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Conference Paper: 1H MRS of the visual cortex under chronic ocular hypertension

Title1H MRS of the visual cortex under chronic ocular hypertension
Authors
Issue Date2009
PublisherInternational Society for Magnetic Resonance in Medicine.
Citation
The 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 349 How to Cite?
Abstract
This study aims to employ in vivo 1H MRS to monitor the metabolic changes in the visual cortex in an experimental model of chronic glaucoma. Five Sprague-Dawley rats were prepared to induce ocular hypertension unilaterally in the right eye by photocoagulating the episcleral and limbal veins using an argon laser. 1H MRS was performed to each side of the visual cortex 6 weeks after laser treatment. The results of this study suggest that glaucoma is associated with alterations in the metabolism of choline-containing compounds in the normally-appearing visual cortex. Measurement of the Cho:Cr reduction in the visual cortex may be a noninvasive biomarker for the disease.
DescriptionSession 36: Neurochemical Modeling & Profiling of Brain Metabolism - Oral presentation
Persistent Identifierhttp://hdl.handle.net/10722/62151
ISBN

 

DC FieldValueLanguage
dc.contributor.authorChan, KCWen_HK
dc.contributor.authorSo, KFen_HK
dc.contributor.authorWu, EXen_HK
dc.date.accessioned2010-07-13T03:54:55Z-
dc.date.available2010-07-13T03:54:55Z-
dc.date.issued2009en_HK
dc.identifier.citationThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 349en_HK
dc.identifier.isbn9781615673384-
dc.identifier.urihttp://hdl.handle.net/10722/62151-
dc.descriptionSession 36: Neurochemical Modeling & Profiling of Brain Metabolism - Oral presentation-
dc.description.abstractThis study aims to employ in vivo 1H MRS to monitor the metabolic changes in the visual cortex in an experimental model of chronic glaucoma. Five Sprague-Dawley rats were prepared to induce ocular hypertension unilaterally in the right eye by photocoagulating the episcleral and limbal veins using an argon laser. 1H MRS was performed to each side of the visual cortex 6 weeks after laser treatment. The results of this study suggest that glaucoma is associated with alterations in the metabolism of choline-containing compounds in the normally-appearing visual cortex. Measurement of the Cho:Cr reduction in the visual cortex may be a noninvasive biomarker for the disease.-
dc.languageengen_HK
dc.publisherInternational Society for Magnetic Resonance in Medicine.-
dc.relation.ispartofProceedings of ISMRM 17th Scientific Meeting & Exhibition-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.title1H MRS of the visual cortex under chronic ocular hypertensionen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailChan, KCW: kevin_ccw@hkusa.hku.hken_HK
dc.identifier.emailSo, KF: hrmaskf@hku.hk-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros162030en_HK
dc.identifier.spage349-
dc.identifier.epage349-
dc.publisher.placeUnited States-
dc.description.otherThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 349-

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