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Conference Paper: Heart and liver R2 and R2* measurements in patients with thalassaemia major at 3T
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TitleHeart and liver R2 and R2* measurements in patients with thalassaemia major at 3T
 
AuthorsGuo, H
Au, WY
Cheung, JSC
Jensen, JH
Kim, D
Khong, PL
Chan, Q
Tosti, C
Tang, H
Brown, TR
Lam, WWM
Ha, SY
Brittenham, GM
Wu, EX
 
Issue Date2009
 
Publisherfor Magnetic Resonance in Medicine.
 
CitationThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 3752 [How to Cite?]
 
AbstractTo determine the feasibility of measurements of transverse relaxation times for assessment of tissue iron overload at high field, we compared results of determinations of R2 and R2* using breathhold multi-echo spin-echo (MESE) and multi-echo gradient echo (MEGE) sequences, respectively, at 3T and at 1.5T in normal subjects and patients with thalassaemia major. Our results, the first reported measurements of R2 at both 3T and 1.5T in iron overloaded patients, demonstrate significant correlations in heart and liver at the two field strengths. These results provide evidence that myocardial and hepatic R2 can be measured at 3T as indicators of iron overload.
 
DescriptionMyocardial Tissue Characterization: Fat, Hemorrhage & Edema - Poster presentation
 
ISBN9781615673384
 
DC FieldValue
dc.contributor.authorGuo, H
 
dc.contributor.authorAu, WY
 
dc.contributor.authorCheung, JSC
 
dc.contributor.authorJensen, JH
 
dc.contributor.authorKim, D
 
dc.contributor.authorKhong, PL
 
dc.contributor.authorChan, Q
 
dc.contributor.authorTosti, C
 
dc.contributor.authorTang, H
 
dc.contributor.authorBrown, TR
 
dc.contributor.authorLam, WWM
 
dc.contributor.authorHa, SY
 
dc.contributor.authorBrittenham, GM
 
dc.contributor.authorWu, EX
 
dc.date.accessioned2010-07-13T03:53:35Z
 
dc.date.available2010-07-13T03:53:35Z
 
dc.date.issued2009
 
dc.description.abstractTo determine the feasibility of measurements of transverse relaxation times for assessment of tissue iron overload at high field, we compared results of determinations of R2 and R2* using breathhold multi-echo spin-echo (MESE) and multi-echo gradient echo (MEGE) sequences, respectively, at 3T and at 1.5T in normal subjects and patients with thalassaemia major. Our results, the first reported measurements of R2 at both 3T and 1.5T in iron overloaded patients, demonstrate significant correlations in heart and liver at the two field strengths. These results provide evidence that myocardial and hepatic R2 can be measured at 3T as indicators of iron overload.
 
dc.description.naturepublished_or_final_version
 
dc.descriptionMyocardial Tissue Characterization: Fat, Hemorrhage & Edema - Poster presentation
 
dc.description.otherThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 3752
 
dc.identifier.citationThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 3752 [How to Cite?]
 
dc.identifier.epage3752
 
dc.identifier.hkuros162100
 
dc.identifier.isbn9781615673384
 
dc.identifier.spage3752
 
dc.identifier.urihttp://hdl.handle.net/10722/62085
 
dc.languageeng
 
dc.publisherfor Magnetic Resonance in Medicine.
 
dc.publisher.placeUnited States
 
dc.relation.ispartofProceedings of ISMRM 17th Scientific Meeting & Exhibition
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.titleHeart and liver R2 and R2* measurements in patients with thalassaemia major at 3T
 
dc.typeConference_Paper
 
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<contributor.author>Kim, D</contributor.author>
<contributor.author>Khong, PL</contributor.author>
<contributor.author>Chan, Q</contributor.author>
<contributor.author>Tosti, C</contributor.author>
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<description.abstract>To determine the feasibility of measurements of transverse relaxation times for assessment of tissue iron overload at high field, we compared results of determinations of R2 and R2* using breathhold multi-echo spin-echo (MESE) and multi-echo gradient echo (MEGE) sequences, respectively, at 3T and at 1.5T in normal subjects and patients with thalassaemia major. Our results, the first reported measurements of R2 at both 3T and 1.5T in iron overloaded patients, demonstrate significant correlations in heart and liver at the two field strengths. These results provide evidence that myocardial and hepatic R2 can be measured at 3T as indicators of iron overload.</description.abstract>
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