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Book Chapter: A Heuristic Method for Generating Probabilistic Boolean Networks from a Prescribed Transition Probability Matrix
Title | A Heuristic Method for Generating Probabilistic Boolean Networks from a Prescribed Transition Probability Matrix |
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Authors | |
Issue Date | 2008 |
Publisher | World Publishing Corporation. |
Citation | A Heuristic Method for Generating Probabilistic Boolean Networks from a Prescribed Transition Probability Matrix, In Zhang, X, Chen, L, Wu, L et al. (eds.), Optimization and Systems Biology-The Second International Symposium, OSB'08, Lijiang, China, October 31-November 3, 2008, Proceedings, p. 271-278. World Publishing Corporation, 2008 How to Cite? |
Abstract | Probabilistic Boolean Networks (PBNs) have received much attention for modeling genetic
regulatory networks. In this paper, we propose efficient algorithms for constructing a probabilistic
Boolean network when its transition probability matrix is given. This is an important inverse
problem in network inference from steady-state data, as most microarray data sets are assumed to
be obtained from sampling the steady-state. |
Persistent Identifier | http://hdl.handle.net/10722/64485 |
ISBN |
DC Field | Value | Language |
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dc.contributor.author | Ching, WK | en_HK |
dc.contributor.author | Chen, X | en_HK |
dc.contributor.author | Leung, HY | en_HK |
dc.contributor.author | Tsing, NK | en_HK |
dc.date.accessioned | 2010-07-13T04:51:50Z | - |
dc.date.available | 2010-07-13T04:51:50Z | - |
dc.date.issued | 2008 | en_HK |
dc.identifier.citation | A Heuristic Method for Generating Probabilistic Boolean Networks from a Prescribed Transition Probability Matrix, In Zhang, X, Chen, L, Wu, L et al. (eds.), Optimization and Systems Biology-The Second International Symposium, OSB'08, Lijiang, China, October 31-November 3, 2008, Proceedings, p. 271-278. World Publishing Corporation, 2008 | en_HK |
dc.identifier.isbn | 978-7-5062-9289-4/O639 | - |
dc.identifier.uri | http://hdl.handle.net/10722/64485 | - |
dc.description.abstract | Probabilistic Boolean Networks (PBNs) have received much attention for modeling genetic regulatory networks. In this paper, we propose efficient algorithms for constructing a probabilistic Boolean network when its transition probability matrix is given. This is an important inverse problem in network inference from steady-state data, as most microarray data sets are assumed to be obtained from sampling the steady-state. | - |
dc.language | eng | en_HK |
dc.publisher | World Publishing Corporation. | en_HK |
dc.relation.ispartof | Optimization and Systems Biology-The Second International Symposium, OSB'08, Lijiang, China, October 31-November 3, 2008, Proceedings | - |
dc.title | A Heuristic Method for Generating Probabilistic Boolean Networks from a Prescribed Transition Probability Matrix | en_HK |
dc.type | Book_Chapter | en_HK |
dc.identifier.email | Ching, WK: wching@HKUCC.hku.hk | en_HK |
dc.identifier.email | Chen, X: dlkcissy@hotmail.com | en_HK |
dc.identifier.email | Leung, HY: obliging@hkusua.hku.hk | en_HK |
dc.identifier.email | Tsing, NK: nktsing@hku.hk | en_HK |
dc.identifier.authority | Ching, WK=rp00679 | en_HK |
dc.identifier.authority | Tsing, NK=rp00794 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.hkuros | 153460 | en_HK |