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Conference Paper: MRI detection of progenitor cell migrations during postnatal rat brain development by in situ MPIO labeling

TitleMRI detection of progenitor cell migrations during postnatal rat brain development by in situ MPIO labeling
Authors
Issue Date2009
PublisherInternational Society of Magnetic Resonance in Medicine.
Citation
The 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 3168 How to Cite?
Abstract
In this study, micron-sized iron oxide particles (MPIOs) were injected into the left anterior lateral ventricle of 10-day-old normal rats. T2- and T2*-weighted images were acquired using a 7T scanner at day 1, 3, 7 and 14 after the MPIO injection. Histological analyses were then performed to identify MPIOs in different migrating cells, namely, neural progenitor and astrocytes-like progenitor cells. The migrating pathways of the MPIO-labeled endogenous progenitors exhibited a predominantly bidirectional, rostrocaudal pattern in tangential orientation. Such in situ MPIO labeling approach opens the possibility of using MRI to study the mechanism of cell migration in developing brain.
DescriptionMolecules & Cells: Novel Applications - Poster presentation
Persistent Identifierhttp://hdl.handle.net/10722/62036
ISBN

 

DC FieldValueLanguage
dc.contributor.authorYang, Jen_HK
dc.contributor.authorLiu, Jen_HK
dc.contributor.authorNiu, Gen_HK
dc.contributor.authorWang, Ren_HK
dc.contributor.authorLiu, Yen_HK
dc.contributor.authorYu, Ben_HK
dc.contributor.authorWu, EXen_HK
dc.date.accessioned2010-07-13T03:52:35Z-
dc.date.available2010-07-13T03:52:35Z-
dc.date.issued2009en_HK
dc.identifier.citationThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 3168en_HK
dc.identifier.isbn9781615673384-
dc.identifier.urihttp://hdl.handle.net/10722/62036-
dc.descriptionMolecules & Cells: Novel Applications - Poster presentation-
dc.description.abstractIn this study, micron-sized iron oxide particles (MPIOs) were injected into the left anterior lateral ventricle of 10-day-old normal rats. T2- and T2*-weighted images were acquired using a 7T scanner at day 1, 3, 7 and 14 after the MPIO injection. Histological analyses were then performed to identify MPIOs in different migrating cells, namely, neural progenitor and astrocytes-like progenitor cells. The migrating pathways of the MPIO-labeled endogenous progenitors exhibited a predominantly bidirectional, rostrocaudal pattern in tangential orientation. Such in situ MPIO labeling approach opens the possibility of using MRI to study the mechanism of cell migration in developing brain.-
dc.languageengen_HK
dc.publisherInternational Society of Magnetic Resonance in Medicine.-
dc.relation.ispartofProceedings of ISMRM 17th Scientific Meeting & Exhibition-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleMRI detection of progenitor cell migrations during postnatal rat brain development by in situ MPIO labelingen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailYang, J: yj1118@hkucc.hku.hken_HK
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros162040en_HK
dc.identifier.spage3168-
dc.identifier.epage3168-
dc.publisher.placeUnited States-
dc.description.otherThe 17th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 18-24 April 2009. In Proceedings of ISMRM 17th Scientific Meeting & Exhibition, 2009, p. 3168-

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