Sensitivity Testsen_HK
dc.subject.meshPeriodontal Diseases - microbiologyen_HK
dc.subject.meshPorphyromonas gingivalis - drug effects - growth & developmenten_HK
dc.subject.meshQuercetin - pharmacologyen_HK
dc.titleInhibitory effect of quercetin on periodontal pathogens in vitroen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0951-418X&volume=&spage=&epage=&date=2009&atitle=Inhibitory+Effect+of+Quercetin+on+Periodontal+Pathogens+in+vitroen_HK
dc.identifier.emailWong, RWK: fyoung@hku.hken_HK
dc.identifier.emailRabie, ABM: rabie@hku.hken_HK
dc.identifier.authorityWong, RWK=rp00038en_HK
dc.identifier.authorityRabie, ABM=rp00029en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/ptr.3014en_HK
dc.identifier.pmid19957242-
dc.identifier.scopuseid_2-s2.0-77953273395en_HK
dc.identifier.hkuros168354en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77953273395&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume24en_HK
dc.identifier.issue6en_HK
dc.identifier.spage817en_HK
dc.identifier.epage820en_HK
dc.identifier.eissn1099-1573-
dc.identifier.isiWOS:000279070200004-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridGeoghegan, F=36672849000en_HK
dc.identifier.scopusauthoridWong, RWK=7402127170en_HK
dc.identifier.scopusauthoridRabie, ABM=7007172734en_HK

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