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Conference Paper: Does Kurtosis or Stretched-Exponential Model Fit Experimental Diffusion-Weighted Data Better?

TitleDoes Kurtosis or Stretched-Exponential Model Fit Experimental Diffusion-Weighted Data Better?
Authors
Issue Date2009
PublisherInternational Society of Magnetic Resonance in Medicine.
Citation
ISMRM 17th Annual Scientific Meeting & Exhibition, Honolulu, HI, 18-24 April 2009 How to Cite?
AbstractDiffusion-weighted (DW) signal dependence on b-value in neural tissues deviates from monoexponential decay. As a result, numerous models have been proposed to characterize such non-monoexponential decay. Two of them, namely kurtosis and stretched-exponential model, are of special interest. This study aimed to evaluate the performance of these two models in describing the experimental DW signals obtained from rodent brains in vivo. Our analysis demonstrates that the quadratic diffusion kurtosis model provides better fitting of DWI data, suggesting that DKI is a more accurate and robust diffusion model for characterizing the complex diffusion processes in vivo in neural tissue.
Persistent Identifierhttp://hdl.handle.net/10722/62113

 

DC FieldValueLanguage
dc.contributor.authorHui, SK-
dc.contributor.authorDing, AY-
dc.contributor.authorWu, EX-
dc.date.accessioned2010-07-13T03:54:09Z-
dc.date.available2010-07-13T03:54:09Z-
dc.date.issued2009-
dc.identifier.citationISMRM 17th Annual Scientific Meeting & Exhibition, Honolulu, HI, 18-24 April 2009-
dc.identifier.urihttp://hdl.handle.net/10722/62113-
dc.description.abstractDiffusion-weighted (DW) signal dependence on b-value in neural tissues deviates from monoexponential decay. As a result, numerous models have been proposed to characterize such non-monoexponential decay. Two of them, namely kurtosis and stretched-exponential model, are of special interest. This study aimed to evaluate the performance of these two models in describing the experimental DW signals obtained from rodent brains in vivo. Our analysis demonstrates that the quadratic diffusion kurtosis model provides better fitting of DWI data, suggesting that DKI is a more accurate and robust diffusion model for characterizing the complex diffusion processes in vivo in neural tissue.-
dc.languageeng-
dc.publisherInternational Society of Magnetic Resonance in Medicine.-
dc.relation.ispartof2009 Proceedings of International Society of Magnetic Resonance in Medicine-
dc.titleDoes Kurtosis or Stretched-Exponential Model Fit Experimental Diffusion-Weighted Data Better?-
dc.typeConference_Paper-
dc.identifier.emailHui, SK: edshui@hku.hk-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.authorityHui, SK=rp01832-
dc.identifier.authorityWu, EX=rp00193-
dc.identifier.hkuros162106-
dc.publisher.placeHonolulu, HI-

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