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Article: Salivary lysozyme and related parameters of a predominantly Chinese, HIV-infected cohort in Hong Kong

TitleSalivary lysozyme and related parameters of a predominantly Chinese, HIV-infected cohort in Hong Kong
Authors
Issue Date1999
PublisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1
Citation
Oral Diseases, 1999, v. 5 n. 3, p. 241-246 How to Cite?
AbstractOBJECTIVES: To evaluate the salivary lysozyme concentration, flow rate and pH of a predominantly Chinese, HIV-infected group in Hong Kong, and to compare with an equal number of age and gender-matched HIV-free individuals. STUDY DESIGN: A prospective longitudinal study over a 12-month period of 32 predominantly Chinese, male, HIV-infected group in a hospital setting in Hong Kong. Whole saliva collection by expectoration, lysozyme evaluation by 'lysoplate method'; pH and flow rate evaluation using standard methods and correlation with other clinical parameters using regression analysis. RESULTS: The flow rate and the pH of saliva were lower compared with HIV- free, healthy individuals (both P < 0.0001) and salivary lysozyme concentration of the HIV-infected group was 23% higher compared with the HIV- free group (P < 0.001), though there was no significant difference between the lysozyme output (P > 0.05) expressed as μg min-1. On multiple regression analysis, intravenous drug users had a higher salivary lysozyme concentration compared with the homosexual group (P = 0.0015) though other variables investigated were not significantly related to the salivary lysozyme concentrations. CONCLUSIONS: The significant changes in the flow rate, pH value and lysozyme concentration of whole saliva of the HIV-infected individuals as compared with the HIV-free, healthy individuals, may be due to the disease itself or a combination of factors including the medications used in the disease management.
Persistent Identifierhttp://hdl.handle.net/10722/66017
ISSN
2015 Impact Factor: 2.0
2015 SCImago Journal Rankings: 0.828
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTsang, CSPen_HK
dc.contributor.authorSamaranayake, LPen_HK
dc.date.accessioned2010-09-06T05:42:54Z-
dc.date.available2010-09-06T05:42:54Z-
dc.date.issued1999en_HK
dc.identifier.citationOral Diseases, 1999, v. 5 n. 3, p. 241-246en_HK
dc.identifier.issn1354-523Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/66017-
dc.description.abstractOBJECTIVES: To evaluate the salivary lysozyme concentration, flow rate and pH of a predominantly Chinese, HIV-infected group in Hong Kong, and to compare with an equal number of age and gender-matched HIV-free individuals. STUDY DESIGN: A prospective longitudinal study over a 12-month period of 32 predominantly Chinese, male, HIV-infected group in a hospital setting in Hong Kong. Whole saliva collection by expectoration, lysozyme evaluation by 'lysoplate method'; pH and flow rate evaluation using standard methods and correlation with other clinical parameters using regression analysis. RESULTS: The flow rate and the pH of saliva were lower compared with HIV- free, healthy individuals (both P < 0.0001) and salivary lysozyme concentration of the HIV-infected group was 23% higher compared with the HIV- free group (P < 0.001), though there was no significant difference between the lysozyme output (P > 0.05) expressed as μg min-1. On multiple regression analysis, intravenous drug users had a higher salivary lysozyme concentration compared with the homosexual group (P = 0.0015) though other variables investigated were not significantly related to the salivary lysozyme concentrations. CONCLUSIONS: The significant changes in the flow rate, pH value and lysozyme concentration of whole saliva of the HIV-infected individuals as compared with the HIV-free, healthy individuals, may be due to the disease itself or a combination of factors including the medications used in the disease management.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1en_HK
dc.relation.ispartofOral Diseasesen_HK
dc.subject.meshAdulten_HK
dc.subject.meshCandida albicans - isolation & purificationen_HK
dc.subject.meshCase-Control Studiesen_HK
dc.subject.meshHIV Infections - enzymologyen_HK
dc.subject.meshHong Kongen_HK
dc.subject.meshHumansen_HK
dc.subject.meshHydrogen-Ion Concentrationen_HK
dc.subject.meshLongitudinal Studiesen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshMuramidase - metabolismen_HK
dc.subject.meshRegression Analysisen_HK
dc.subject.meshSaliva - chemistry - enzymology - secretionen_HK
dc.subject.meshSecretory Rateen_HK
dc.titleSalivary lysozyme and related parameters of a predominantly Chinese, HIV-infected cohort in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1354-523X&volume=5&spage=241&epage=246&date=1999&atitle=Salivary+lysozyme+and+related+parameters+of+a+predominantly+Chinese,+HIV-infected+cohort+in+Hong+Kongen_HK
dc.identifier.emailTsang, CSP:csptsang@hkucc.hku.hken_HK
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_HK
dc.identifier.authorityTsang, CSP=rp00026en_HK
dc.identifier.authoritySamaranayake, LP=rp00023en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid10483071-
dc.identifier.scopuseid_2-s2.0-0032819261en_HK
dc.identifier.hkuros42697en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032819261&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume5en_HK
dc.identifier.issue3en_HK
dc.identifier.spage241en_HK
dc.identifier.epage246en_HK
dc.identifier.isiWOS:000083762400011-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTsang, CSP=7202936002en_HK
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_HK

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