File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Retinotopically Specific Reorganization of Visual Cortex for Tactile Pattern Recognition

TitleRetinotopically Specific Reorganization of Visual Cortex for Tactile Pattern Recognition
Authors
KeywordsSYSNEURO
Issue Date2009
PublisherCell Press. The Journal's web site is located at http://www.current-biology.com/
Citation
Current Biology, 2009, v. 19 n. 7, p. 596-601 How to Cite?
AbstractAlthough previous studies have shown that Braille reading and other tactile discrimination tasks activate the visual cortex of blind and sighted people [1-5], it is not known whether this kind of crossmodal reorganization is influenced by retinotopic organization. We have addressed this question by studying "S," a visually impaired adult with the rare ability to read print visually and Braille by touch. S had normal visual development until 6 years of age, and thereafter severe acuity reduction due to corneal opacification, but no evidence of visual-field loss. Functional magnetic resonance imaging revealed that, in S's early visual areas, tactile information processing activated what would be the foveal representation for normally sighted individuals, and visual information processing activated what would be the peripheral representation. Control experiments showed that this activation pattern was not due to visual imagery. S's high-level visual areas, which correspond to shape- and object-selective areas in normally sighted individuals, were activated by both visual and tactile stimuli. The retinotopically specific reorganization in early visual areas suggests an efficient redistribution of neural resources in the visual cortex. © 2009 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/60738
ISSN
2015 Impact Factor: 8.983
2015 SCImago Journal Rankings: 4.729
PubMed Central ID
ISI Accession Number ID
Funding AgencyGrant Number
University of Minnesota Doctoral Dissertation Fellowship
US National Institutes of Health (NIH)EY002934
NIH National Center for Research Resources (NCRR)P41 RR008079
Mental Illness and Neuroscience Discovery (MIND) Institute
Funding Information:

"S" is author G.E.L. We thank Thomas A. Carlson and Serena Thompson for assistance in data collection, Deyue Yu for conducting the tangent-field measurements on S, Allen M.Y. Cheong for conducting the fixation stability measurements on S, and Scott O. Murray and Bosco S. Tian for comments on earlier drafts of this manuscript. This study was supported by a University of Minnesota Doctoral Dissertation Fellowship to S.-H.C. and US National Institutes of Health (NIH) grant EY002934 to G.E.L. Use of the 3T magnetic resonance scanner at the Center for Magnetic Resonance Research of the University of Minnesota was supported by NIH National Center for Research Resources (NCRR) grant P41 RR008079 and the Mental Illness and Neuroscience Discovery (MIND) Institute.

References

 

DC FieldValueLanguage
dc.contributor.authorCheung, SHen_HK
dc.contributor.authorFang, Fen_HK
dc.contributor.authorHe, Sen_HK
dc.contributor.authorLegge, GEen_HK
dc.date.accessioned2010-05-31T04:17:31Z-
dc.date.available2010-05-31T04:17:31Z-
dc.date.issued2009en_HK
dc.identifier.citationCurrent Biology, 2009, v. 19 n. 7, p. 596-601en_HK
dc.identifier.issn0960-9822en_HK
dc.identifier.urihttp://hdl.handle.net/10722/60738-
dc.description.abstractAlthough previous studies have shown that Braille reading and other tactile discrimination tasks activate the visual cortex of blind and sighted people [1-5], it is not known whether this kind of crossmodal reorganization is influenced by retinotopic organization. We have addressed this question by studying "S," a visually impaired adult with the rare ability to read print visually and Braille by touch. S had normal visual development until 6 years of age, and thereafter severe acuity reduction due to corneal opacification, but no evidence of visual-field loss. Functional magnetic resonance imaging revealed that, in S's early visual areas, tactile information processing activated what would be the foveal representation for normally sighted individuals, and visual information processing activated what would be the peripheral representation. Control experiments showed that this activation pattern was not due to visual imagery. S's high-level visual areas, which correspond to shape- and object-selective areas in normally sighted individuals, were activated by both visual and tactile stimuli. The retinotopically specific reorganization in early visual areas suggests an efficient redistribution of neural resources in the visual cortex. © 2009 Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherCell Press. The Journal's web site is located at http://www.current-biology.com/en_HK
dc.relation.ispartofCurrent Biologyen_HK
dc.subjectSYSNEUROen_HK
dc.titleRetinotopically Specific Reorganization of Visual Cortex for Tactile Pattern Recognitionen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0960-9822&volume=19&spage=596&epage=601&date=2009&atitle=Retinotopically+specific+reorganization+of+visual+cortex+for+tactile+pattern+recognitionen_HK
dc.identifier.emailCheung, SH:singhang@hku.hken_HK
dc.identifier.authorityCheung, SH=rp00590en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1016/j.cub.2009.02.063en_HK
dc.identifier.pmid19361999-
dc.identifier.pmcidPMC2709730-
dc.identifier.scopuseid_2-s2.0-64049098090en_HK
dc.identifier.hkuros155412en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-64049098090&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume19en_HK
dc.identifier.issue7en_HK
dc.identifier.spage596en_HK
dc.identifier.epage601en_HK
dc.identifier.isiWOS:000265266900030-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridCheung, SH=7202473508en_HK
dc.identifier.scopusauthoridFang, F=7202929817en_HK
dc.identifier.scopusauthoridHe, S=7402691306en_HK
dc.identifier.scopusauthoridLegge, GE=7005064208en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats