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Article: Correlation between microaneurysms and retinal thickness in diabetic macular edema

TitleCorrelation between microaneurysms and retinal thickness in diabetic macular edema
Authors
KeywordsBlood-retinal barrier
Diabetic retinopathy
Macular edema
Microaneurysms
Retinal thickness analysis
Issue Date2008
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.retinajournal.com
Citation
Retina, 2008, v. 28 n. 8, p. 1097-1103 How to Cite?
AbstractPURPOSE: Microaneurysms commonly are believed to be related causally to retinal thickening in diabetic retinopathy, especially by leaking. The hypothesis that thicker areas of retina in diabetic retinopathy have more microaneurysms per unit area than areas that are not as thick was tested. METHODS: Retinal thickness analysis was performed with a prototype instrument for 27 eyes of 27 diabetic patients and 22 normal eyes of 22 healthy subjects. Maps of retinal thickness were created, and microaneurysms were counted in zones having four levels of retinal thickness. RESULTS: There was no increase in either total microaneurysms or apparent leaking microaneurysms per unit area with increasing levels of retinal thickness (P = 0.77 and 0.87, respectively). CONCLUSION: Some microaneurysms may not cause thickening, or other factors may contribute to retinal thickening in diabetic retinopathy. The results may have implications on the pathogenesis of diabetic macular edema. Copyright © 2008 by the Ophthalmic Communication Society Inc.
Persistent Identifierhttp://hdl.handle.net/10722/60910
ISSN
2015 Impact Factor: 3.039
2015 SCImago Journal Rankings: 1.912
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorBlair, NPen_HK
dc.contributor.authorShahidi, Men_HK
dc.contributor.authorLai, WWen_HK
dc.contributor.authorZelkha, Ren_HK
dc.date.accessioned2010-05-31T04:21:38Z-
dc.date.available2010-05-31T04:21:38Z-
dc.date.issued2008en_HK
dc.identifier.citationRetina, 2008, v. 28 n. 8, p. 1097-1103en_HK
dc.identifier.issn0275-004Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/60910-
dc.description.abstractPURPOSE: Microaneurysms commonly are believed to be related causally to retinal thickening in diabetic retinopathy, especially by leaking. The hypothesis that thicker areas of retina in diabetic retinopathy have more microaneurysms per unit area than areas that are not as thick was tested. METHODS: Retinal thickness analysis was performed with a prototype instrument for 27 eyes of 27 diabetic patients and 22 normal eyes of 22 healthy subjects. Maps of retinal thickness were created, and microaneurysms were counted in zones having four levels of retinal thickness. RESULTS: There was no increase in either total microaneurysms or apparent leaking microaneurysms per unit area with increasing levels of retinal thickness (P = 0.77 and 0.87, respectively). CONCLUSION: Some microaneurysms may not cause thickening, or other factors may contribute to retinal thickening in diabetic retinopathy. The results may have implications on the pathogenesis of diabetic macular edema. Copyright © 2008 by the Ophthalmic Communication Society Inc.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.retinajournal.comen_HK
dc.relation.ispartofRetinaen_HK
dc.rightsRetina. Copyright © Lippincott Williams & Wilkins.en_HK
dc.subjectBlood-retinal barrieren_HK
dc.subjectDiabetic retinopathyen_HK
dc.subjectMacular edemaen_HK
dc.subjectMicroaneurysmsen_HK
dc.subjectRetinal thickness analysisen_HK
dc.titleCorrelation between microaneurysms and retinal thickness in diabetic macular edemaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0275-004X&volume=28&spage=1097&epage=1103&date=2008&atitle=Correlation+between+microaneurysms+and+retinal+thickness+in+diabetic+macular+edemaen_HK
dc.identifier.emailLai, WW: wicolai@hku.hken_HK
dc.identifier.authorityLai, WW=rp00531en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/IAE.0b013e318177f8ecen_HK
dc.identifier.scopuseid_2-s2.0-58149232449en_HK
dc.identifier.hkuros149722en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58149232449&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume28en_HK
dc.identifier.issue8en_HK
dc.identifier.spage1097en_HK
dc.identifier.epage1103en_HK
dc.identifier.isiWOS:000259329100010-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridBlair, NP=7005095959en_HK
dc.identifier.scopusauthoridShahidi, M=7003985405en_HK
dc.identifier.scopusauthoridLai, WW=7402231098en_HK
dc.identifier.scopusauthoridZelkha, R=6507335792en_HK

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