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Article: Reduction in antimicrobial substantivity of MTAD following after initial sodium hypochlorite irrigation

TitleReduction in antimicrobial substantivity of MTAD following after initial sodium hypochlorite irrigation
Authors
Issue Date2006
PublisherElsevier Inc. The Journal's web site is located at http://www.jendodon.com
Citation
Journal of endodontics, 2006, v. 32 n. 10, p. 970-975 How to Cite?
AbstractPotential intrinsic tetracycline staining of intraradicular dentin has been observed when BioPure MTAD was employed as the final irrigant after initial rinsing with NaOCl. This study examined the effect of NaOCl-MTAD interaction on the antimicrobial substantivity of MTAD in dentin. Dentin cores previously irrigated with either MTAD, or in conjunction with 1.3% NaOCl as an initial irrigant were placed on blood agar plates inoculated with Escherichia faecalis at 105 cfu/ml. Dentin cores irrigated with 1.3% NaOCl only, and autoclaved dentin disks were used as the respective positive and negative controls. After anaerobic incubation, the mean diameter of bacterial inhibition zones formed around the MTAD group was significantly larger than the NaOCl/MTAD group, which, in turn, was not significantly different from the NaOCl positive control. Oxidation of MTAD by NaOCl resulted in the partial loss of antimicrobial substantivity in a manner similar to the peroxidation of tetracycline by reactive oxygen species.
Persistent Identifierhttp://hdl.handle.net/10722/66093
ISSN
2015 Impact Factor: 2.904
2015 SCImago Journal Rankings: 1.681
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTay, FRen_HK
dc.contributor.authorHiraishi, Nen_HK
dc.contributor.authorSchister, GSen_HK
dc.contributor.authorPashley, DHen_HK
dc.contributor.authorLoushine, RJen_HK
dc.contributor.authorOunsi, HFen_HK
dc.contributor.authorGrandini, Sen_HK
dc.contributor.authorYau, JYen_HK
dc.contributor.authorMazzoni, Aen_HK
dc.contributor.authorDonnelly, Aen_HK
dc.contributor.authorKing, NMen_HK
dc.date.accessioned2010-09-06T05:43:31Z-
dc.date.available2010-09-06T05:43:31Z-
dc.date.issued2006en_HK
dc.identifier.citationJournal of endodontics, 2006, v. 32 n. 10, p. 970-975en_HK
dc.identifier.issn0099-2399en_HK
dc.identifier.urihttp://hdl.handle.net/10722/66093-
dc.description.abstractPotential intrinsic tetracycline staining of intraradicular dentin has been observed when BioPure MTAD was employed as the final irrigant after initial rinsing with NaOCl. This study examined the effect of NaOCl-MTAD interaction on the antimicrobial substantivity of MTAD in dentin. Dentin cores previously irrigated with either MTAD, or in conjunction with 1.3% NaOCl as an initial irrigant were placed on blood agar plates inoculated with Escherichia faecalis at 105 cfu/ml. Dentin cores irrigated with 1.3% NaOCl only, and autoclaved dentin disks were used as the respective positive and negative controls. After anaerobic incubation, the mean diameter of bacterial inhibition zones formed around the MTAD group was significantly larger than the NaOCl/MTAD group, which, in turn, was not significantly different from the NaOCl positive control. Oxidation of MTAD by NaOCl resulted in the partial loss of antimicrobial substantivity in a manner similar to the peroxidation of tetracycline by reactive oxygen species.-
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.jendodon.comen_HK
dc.relation.ispartofJournal of endodonticsen_HK
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in <Journal title>. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in PUBLICATION, [VOL#, ISSUE#, (DATE)] DOI#en_HK
dc.subject.meshAnti-Bacterial Agents/administration & dosage - pharmacology-
dc.subject.meshCitric Acid - pharmacology-
dc.subject.meshDoxycycline/administration & dosage - analogs & derivatives/pharmacology-
dc.subject.meshPolysorbates - pharmacology-
dc.subject.meshRoot Canal Irrigants/administration & dosage - pharmacology-
dc.titleReduction in antimicrobial substantivity of MTAD following after initial sodium hypochlorite irrigationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0099-2399&volume=32&issue=10&spage=970&epage=975&date=2006&atitle=Reduction+in+antimicrobial+substantivity+of+MTAD+following+initial+sodium+hypochlorite+irrigationen_HK
dc.identifier.emailTay, FR: franktay@HKUCC.hku.hken_HK
dc.identifier.emailHiraishi, N: noriko11@HKUCC.hku.hken_HK
dc.identifier.emailKing, NM: hhdbknm@hkucc.hku.hken_HK
dc.identifier.authorityKing, NM=rp00006en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.joen.2006.03.016-
dc.identifier.pmid16982276-
dc.identifier.scopuseid_2-s2.0-33748536451-
dc.identifier.hkuros161682en_HK
dc.identifier.volume32-
dc.identifier.issue10-
dc.identifier.spage970-
dc.identifier.epage975-
dc.identifier.isiWOS:000240966200013-
dc.publisher.placeUnited States-

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