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Article: The self-perceived symptom distress and health-related conditions associated with morning to evening diurnal cortisol patterns in outpatients with major depressive disorder

TitleThe self-perceived symptom distress and health-related conditions associated with morning to evening diurnal cortisol patterns in outpatients with major depressive disorder
Authors
KeywordsDepression levels
Major depressive disorder
Salivary cortisol
Sleep hours
Sleep quality
Suffering levels
Issue Date2010
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/psyneuen
Citation
Psychoneuroendocrinology, 2010, v. 35 n. 4, p. 503-515 How to Cite?
AbstractObjective: This study was an examination of 126 major depressive disorder (MDD) outpatients' morning to evening diurnal cortisol patterns to determine their association with family histories of mental illness, self-perceived depressive and anxiety distress, self-perceived health-related conditions, and healthy behaviors. Methods: 126 MDD outpatients and 106 healthy subjects were recruited. Self-reports of symptom distress, health-related conditions, and healthy behaviors and objective measures of salivary cortisol upon awakening, 45. min after awakening, and at 1200, 1700, and 2100. h were collected at subjects' homes. The individual growth curve model was used to manage data and to analyze repeated observations of self-report data associated with diurnal cortisol patterns. Results: For MDD outpatients, flatter diurnal cortisol patterns were more likely found in subjects with family histories of mental illness than in those without. Patient-reported shorter total sleep hours, more severe levels of depression and higher suffering levels were positively associated with flatter diurnal cortisol patterns. Less than 5 sleep hours was more likely associated with flatter diurnal cortisol patterns than above 7 sleep hours. Severe levels of depression were more likely related to flatter diurnal cortisol patterns than moderate and mild levels of depression. Higher anxiety levels, better sleep quality and higher levels of physical activity reported by patients were positively associated with steeper diurnal cortisol patterns. Unlike the MDD outpatients, the only trait associated with diurnal cortisol patterns in healthy subjects was total sleep hours. Conclusions: These results suggested that self-perceived good sleep quality, total hours slept of 7 or greater, and self-perceived higher levels of physical activity in the home environment could be positively related to positive stress endocrine outcomes seen as steep diurnal cortisol patterns in outpatients with major depressive disorder. © 2009 .
Persistent Identifierhttp://hdl.handle.net/10722/65471
ISSN
2015 Impact Factor: 4.704
2015 SCImago Journal Rankings: 2.740
ISI Accession Number ID
Funding AgencyGrant Number
National Science CouncilNSC94-2314-B-038-053
NSC 95-2314-B-038-045-MY2
Funding Information:

This study was supported by a grant from the National Science Council (NSC94-2314-B-038-053 and NSC 95-2314-B-038-045-MY2); the NSC had no further role in the study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the paper for publication.

References

 

DC FieldValueLanguage
dc.contributor.authorHsiao, FHen_HK
dc.contributor.authorYang, TTen_HK
dc.contributor.authorHo, RTHen_HK
dc.contributor.authorJow, GMen_HK
dc.contributor.authorNg, SMen_HK
dc.contributor.authorChan, CLWen_HK
dc.contributor.authorLai, YMen_HK
dc.contributor.authorChen, YTen_HK
dc.contributor.authorWang, KCen_HK
dc.date.accessioned2010-08-10T02:25:28Z-
dc.date.available2010-08-10T02:25:28Z-
dc.date.issued2010en_HK
dc.identifier.citationPsychoneuroendocrinology, 2010, v. 35 n. 4, p. 503-515en_HK
dc.identifier.issn0306-4530en_HK
dc.identifier.urihttp://hdl.handle.net/10722/65471-
dc.description.abstractObjective: This study was an examination of 126 major depressive disorder (MDD) outpatients' morning to evening diurnal cortisol patterns to determine their association with family histories of mental illness, self-perceived depressive and anxiety distress, self-perceived health-related conditions, and healthy behaviors. Methods: 126 MDD outpatients and 106 healthy subjects were recruited. Self-reports of symptom distress, health-related conditions, and healthy behaviors and objective measures of salivary cortisol upon awakening, 45. min after awakening, and at 1200, 1700, and 2100. h were collected at subjects' homes. The individual growth curve model was used to manage data and to analyze repeated observations of self-report data associated with diurnal cortisol patterns. Results: For MDD outpatients, flatter diurnal cortisol patterns were more likely found in subjects with family histories of mental illness than in those without. Patient-reported shorter total sleep hours, more severe levels of depression and higher suffering levels were positively associated with flatter diurnal cortisol patterns. Less than 5 sleep hours was more likely associated with flatter diurnal cortisol patterns than above 7 sleep hours. Severe levels of depression were more likely related to flatter diurnal cortisol patterns than moderate and mild levels of depression. Higher anxiety levels, better sleep quality and higher levels of physical activity reported by patients were positively associated with steeper diurnal cortisol patterns. Unlike the MDD outpatients, the only trait associated with diurnal cortisol patterns in healthy subjects was total sleep hours. Conclusions: These results suggested that self-perceived good sleep quality, total hours slept of 7 or greater, and self-perceived higher levels of physical activity in the home environment could be positively related to positive stress endocrine outcomes seen as steep diurnal cortisol patterns in outpatients with major depressive disorder. © 2009 .en_HK
dc.languageeng-
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/psyneuenen_HK
dc.relation.ispartofPsychoneuroendocrinologyen_HK
dc.subjectDepression levelsen_HK
dc.subjectMajor depressive disorderen_HK
dc.subjectSalivary cortisolen_HK
dc.subjectSleep hoursen_HK
dc.subjectSleep qualityen_HK
dc.subjectSuffering levelsen_HK
dc.subject.meshCircadian Rhythm - physiology-
dc.subject.meshDepressive Disorder, Major - metabolism - psychology-
dc.subject.meshHealth Status-
dc.subject.meshHydrocortisone - analysis - metabolism-
dc.subject.meshSelf Concept-
dc.titleThe self-perceived symptom distress and health-related conditions associated with morning to evening diurnal cortisol patterns in outpatients with major depressive disorderen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0306-4530&volume=35&issue=4&spage=503&epage=515&date=2009&atitle=The+self-perceived+symptoms+distress+and+health-related+conditions+associated+with+morning+to+evening+diurnal+cortisol+patterns+in+outpatients+with+major+depressive+disorder-
dc.identifier.emailHo, RTH: tinho@hku.hken_HK
dc.identifier.emailNg, SM: ngsiuman@hku.hken_HK
dc.identifier.emailChan, CLW: cecichan@hku.hken_HK
dc.identifier.authorityHo, RTH=rp00497en_HK
dc.identifier.authorityNg, SM=rp00611en_HK
dc.identifier.authorityChan, CLW=rp00579en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.psyneuen.2009.08.019en_HK
dc.identifier.pmid19775819-
dc.identifier.scopuseid_2-s2.0-77950689390en_HK
dc.identifier.hkuros170993-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77950689390&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume35en_HK
dc.identifier.issue4en_HK
dc.identifier.spage503en_HK
dc.identifier.epage515en_HK
dc.identifier.eissn1873-3360-
dc.identifier.isiWOS:000277222300003-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridHsiao, FH=7006744649en_HK
dc.identifier.scopusauthoridYang, TT=10241889500en_HK
dc.identifier.scopusauthoridHo, RTH=8620896500en_HK
dc.identifier.scopusauthoridJow, GM=6603159405en_HK
dc.identifier.scopusauthoridNg, SM=7403358478en_HK
dc.identifier.scopusauthoridChan, CLW=35274549700en_HK
dc.identifier.scopusauthoridLai, YM=7401512146en_HK
dc.identifier.scopusauthoridChen, YT=8929240400en_HK
dc.identifier.scopusauthoridWang, KC=24598349100en_HK
dc.identifier.citeulike5841494-

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