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Article: Phylogenetic evidence for homologous recombination within the family Birnaviridae

TitlePhylogenetic evidence for homologous recombination within the family Birnaviridae
Authors
Issue Date2008
PublisherSociety for General Microbiology. The Journal's web site is located at http://vir.sgmjournals.org
Citation
Journal Of General Virology, 2008, v. 89 n. 12, p. 3156-3164 How to Cite?
AbstractBirnaviruses are bi-segmented double-stranded RNA (dsRNA) viruses infecting insects, avian species and a wide range of aquatic species. Although homologous recombination is a common phenomenon in positive-sense RNA viruses, recombination in dsRNA viruses is rarely reported. Here we performed a comprehensive survey on homologous recombination in all available sequences (>1800) of the family Birnaviridae based on phylogenetic incongruence. Although inter-species recombination was not evident, potential intra-species recombination events were detected in aquabirnaviruses and infectious bursal disease virus (IBDV). Eight potential recombination events were identified and the possibility that these events were non-naturally occurring was assessed case by case. Five of the eight events were identified in IBDVs and all of these five events involved live attenuated vaccine strains. This finding suggests that homologous recombination between vaccine and wild-type IBDV strains may have occurred; the potential risk of mass vaccination using live vaccines is discussed. This is the first report of evidence for homologous recombination within the family Birnaviridae. © 2008 SGM.
Persistent Identifierhttp://hdl.handle.net/10722/60696
ISSN
2015 Impact Factor: 3.192
2015 SCImago Journal Rankings: 1.741
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHon, CCen_HK
dc.contributor.authorLam, TTYen_HK
dc.contributor.authorYip, CWen_HK
dc.contributor.authorWong, RTYen_HK
dc.contributor.authorShi, Men_HK
dc.contributor.authorJiang, Jen_HK
dc.contributor.authorZeng, Fen_HK
dc.contributor.authorLeung, FCCen_HK
dc.date.accessioned2010-05-31T04:16:41Z-
dc.date.available2010-05-31T04:16:41Z-
dc.date.issued2008en_HK
dc.identifier.citationJournal Of General Virology, 2008, v. 89 n. 12, p. 3156-3164en_HK
dc.identifier.issn0022-1317en_HK
dc.identifier.urihttp://hdl.handle.net/10722/60696-
dc.description.abstractBirnaviruses are bi-segmented double-stranded RNA (dsRNA) viruses infecting insects, avian species and a wide range of aquatic species. Although homologous recombination is a common phenomenon in positive-sense RNA viruses, recombination in dsRNA viruses is rarely reported. Here we performed a comprehensive survey on homologous recombination in all available sequences (>1800) of the family Birnaviridae based on phylogenetic incongruence. Although inter-species recombination was not evident, potential intra-species recombination events were detected in aquabirnaviruses and infectious bursal disease virus (IBDV). Eight potential recombination events were identified and the possibility that these events were non-naturally occurring was assessed case by case. Five of the eight events were identified in IBDVs and all of these five events involved live attenuated vaccine strains. This finding suggests that homologous recombination between vaccine and wild-type IBDV strains may have occurred; the potential risk of mass vaccination using live vaccines is discussed. This is the first report of evidence for homologous recombination within the family Birnaviridae. © 2008 SGM.en_HK
dc.languageengen_HK
dc.publisherSociety for General Microbiology. The Journal's web site is located at http://vir.sgmjournals.orgen_HK
dc.relation.ispartofJournal of General Virologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsJournal of General Virology. Copyright © Society for General Microbiology.-
dc.subject.meshAmino Acid Sequence-
dc.subject.meshAnimals-
dc.subject.meshBirnaviridae - classification - genetics-
dc.subject.meshPhylogeny-
dc.subject.meshRecombination, Genetic-
dc.titlePhylogenetic evidence for homologous recombination within the family Birnaviridaeen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-1317&volume=89&issue=12&spage=3156&epage=3164&date=2008&atitle=Phylogenetic+evidence+for+homologous+recombination+within+the+family+Birnaviridaeen_HK
dc.identifier.emailLam, TTY: ttylam@hku.hken_HK
dc.identifier.emailLeung, FCC: fcleung@hkucc.hku.hken_HK
dc.identifier.authorityLam, TTY=rp01733en_HK
dc.identifier.authorityLeung, FCC=rp00731en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1099/vir.0.2008/004101-0en_HK
dc.identifier.pmid19008406en_HK
dc.identifier.scopuseid_2-s2.0-58149393398en_HK
dc.identifier.hkuros166172en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58149393398&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume89en_HK
dc.identifier.issue12en_HK
dc.identifier.spage3156en_HK
dc.identifier.epage3164en_HK
dc.identifier.isiWOS:000261527800030-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridHon, CC=7003617137en_HK
dc.identifier.scopusauthoridLam, TTY=36775821700en_HK
dc.identifier.scopusauthoridYip, CW=7101665559en_HK
dc.identifier.scopusauthoridWong, RTY=24759484000en_HK
dc.identifier.scopusauthoridShi, M=25951822000en_HK
dc.identifier.scopusauthoridJiang, J=35310401200en_HK
dc.identifier.scopusauthoridZeng, F=7202911544en_HK
dc.identifier.scopusauthoridLeung, FCC=7103078633en_HK

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