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Conference Paper: 1H MRS of the visual cortex under chronic ocular hypertension
| Title | 1H MRS of the visual cortex under chronic ocular hypertension |
|---|---|
| Authors | |
| Issue Date | 2009 |
| Publisher | International Society for Magnetic Resonance in Medicine. |
| Citation | The 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 349 How to Cite? |
| Abstract | This study aims to employ in vivo 1H MRS to monitor the metabolic changes in the visual cortex in an experimental model of chronic glaucoma. Five Sprague-Dawley rats were prepared to induce ocular hypertension unilaterally in the right eye by photocoagulating the episcleral and limbal veins using an argon laser. 1H MRS was performed to each side of the visual cortex 6 weeks after laser treatment. The results of this study suggest that glaucoma is associated with alterations in the metabolism of choline-containing compounds in the normally-appearing visual cortex. Measurement of the Cho:Cr reduction in the visual cortex may be a noninvasive biomarker for the disease. |
| Description | Session 36: Neurochemical Modeling & Profiling of Brain Metabolism - Oral presentation |
| Persistent Identifier | http://hdl.handle.net/10722/62151 |
| ISBN |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Chan, KCW | en_HK |
| dc.contributor.author | So, KF | en_HK |
| dc.contributor.author | Wu, EX | en_HK |
| dc.date.accessioned | 2010-07-13T03:54:55Z | - |
| dc.date.available | 2010-07-13T03:54:55Z | - |
| dc.date.issued | 2009 | en_HK |
| dc.identifier.citation | The 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 349 | en_HK |
| dc.identifier.isbn | 9781615673384 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/62151 | - |
| dc.description | Session 36: Neurochemical Modeling & Profiling of Brain Metabolism - Oral presentation | - |
| dc.description.abstract | This study aims to employ in vivo 1H MRS to monitor the metabolic changes in the visual cortex in an experimental model of chronic glaucoma. Five Sprague-Dawley rats were prepared to induce ocular hypertension unilaterally in the right eye by photocoagulating the episcleral and limbal veins using an argon laser. 1H MRS was performed to each side of the visual cortex 6 weeks after laser treatment. The results of this study suggest that glaucoma is associated with alterations in the metabolism of choline-containing compounds in the normally-appearing visual cortex. Measurement of the Cho:Cr reduction in the visual cortex may be a noninvasive biomarker for the disease. | - |
| dc.language | eng | en_HK |
| dc.publisher | International Society for Magnetic Resonance in Medicine. | - |
| dc.relation.ispartof | Proceedings of ISMRM 17th Scientific Meeting & Exhibition | - |
| dc.title | 1H MRS of the visual cortex under chronic ocular hypertension | en_HK |
| dc.type | Conference_Paper | en_HK |
| dc.identifier.email | Chan, KCW: kevin_ccw@hkusa.hku.hk | en_HK |
| dc.identifier.email | So, KF: hrmaskf@hku.hk | - |
| dc.identifier.email | Wu, EX: ewu@eee.hku.hk | - |
| dc.description.nature | published_or_final_version | - |
| dc.identifier.hkuros | 162030 | en_HK |
| dc.identifier.spage | 349 | - |
| dc.identifier.epage | 349 | - |
| dc.publisher.place | United States | - |
| dc.description.other | The 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 349 | - |