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Conference Paper: 1H MRS of the visual cortex under chronic ocular hypertension
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Title1H MRS of the visual cortex under chronic ocular hypertension
 
AuthorsChan, KCW
So, KF
Wu, EX
 
Issue Date2009
 
PublisherInternational Society for Magnetic Resonance in Medicine.
 
CitationThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 349 [How to Cite?]
 
AbstractThis study aims to employ in vivo 1H MRS to monitor the metabolic changes in the visual cortex in an experimental model of chronic glaucoma. Five Sprague-Dawley rats were prepared to induce ocular hypertension unilaterally in the right eye by photocoagulating the episcleral and limbal veins using an argon laser. 1H MRS was performed to each side of the visual cortex 6 weeks after laser treatment. The results of this study suggest that glaucoma is associated with alterations in the metabolism of choline-containing compounds in the normally-appearing visual cortex. Measurement of the Cho:Cr reduction in the visual cortex may be a noninvasive biomarker for the disease.
 
DescriptionSession 36: Neurochemical Modeling & Profiling of Brain Metabolism - Oral presentation
 
ISBN9781615673384
 
DC FieldValue
dc.contributor.authorChan, KCW
 
dc.contributor.authorSo, KF
 
dc.contributor.authorWu, EX
 
dc.date.accessioned2010-07-13T03:54:55Z
 
dc.date.available2010-07-13T03:54:55Z
 
dc.date.issued2009
 
dc.description.abstractThis study aims to employ in vivo 1H MRS to monitor the metabolic changes in the visual cortex in an experimental model of chronic glaucoma. Five Sprague-Dawley rats were prepared to induce ocular hypertension unilaterally in the right eye by photocoagulating the episcleral and limbal veins using an argon laser. 1H MRS was performed to each side of the visual cortex 6 weeks after laser treatment. The results of this study suggest that glaucoma is associated with alterations in the metabolism of choline-containing compounds in the normally-appearing visual cortex. Measurement of the Cho:Cr reduction in the visual cortex may be a noninvasive biomarker for the disease.
 
dc.description.naturepublished_or_final_version
 
dc.descriptionSession 36: Neurochemical Modeling & Profiling of Brain Metabolism - Oral presentation
 
dc.description.otherThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 349
 
dc.identifier.citationThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 349 [How to Cite?]
 
dc.identifier.epage349
 
dc.identifier.hkuros162030
 
dc.identifier.isbn9781615673384
 
dc.identifier.spage349
 
dc.identifier.urihttp://hdl.handle.net/10722/62151
 
dc.languageeng
 
dc.publisherInternational Society for Magnetic Resonance in Medicine.
 
dc.publisher.placeUnited States
 
dc.relation.ispartofProceedings of ISMRM 17th Scientific Meeting & Exhibition
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.title1H MRS of the visual cortex under chronic ocular hypertension
 
dc.typeConference_Paper
 
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<description>Session 36: Neurochemical Modeling &amp; Profiling of Brain Metabolism - Oral presentation</description>
<description.abstract>This study aims to employ in vivo 1H MRS to monitor the metabolic changes in the visual cortex in an experimental model of chronic glaucoma. Five Sprague-Dawley rats were prepared to induce ocular hypertension unilaterally in the right eye by photocoagulating the episcleral and limbal veins using an argon laser. 1H MRS was performed to each side of the visual cortex 6 weeks after laser treatment. The results of this study suggest that glaucoma is associated with alterations in the metabolism of choline-containing compounds in the normally-appearing visual cortex. Measurement of the Cho:Cr reduction in the visual cortex may be a noninvasive biomarker for the disease.</description.abstract>
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