File Download

Conference Paper: Characterization of cortex and white matter injury in a mild hypoxic-ischemic neonatal rat mode by diffusion tensor MR imaging

TitleCharacterization of cortex and white matter injury in a mild hypoxic-ischemic neonatal rat mode by diffusion tensor MR imaging
Authors
Issue Date2009
PublisherInternational Society of Magnetic Resonance in Medicine.
Citation
The 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 3594 How to Cite?
AbstractWe evaluated hypoxic-ischemic (HI) induced cortex and white matter (WM) damage in a mild HI neonatal rat model at 24h post HI by diffusion tensor MR imaging (DTI) and correlated the DTI indices with histological evaluations. Results showed that significantly decreased FA and ¦Ë// reflected HI induced astrogliosis in the injured cortex, whereas significantly decreased FA with increased ¦Ë¡Í indicated dysmyelination in the WM. Our results demonstrated that early mild HI induced cortex and WM damage could be reflected by DTI indices and these may be potentially useful biomarkers to non-invasively monitor mild HI induced neonatal brain damage.
DescriptionAnimal Studies: Diffusion & Perfusion - Poster presentation
Persistent Identifierhttp://hdl.handle.net/10722/62092
ISBN

 

DC FieldValueLanguage
dc.contributor.authorWang, Sen_HK
dc.contributor.authorWu, EXen_HK
dc.contributor.authorLau, HFen_HK
dc.contributor.authorKhong, PKen_HK
dc.date.accessioned2010-07-13T03:53:43Z-
dc.date.available2010-07-13T03:53:43Z-
dc.date.issued2009en_HK
dc.identifier.citationThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 3594en_HK
dc.identifier.isbn9781615673384-
dc.identifier.urihttp://hdl.handle.net/10722/62092-
dc.descriptionAnimal Studies: Diffusion & Perfusion - Poster presentation-
dc.description.abstractWe evaluated hypoxic-ischemic (HI) induced cortex and white matter (WM) damage in a mild HI neonatal rat model at 24h post HI by diffusion tensor MR imaging (DTI) and correlated the DTI indices with histological evaluations. Results showed that significantly decreased FA and ¦Ë// reflected HI induced astrogliosis in the injured cortex, whereas significantly decreased FA with increased ¦Ë¡Í indicated dysmyelination in the WM. Our results demonstrated that early mild HI induced cortex and WM damage could be reflected by DTI indices and these may be potentially useful biomarkers to non-invasively monitor mild HI induced neonatal brain damage.-
dc.languageengen_HK
dc.publisherInternational Society of Magnetic Resonance in Medicine.-
dc.relation.ispartofProceedings of ISMRM 17th Scientific Meeting & Exhibition-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleCharacterization of cortex and white matter injury in a mild hypoxic-ischemic neonatal rat mode by diffusion tensor MR imagingen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailWang, S: pkuwangsilun@yahoo.com.cnen_HK
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.emailLau, HF: lauhofai@gmail.com-
dc.identifier.emailKhong, PK: plkhong@hkucc.hku.hk-
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros162091en_HK
dc.identifier.spage3594-
dc.identifier.epage3594-
dc.publisher.placeUnited States-
dc.description.otherThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 3594-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats