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Article: The effect of casein phosphopeptide-amorphous calcium phosphate on remineralization of artificial caries-like lesions: An in vitro study

TitleThe effect of casein phosphopeptide-amorphous calcium phosphate on remineralization of artificial caries-like lesions: An in vitro study
Authors
KeywordsCaries
CPP-ACP
Demineralization
PH-cycling
Remineralization
Issue Date2008
PublisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0045-0421
Citation
Australian Dental Journal, 2008, v. 53 n. 1, p. 34-40 How to Cite?
AbstractBackground: The aims of this study were to investigate the efficacy of CPP-ACP containing Tooth Mousse on the remineralization of enamel lesions and to compare its efficacy to that of a fluoride-containing toothpaste. Methods: Permanent teeth were placed in demineralizing solution for 96 hours to produce artificial caries-like lesions 120-200 m in depth. They were sectioned into 100-150 m thick samples and randomly assigned to five groups: for Group A, a fluoridated toothpaste (1100 ppm) was used as a positive control and in Group B, a non-fluoridated toothpaste was used as a negative control. Tooth Mousse containing CPP-ACP was tested by three different means: as a toothpaste (Group C); as a topical coating (Group D); and (Group E) as a topical coating after treating the sections with the same fluoridated toothpaste as in Group A. Results: The lesion depth decreased significantly by 7 per cent in Group A, 10.1 per cent in Groups C and D, and 13.1 per cent in Group E (Paired t- test, p < 0.05), while in Group B the lesion depth increased significantly by 23 per cent. Conclusions: Based on the data obtained, CPP-ACP containing Tooth Mousse remineralized initial enamel lesions and it showed a higher remineralizing potential when applied as a topical coating after the use of a fluoridated toothpaste. © 2008 Australian Dental Association.
Persistent Identifierhttp://hdl.handle.net/10722/66246
ISSN
2015 Impact Factor: 1.272
2015 SCImago Journal Rankings: 0.482
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorKumar, VLNen_HK
dc.contributor.authorItthagarun, Aen_HK
dc.contributor.authorKing, NMen_HK
dc.date.accessioned2010-09-06T05:44:46Z-
dc.date.available2010-09-06T05:44:46Z-
dc.date.issued2008en_HK
dc.identifier.citationAustralian Dental Journal, 2008, v. 53 n. 1, p. 34-40en_HK
dc.identifier.issn0045-0421en_HK
dc.identifier.urihttp://hdl.handle.net/10722/66246-
dc.description.abstractBackground: The aims of this study were to investigate the efficacy of CPP-ACP containing Tooth Mousse on the remineralization of enamel lesions and to compare its efficacy to that of a fluoride-containing toothpaste. Methods: Permanent teeth were placed in demineralizing solution for 96 hours to produce artificial caries-like lesions 120-200 m in depth. They were sectioned into 100-150 m thick samples and randomly assigned to five groups: for Group A, a fluoridated toothpaste (1100 ppm) was used as a positive control and in Group B, a non-fluoridated toothpaste was used as a negative control. Tooth Mousse containing CPP-ACP was tested by three different means: as a toothpaste (Group C); as a topical coating (Group D); and (Group E) as a topical coating after treating the sections with the same fluoridated toothpaste as in Group A. Results: The lesion depth decreased significantly by 7 per cent in Group A, 10.1 per cent in Groups C and D, and 13.1 per cent in Group E (Paired t- test, p < 0.05), while in Group B the lesion depth increased significantly by 23 per cent. Conclusions: Based on the data obtained, CPP-ACP containing Tooth Mousse remineralized initial enamel lesions and it showed a higher remineralizing potential when applied as a topical coating after the use of a fluoridated toothpaste. © 2008 Australian Dental Association.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0045-0421en_HK
dc.relation.ispartofAustralian Dental Journalen_HK
dc.subjectCariesen_HK
dc.subjectCPP-ACPen_HK
dc.subjectDemineralizationen_HK
dc.subjectPH-cyclingen_HK
dc.subjectRemineralizationen_HK
dc.titleThe effect of casein phosphopeptide-amorphous calcium phosphate on remineralization of artificial caries-like lesions: An in vitro studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0045-0421&volume=53&spage=34&epage=40&date=2008&atitle=The+effect+of+casein+phosphopeptide-amorphous+calcium+phosphate+on+remineralization+of+artificial+caries-like+lesions:+an+in+vitro+studyen_HK
dc.identifier.emailKing, NM: hhdbknm@hkucc.hku.hken_HK
dc.identifier.authorityKing, NM=rp00006en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1834-7819.2007.00006.xen_HK
dc.identifier.pmid18304239-
dc.identifier.scopuseid_2-s2.0-41849147919en_HK
dc.identifier.hkuros141245en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-41849147919&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume53en_HK
dc.identifier.issue1en_HK
dc.identifier.spage34en_HK
dc.identifier.epage40en_HK
dc.identifier.isiWOS:000254096200006-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridKumar, VLN=55267764200en_HK
dc.identifier.scopusauthoridItthagarun, A=6701591745en_HK
dc.identifier.scopusauthoridKing, NM=7201762850en_HK

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