Conference Paper: Gas-filled microbubbles as intravascular susceptibility contrast agent for brain MRI

TitleGas-filled microbubbles as intravascular susceptibility contrast agent for brain MRI
Authors
Issue Date2009
PublisherInternational Society of Magnetic Resonance in Medicine.
Citation
The 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 1477 How to Cite?
AbstractGas-filled microbubbles have the potential to become a unique MR contrast agent due to their magnetic susceptibility effect, biocompatibility and localized manipulation via ultrasound cavitation. In this study, custom-made albumin-coated microbubbles and a commercially available lipid-based clinical ultrasound contrast agent SonoVue® were investigated with in vivo dynamic brain MRI in Sprague-Dawley rats at 7 Tesla. The results indicate that microbubbles can serve as an intravascular contrast agent for brain MRI at high field. Such microbubble MRI has the potential to provide real-time MRI guidance in various microbubble-based drug delivery and therapeutic applications.
DescriptionPerfusion & Permeability: DSC-MRI - Poster presentation
Persistent Identifierhttp://hdl.handle.net/10722/62102
ISBN

 

DC FieldValueLanguage
dc.contributor.authorCheung, JSCen_HK
dc.contributor.authorChow, AMKen_HK
dc.contributor.authorWu, EXen_HK
dc.date.accessioned2010-07-13T03:53:56Z-
dc.date.available2010-07-13T03:53:56Z-
dc.date.issued2009en_HK
dc.identifier.citationThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 1477en_HK
dc.identifier.isbn9781615673384-
dc.identifier.urihttp://hdl.handle.net/10722/62102-
dc.descriptionPerfusion & Permeability: DSC-MRI - Poster presentation-
dc.description.abstractGas-filled microbubbles have the potential to become a unique MR contrast agent due to their magnetic susceptibility effect, biocompatibility and localized manipulation via ultrasound cavitation. In this study, custom-made albumin-coated microbubbles and a commercially available lipid-based clinical ultrasound contrast agent SonoVue® were investigated with in vivo dynamic brain MRI in Sprague-Dawley rats at 7 Tesla. The results indicate that microbubbles can serve as an intravascular contrast agent for brain MRI at high field. Such microbubble MRI has the potential to provide real-time MRI guidance in various microbubble-based drug delivery and therapeutic applications.-
dc.languageengen_HK
dc.publisherInternational Society of Magnetic Resonance in Medicine.-
dc.relation.ispartofProceedings of ISMRM 17th Scientific Meeting & Exhibition-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleGas-filled microbubbles as intravascular susceptibility contrast agent for brain MRIen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailCheung, JSC: chungcsc@HKUSUA.hku.hk, chungcsc@gmail.comen_HK
dc.identifier.emailChow, AMK: aprilcmk@hkusua.hku.hk-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros162110en_HK
dc.identifier.spage1477-
dc.identifier.epage1477-
dc.publisher.placeUnited States-
dc.description.otherThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 1477-

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