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Article: Temporal proteomic analysis of intestine developing necrotizing enterocolitis following enteral formula feeding to preterm pigs

TitleTemporal proteomic analysis of intestine developing necrotizing enterocolitis following enteral formula feeding to preterm pigs
Authors
Jiang, PSangild, PTSit, WHNgai, HHYXu, RSiggers, JLAWan, JMF
Keywords2-DE
Enteral formula feeding
Mass spectrometry
Necrotizing enterocolitis
Premature neonates
Temporal study
Issue Date2009
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jprobs
Citation
Journal Of Proteome Research, 2009, v. 8 n. 1, p. 72-81 How to Cite?
DOI: http://dx.doi.org/10.1021/pr800638w
AbstractNecrotizing enterocolitis (NEC), a serious gastrointestinal inflammatory disease, frequently occurs in preterm neonates that fail to adapt to enteral nutrition. A temporal gel-based proteomics study was performed on porcine intestine with NEC lesions induced by enteral formula feeding. Functional assignment of the differentially expressed proteins revealed that important cellular functions, such as the heat shock response, protein processing; and purine, nitrogen, energy metabolism, were possible involved in the early progression of NEC. © 2003 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/60697
ISSN
1535-3893
2021 Impact Factor: 5.370
2020 SCImago Journal Rankings: 1.644
ISI Accession Number ID
WOS:000262171100008
Funding AgencyGrant Number
University of Hong Kong
Danish Research Councils
Funding Information:

This work is supported by The University of Hong Kong and the Danish Research Councils.

References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorJiang, Pen_HK
dc.contributor.authorSangild, PTen_HK
dc.contributor.authorSit, WHen_HK
dc.contributor.authorNgai, HHYen_HK
dc.contributor.authorXu, Ren_HK
dc.contributor.authorSiggers, JLAen_HK
dc.contributor.authorWan, JMFen_HK
dc.date.accessioned2010-05-31T04:16:42Z-
dc.date.available2010-05-31T04:16:42Z-
dc.date.issued2009en_HK
dc.identifier.citationJournal Of Proteome Research, 2009, v. 8 n. 1, p. 72-81en_HK
dc.identifier.issn1535-3893en_HK
dc.identifier.urihttp://hdl.handle.net/10722/60697-
dc.description.abstractNecrotizing enterocolitis (NEC), a serious gastrointestinal inflammatory disease, frequently occurs in preterm neonates that fail to adapt to enteral nutrition. A temporal gel-based proteomics study was performed on porcine intestine with NEC lesions induced by enteral formula feeding. Functional assignment of the differentially expressed proteins revealed that important cellular functions, such as the heat shock response, protein processing; and purine, nitrogen, energy metabolism, were possible involved in the early progression of NEC. © 2003 American Chemical Society.en_HK
dc.languageengen_HK
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jprobsen_HK
dc.relation.ispartofJournal of Proteome Researchen_HK
dc.subject2-DEen_HK
dc.subjectEnteral formula feedingen_HK
dc.subjectMass spectrometryen_HK
dc.subjectNecrotizing enterocolitisen_HK
dc.subjectPremature neonatesen_HK
dc.subjectTemporal studyen_HK
dc.titleTemporal proteomic analysis of intestine developing necrotizing enterocolitis following enteral formula feeding to preterm pigsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1535-3893&volume=8&spage=72&epage=81&date=2008&atitle=Temporal+Proteomic+Analysis+of+Intestine+Developing+Necrotizing+Enterocolitis+following+Enteral+Formula+Feeding+to+Preterm+Pigsen_HK
dc.identifier.emailXu, R: xuruojun@hkucc.hku.hken_HK
dc.identifier.emailWan, JMF: jmfwan@hku.hken_HK
dc.identifier.authorityXu, R=rp00820en_HK
dc.identifier.authorityWan, JMF=rp00798en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1021/pr800638wen_HK
dc.identifier.pmid18983181-
dc.identifier.scopuseid_2-s2.0-60849113168en_HK
dc.identifier.hkuros154354en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-60849113168&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume8en_HK
dc.identifier.issue1en_HK
dc.identifier.spage72en_HK
dc.identifier.epage81en_HK
dc.identifier.eissn1535-3907-
dc.identifier.isiWOS:000262171100008-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridJiang, P=36147603700en_HK
dc.identifier.scopusauthoridSangild, PT=7004115316en_HK
dc.identifier.scopusauthoridSit, WH=8528923000en_HK
dc.identifier.scopusauthoridNgai, HHY=8528923200en_HK
dc.identifier.scopusauthoridXu, R=7402813973en_HK
dc.identifier.scopusauthoridSiggers, JLA=24554223000en_HK
dc.identifier.scopusauthoridWan, JMF=8930305000en_HK
dc.identifier.issnl1535-3893-

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