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Article: Variations in crevicular fluid elastase levels in periodontitis patients on long-term maintenance.

TitleVariations in crevicular fluid elastase levels in periodontitis patients on long-term maintenance.
Authors
Issue Date1995
PublisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/EOS
Citation
European Journal Of Oral Sciences, 1995, v. 103 n. 2, p. Pt 1 How to Cite?
AbstractGranulocyte elastase was determined in the gingival crevicular fluid (GCF) of 18 periodontitis patients. They initially had similar severity of disease but had responded differently to 5-yr maintenance, 13 responders and 5 non-responders. A total of 102 sites were investigated and categorized as: i) consistently healthy, ii) healthy after treatment, iii) gingivitis, and iv) periodontitis, according to clinical criteria. GCF elastase activity was determined with a granulocyte-specific substrate. The sites from non-responders had consistently higher elastase levels than the corresponding category of sites from responders, despite similar gingival inflammation and periodontal destruction, with the exception of consistently healthy sites. Within the non-responders, the periodontitis sites had higher elastase levels than the gingivitis sites commensurate with probing depth, while no difference existed between gingivitis sites and sites healthy after treatment, despite a difference in probing depth. In contrast, in the responders similar elastase levels were found at the periodontitis sites and gingivitis sites despite difference in probing depth, while both diseased sites had higher elastase levels than the sites healthy after treatment, commensurate with probing depth. This study suggests that increased granulocyte-specific elastase levels in GCF may serve as a diagnostic marker for refractory periodontitis patients.
Persistent Identifierhttp://hdl.handle.net/10722/66278
ISSN
2015 Impact Factor: 1.607
2015 SCImago Journal Rankings: 0.681
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorJin, LJen_HK
dc.contributor.authorSöder, POen_HK
dc.contributor.authorAsman, Ben_HK
dc.contributor.authorSöder, Ben_HK
dc.contributor.authorPuriene, Aen_HK
dc.contributor.authorBergström, Ken_HK
dc.date.accessioned2010-09-06T05:45:02Z-
dc.date.available2010-09-06T05:45:02Z-
dc.date.issued1995en_HK
dc.identifier.citationEuropean Journal Of Oral Sciences, 1995, v. 103 n. 2, p. Pt 1en_HK
dc.identifier.issn0909-8836en_HK
dc.identifier.urihttp://hdl.handle.net/10722/66278-
dc.description.abstractGranulocyte elastase was determined in the gingival crevicular fluid (GCF) of 18 periodontitis patients. They initially had similar severity of disease but had responded differently to 5-yr maintenance, 13 responders and 5 non-responders. A total of 102 sites were investigated and categorized as: i) consistently healthy, ii) healthy after treatment, iii) gingivitis, and iv) periodontitis, according to clinical criteria. GCF elastase activity was determined with a granulocyte-specific substrate. The sites from non-responders had consistently higher elastase levels than the corresponding category of sites from responders, despite similar gingival inflammation and periodontal destruction, with the exception of consistently healthy sites. Within the non-responders, the periodontitis sites had higher elastase levels than the gingivitis sites commensurate with probing depth, while no difference existed between gingivitis sites and sites healthy after treatment, despite a difference in probing depth. In contrast, in the responders similar elastase levels were found at the periodontitis sites and gingivitis sites despite difference in probing depth, while both diseased sites had higher elastase levels than the sites healthy after treatment, commensurate with probing depth. This study suggests that increased granulocyte-specific elastase levels in GCF may serve as a diagnostic marker for refractory periodontitis patients.en_HK
dc.languageengen_HK
dc.publisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/EOSen_HK
dc.relation.ispartofEuropean journal of oral sciencesen_HK
dc.rightsThe definitive version is available at www.blackwell-synergy.com-
dc.subject.meshGingival Crevicular Fluid - enzymology-
dc.subject.meshGingivitis - enzymology - therapy-
dc.subject.meshGranulocytes - enzymology-
dc.subject.meshPancreatic Elastase - analysis-
dc.subject.meshPeriodontitis - enzymology - therapy-
dc.titleVariations in crevicular fluid elastase levels in periodontitis patients on long-term maintenance.en_HK
dc.typeArticleen_HK
dc.identifier.emailJin, LJ:ljjin@hkucc.hku.hken_HK
dc.identifier.authorityJin, LJ=rp00028en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1600-0722.1995.tb00121.x-
dc.identifier.pmid7767710-
dc.identifier.scopuseid_2-s2.0-0029282279en_HK
dc.identifier.hkuros3462en_HK
dc.identifier.hkuros13869-
dc.identifier.volume103en_HK
dc.identifier.issue2en_HK
dc.identifier.spagePt 1en_HK
dc.identifier.epagePt 1en_HK
dc.identifier.isiWOS:A1995QQ98100004-
dc.publisher.placeDenmarken_HK
dc.identifier.scopusauthoridJin, LJ=7403328850en_HK
dc.identifier.scopusauthoridSöder, PO=7006570984en_HK
dc.identifier.scopusauthoridAsman, B=7005314377en_HK
dc.identifier.scopusauthoridSöder, B=6701795462en_HK
dc.identifier.scopusauthoridPuriene, A=55174980000en_HK
dc.identifier.scopusauthoridBergström, K=7102766602en_HK

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