Article: Supra-gingival microbiota in Sjögren's syndrome

File Download Links for fulltext
(May Require Subscription)
Supplementary
  • Basic View
  • Metadata View
  • XML View
TitleSupra-gingival microbiota in Sjögren's syndrome
AuthorsLeung, KCM1
Leung, WK1
McMillan, AS1
KeywordsDental plaque
Microorganism
Saliva
Sjögren's syndrome
Xerostomia
Issue Date2007
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00784/index.htm
CitationClinical Oral Investigations, 2007, v. 11 n. 4, p. 415-423 [How to Cite?]
DOI: http://dx.doi.org/10.1007/s00784-007-0132-1
AbstractThe aim of this study was to investigate the microbiota of noncaries associated supra-gingival plaque (SGP) microbiology in Sjögren's syndrome (SS). Stimulated whole saliva (SWS) and full-mouth SGP on intact tooth surfaces were collected from 26 primary (p) SS, 27 secondary (s) SS, and 29 control subjects for selective culture of lactobacilli, mutans streptococci, and aerobic and facultatively anaerobic gram-negative rods (AGNR). Predominant cultivable anaerobes from SGP of 11 randomly selected subjects from each group were investigated. Clinical and sialometric data were also collected. SS sufferers had significantly lower SWS flow rate and higher mean DMFT (decayed, missing, filled teeth), while pSS subjects also had lower SWS pH and fewer standing teeth. Lactobacillus acidophilus levels in SWS (P=0.012) and SGP (P <0.0001) were significantly elevated in pSS sufferers compared with sSS individuals and controls. AGNR isolation was uncommon. SS sufferers had significantly lower proportion of gram-negative species (P=0.047). Non-oral species were isolated in greater proportions from pSS SGP (P=0.007). Subjects with pSS harbored increased levels of L. acidophilus and non-oral species, while SS sufferers generally had lower proportions of gram-negative species. The microbial composition of noncaries associated SGP indicates a potential source of increased caries risk in SS. © Springer-Verlag 2007.
ISSN1432-6981
2011 Impact Factor: 2.364
2011 SCImago Journal Rankings: 0.096
DOIhttp://dx.doi.org/10.1007/s00784-007-0132-1
ISI Accession Number IDWOS:000251009800014
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorLeung, KCM
dc.contributor.authorLeung, WK
dc.contributor.authorMcMillan, AS
dc.date.accessioned2010-09-06T05:45:02Z
dc.date.available2010-09-06T05:45:02Z
dc.date.issued2007
dc.description.abstractThe aim of this study was to investigate the microbiota of noncaries associated supra-gingival plaque (SGP) microbiology in Sjögren's syndrome (SS). Stimulated whole saliva (SWS) and full-mouth SGP on intact tooth surfaces were collected from 26 primary (p) SS, 27 secondary (s) SS, and 29 control subjects for selective culture of lactobacilli, mutans streptococci, and aerobic and facultatively anaerobic gram-negative rods (AGNR). Predominant cultivable anaerobes from SGP of 11 randomly selected subjects from each group were investigated. Clinical and sialometric data were also collected. SS sufferers had significantly lower SWS flow rate and higher mean DMFT (decayed, missing, filled teeth), while pSS subjects also had lower SWS pH and fewer standing teeth. Lactobacillus acidophilus levels in SWS (P=0.012) and SGP (P <0.0001) were significantly elevated in pSS sufferers compared with sSS individuals and controls. AGNR isolation was uncommon. SS sufferers had significantly lower proportion of gram-negative species (P=0.047). Non-oral species were isolated in greater proportions from pSS SGP (P=0.007). Subjects with pSS harbored increased levels of L. acidophilus and non-oral species, while SS sufferers generally had lower proportions of gram-negative species. The microbial composition of noncaries associated SGP indicates a potential source of increased caries risk in SS. © Springer-Verlag 2007.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationClinical Oral Investigations, 2007, v. 11 n. 4, p. 415-423 [How to Cite?]
DOI: http://dx.doi.org/10.1007/s00784-007-0132-1
dc.identifier.doihttp://dx.doi.org/10.1007/s00784-007-0132-1
dc.identifier.epage423
dc.identifier.hkuros138970
dc.identifier.isiWOS:000251009800014
dc.identifier.issn1432-6981
2011 Impact Factor: 2.364
2011 SCImago Journal Rankings: 0.096
dc.identifier.issue4
dc.identifier.pmid17609998
dc.identifier.scopuseid_2-s2.0-36348994220
dc.identifier.spage415
dc.identifier.urihttp://hdl.handle.net/10722/66277
dc.identifier.volume11
dc.languageeng
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00784/index.htm
dc.publisher.placeGermany
dc.relation.ispartofClinical Oral Investigations
dc.relation.referencesReferences in Scopus
dc.rightsThe original publication is available at www.springerlink.com
dc.subject.meshDental Plaque - microbiology
dc.subject.meshGram-Negative Anaerobic Bacteria - isolation and purification
dc.subject.meshLactobacillus - classification - isolation and purification
dc.subject.meshLactobacillus acidophilus - isolation and purification
dc.subject.meshSjogren's Syndrome - microbiology - physiopathology
dc.subjectDental plaque
dc.subjectMicroorganism
dc.subjectSaliva
dc.subjectSjögren's syndrome
dc.subjectXerostomia
dc.titleSupra-gingival microbiota in Sjögren's syndrome
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong