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Article: A comparison of the acceptance of immunochemical faecal occult blood test and colonoscopy in colorectal cancer screening: A prospective study among Chinese

TitleA comparison of the acceptance of immunochemical faecal occult blood test and colonoscopy in colorectal cancer screening: A prospective study among Chinese
Authors
KeywordsMedical sciences
Gastroenterology
Issue Date2010
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
Citation
Alimentary Pharmacology And Therapeutics, 2010, v. 32 n. 1, p. 74-82 How to Cite?
AbstractBackground Preferences to choose immunochemical faecal occult blood test (FIT) and colonoscopy as colorectal cancer (CRC) screening modalities among asymptomatic Chinese subjects remain unknown. Aim To evaluate the preference of choosing colonoscopy vs. FIT among CRC screening participants. Methods From a community-based CRC screening programme for asymptomatic Hong Kong Chinese aged 50-70 years, participants attended standardized educational sessions and chose the options of annual FIT for 5 years or direct colonoscopy once. Factors associated with choosing colonoscopy were evaluated by multivariate regression analysis. Results Among 3430 participants [mean age 56.8 years (s.d. 5.0); female 55.1%, male 44.9%], 51.3% chose colonoscopy and 48.7% chose FIT. Older participants (65-70 years) were less likely to choose colonoscopy [adjusted odds ratio (aOR) 0.731, P = 0.041]. Subjects who chose colonoscopy were those disagreed screening would lead to discomfort (aOR 1.356, P < 0.001), had relatives or friends who had CRC (first degree relatives aOR 1.679, P < 0.001; second degree relatives aOR 1.304, P = 0.019; friends or others aOR 1.252, P = 0.026) and those who self-perceived their health as poor (aOR 1.529, P = 0.025). Conclusions Faecal occult blood test and direct colonoscopy were equally preferable to Chinese. Colonoscopy was preferred among the younger subjects, those with positive family history of CRC and self-perceived poor health status. © 2010 Blackwell Publishing Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/65437
ISSN
2014 Impact Factor: 5.727
2013 SCImago Journal Rankings: 2.609
ISI Accession Number ID
Funding AgencyGrant Number
Hong Kong Jockey Club Charities Trust7103242
Funding Information:

Declaration of personal interests: Prof. Joseph Sung has served as a speaker for AstraZeneca, GSK and Nycomed, and an advisory board member for AstraZeneca, Schering Plough and Novartis. We thank all the participants who have contributed to this study. The abstract of this article was accepted for presentation by the United European Gastroenterology Week, 2009. Declaration of funding interests: This study was funded in full by the Hong Kong Jockey Club Charities Trust through the 'Bowel Cancer in Hong Kong: Education, Promotion and Screening' (project code: 7103242).

References

 

DC FieldValueLanguage
dc.contributor.authorWong, MCSen_HK
dc.contributor.authorTsoi, KKFen_HK
dc.contributor.authorNg, SSMen_HK
dc.contributor.authorLou, VWQen_HK
dc.contributor.authorChoi, SYPen_HK
dc.contributor.authorLing, KWKen_HK
dc.contributor.authorChan, FKLen_HK
dc.contributor.authorGriffiths, SMen_HK
dc.contributor.authorSung, JJYen_HK
dc.date.accessioned2010-08-05T02:18:55Z-
dc.date.available2010-08-05T02:18:55Z-
dc.date.issued2010en_HK
dc.identifier.citationAlimentary Pharmacology And Therapeutics, 2010, v. 32 n. 1, p. 74-82en_HK
dc.identifier.issn0269-2813en_HK
dc.identifier.urihttp://hdl.handle.net/10722/65437-
dc.description.abstractBackground Preferences to choose immunochemical faecal occult blood test (FIT) and colonoscopy as colorectal cancer (CRC) screening modalities among asymptomatic Chinese subjects remain unknown. Aim To evaluate the preference of choosing colonoscopy vs. FIT among CRC screening participants. Methods From a community-based CRC screening programme for asymptomatic Hong Kong Chinese aged 50-70 years, participants attended standardized educational sessions and chose the options of annual FIT for 5 years or direct colonoscopy once. Factors associated with choosing colonoscopy were evaluated by multivariate regression analysis. Results Among 3430 participants [mean age 56.8 years (s.d. 5.0); female 55.1%, male 44.9%], 51.3% chose colonoscopy and 48.7% chose FIT. Older participants (65-70 years) were less likely to choose colonoscopy [adjusted odds ratio (aOR) 0.731, P = 0.041]. Subjects who chose colonoscopy were those disagreed screening would lead to discomfort (aOR 1.356, P < 0.001), had relatives or friends who had CRC (first degree relatives aOR 1.679, P < 0.001; second degree relatives aOR 1.304, P = 0.019; friends or others aOR 1.252, P = 0.026) and those who self-perceived their health as poor (aOR 1.529, P = 0.025). Conclusions Faecal occult blood test and direct colonoscopy were equally preferable to Chinese. Colonoscopy was preferred among the younger subjects, those with positive family history of CRC and self-perceived poor health status. © 2010 Blackwell Publishing Ltd.en_HK
dc.languageeng-
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APTen_HK
dc.relation.ispartofAlimentary Pharmacology and Therapeuticsen_HK
dc.rightsAlimentary Pharmacology and Therapeutics. Copyright © Blackwell Publishing Ltd.-
dc.rightsThe definitive version is available at www.blackwell-synergy.com-
dc.subjectMedical sciences-
dc.subjectGastroenterology-
dc.titleA comparison of the acceptance of immunochemical faecal occult blood test and colonoscopy in colorectal cancer screening: A prospective study among Chineseen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0269-2813&volume=32&issue=1&spage=74&epage=82&date=2010&atitle=A+comparison+of+the+acceptance+of+immunochemical+faecal+occult+blood+test+and+colonoscopy+in+colorectal+cancer+screening:+a+prospective+study+among+Chinese-
dc.identifier.emailLou, VWQ: wlou@hkucc.hku.hken_HK
dc.identifier.authorityLou, VWQ=rp00607en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1365-2036.2010.04312.xen_HK
dc.identifier.pmid20345501en_HK
dc.identifier.scopuseid_2-s2.0-77953179576en_HK
dc.identifier.hkuros171237-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77953179576&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume32en_HK
dc.identifier.issue1en_HK
dc.identifier.spage74en_HK
dc.identifier.epage82en_HK
dc.identifier.isiWOS:000278393900009-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, MCS=16945015000en_HK
dc.identifier.scopusauthoridTsoi, KKF=16065259000en_HK
dc.identifier.scopusauthoridNg, SSM=26021413400en_HK
dc.identifier.scopusauthoridLou, VWQ=9846416500en_HK
dc.identifier.scopusauthoridChoi, SYP=8570383400en_HK
dc.identifier.scopusauthoridLing, KWK=37081168600en_HK
dc.identifier.scopusauthoridChan, FKL=7202586434en_HK
dc.identifier.scopusauthoridGriffiths, SM=35233240400en_HK
dc.identifier.scopusauthoridSung, JJY=35405352400en_HK

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