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Conference Paper: Advanced MR diffusion characterization of neural tissue using directional diffusion kurtosis analysis.

TitleAdvanced MR diffusion characterization of neural tissue using directional diffusion kurtosis analysis.
Authors
Issue Date2008
PublisherIEEE. The Journal's web site is located at http://www.ieeexplore.ieee.org/xpl/conhome.jsp?punumber=1000269
Citation
Proceedings Of The 30Th Annual International Conference Of The Ieee Engineering In Medicine And Biology Society, Embs'08 - Personalized Healthcare Through Technology, 2008, p. 3941-3944 How to Cite?
AbstractMR Diffusion kurtosis imaging (DKI) was proposed recently to study the deviation of water diffusion from Gaussian distribution. Mean kurtosis (MK), directionally averaged kurtosis, has been shown to be useful in assessing pathophysilogical changes. However, MK is not sensitive to kurtosis change occurring along a specific direction. Therefore, orthogonal transformation of the 4th order kurtosis tensor was introduced in the current study to compute kurtoses along the 3 eigenvector directions of the 2nd order diffusion tensor. Such axial (K( parallel)) and radial (K perpendicular) kurtoses measured the kurtoses along the directions parallel and perpendicular, respectively, to the principal diffusion direction. DKI experiments were performed in normal adult and formalin-fixed rat brain, and developmental brains. The results showed that directional kurtosis analysis revealed different information for tissue characterization.
Descriptionproceedings of the IEEE Engineering in Medicine and Biology Society Conference, 2008, p. 3941-3944
Persistent Identifierhttp://hdl.handle.net/10722/61986
ISSN

 

DC FieldValueLanguage
dc.contributor.authorHui, ESen_HK
dc.contributor.authorCheung, MMen_HK
dc.contributor.authorQi, Len_HK
dc.contributor.authorWu, EXen_HK
dc.date.accessioned2010-07-13T03:51:34Z-
dc.date.available2010-07-13T03:51:34Z-
dc.date.issued2008en_HK
dc.identifier.citationProceedings Of The 30Th Annual International Conference Of The Ieee Engineering In Medicine And Biology Society, Embs'08 - Personalized Healthcare Through Technology, 2008, p. 3941-3944en_HK
dc.identifier.issn1557-170Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/61986-
dc.descriptionproceedings of the IEEE Engineering in Medicine and Biology Society Conference, 2008, p. 3941-3944en_HK
dc.description.abstractMR Diffusion kurtosis imaging (DKI) was proposed recently to study the deviation of water diffusion from Gaussian distribution. Mean kurtosis (MK), directionally averaged kurtosis, has been shown to be useful in assessing pathophysilogical changes. However, MK is not sensitive to kurtosis change occurring along a specific direction. Therefore, orthogonal transformation of the 4th order kurtosis tensor was introduced in the current study to compute kurtoses along the 3 eigenvector directions of the 2nd order diffusion tensor. Such axial (K( parallel)) and radial (K perpendicular) kurtoses measured the kurtoses along the directions parallel and perpendicular, respectively, to the principal diffusion direction. DKI experiments were performed in normal adult and formalin-fixed rat brain, and developmental brains. The results showed that directional kurtosis analysis revealed different information for tissue characterization.en_HK
dc.languageengen_HK
dc.publisherIEEE. The Journal's web site is located at http://www.ieeexplore.ieee.org/xpl/conhome.jsp?punumber=1000269-
dc.relation.ispartofProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"en_HK
dc.rightsIEEE Engineering in Medicine and Biology Society. Conference Proceedings. Copyright © IEEE.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rights©2008 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.-
dc.subject.meshAnimals-
dc.subject.meshBrain - anatomy and histology - metabolism - pathology-
dc.subject.meshImage Interpretation, Computer-Assisted - methods-
dc.subject.meshImaging, Three-Dimensional - methods-
dc.subject.meshWater - metabolism-
dc.titleAdvanced MR diffusion characterization of neural tissue using directional diffusion kurtosis analysis.en_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1557-170X&volume=&spage=3941&epage=3944&date=2008&atitle=Advanced+MR+diffusion+characterization+of+neural+tissue+using+directional+diffusion+kurtosis+analysis-
dc.identifier.emailWu, EX:ewu1@hkucc.hku.hken_HK
dc.identifier.authorityWu, EX=rp00193en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1109/IEMBS.2008.4650072-
dc.identifier.pmid19163575-
dc.identifier.scopuseid_2-s2.0-61849164596en_HK
dc.identifier.hkuros161994en_HK
dc.identifier.volume2008en_HK
dc.identifier.spage3941en_HK
dc.identifier.epage3944en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHui, ES=16175117100en_HK
dc.identifier.scopusauthoridCheung, MM=24333907800en_HK
dc.identifier.scopusauthoridQi, L=7202149952en_HK
dc.identifier.scopusauthoridWu, EX=7202128034en_HK

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