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Article: Moderate Alcohol Use, Health Status, and Mortality in a Prospective Chinese Elderly Cohort

TitleModerate Alcohol Use, Health Status, and Mortality in a Prospective Chinese Elderly Cohort
Authors
Issue Date2009
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/annepidem
Citation
Annals Of Epidemiology, 2009, v. 19 n. 6, p. 396-403 How to Cite?
AbstractPurpose: A U-shaped relation between alcohol use and mortality may be due to biological hormesis, differential response (i.e., effect modification) by health status or changes in alcohol use with ill-health and aging (i.e., reverse causality).We examined whether alcohol had the same association with mortality in healthy and unhealthy older people. Methods: We used Cox regression analysis to examine the association of alcohol with mortality by health status in a population-based cohort of 56,167 people (65+ years), enrolled during July 1998 to December 2000 in Hong Kong. Results: After a mean follow-up of 4.1 years, there were 3,819 deaths in 54,087 subjects. Adjusted for age, socioeconomic position and lifestyle, both occasional and moderate types of alcohol use were associated with lower mortality compared to never-drinkers, relative risk (RR) 0.72 (95% confidence interval [CI] 0.63-0.83) and 0.73 (95% CI 0.59-0.90) in men and 0.77 (95% CI 0.64-0.94) and 0.54 (95% CI 0.29-1.01) in women. However, these associations were not maintained in those with good health status: RR 1.02 (95% CI 0.74-1.39) and 1.09 (95% CI 0.71-1.68) in men and 0.63 (95% CI 0.36-1.12) and 1.27 (95% CI 0.40-4.01) in women. Conclusions: Moderate alcohol use may only be beneficial for older adults in poor health. © 2009 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/60299
ISSN
2015 Impact Factor: 2.335
2015 SCImago Journal Rankings: 1.439
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorSun, Wen_HK
dc.contributor.authorSchooling, CMen_HK
dc.contributor.authorChan, WMen_HK
dc.contributor.authorHo, KSen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorLeung, GMen_HK
dc.date.accessioned2010-05-31T04:07:50Z-
dc.date.available2010-05-31T04:07:50Z-
dc.date.issued2009en_HK
dc.identifier.citationAnnals Of Epidemiology, 2009, v. 19 n. 6, p. 396-403en_HK
dc.identifier.issn1047-2797en_HK
dc.identifier.urihttp://hdl.handle.net/10722/60299-
dc.description.abstractPurpose: A U-shaped relation between alcohol use and mortality may be due to biological hormesis, differential response (i.e., effect modification) by health status or changes in alcohol use with ill-health and aging (i.e., reverse causality).We examined whether alcohol had the same association with mortality in healthy and unhealthy older people. Methods: We used Cox regression analysis to examine the association of alcohol with mortality by health status in a population-based cohort of 56,167 people (65+ years), enrolled during July 1998 to December 2000 in Hong Kong. Results: After a mean follow-up of 4.1 years, there were 3,819 deaths in 54,087 subjects. Adjusted for age, socioeconomic position and lifestyle, both occasional and moderate types of alcohol use were associated with lower mortality compared to never-drinkers, relative risk (RR) 0.72 (95% confidence interval [CI] 0.63-0.83) and 0.73 (95% CI 0.59-0.90) in men and 0.77 (95% CI 0.64-0.94) and 0.54 (95% CI 0.29-1.01) in women. However, these associations were not maintained in those with good health status: RR 1.02 (95% CI 0.74-1.39) and 1.09 (95% CI 0.71-1.68) in men and 0.63 (95% CI 0.36-1.12) and 1.27 (95% CI 0.40-4.01) in women. Conclusions: Moderate alcohol use may only be beneficial for older adults in poor health. © 2009 Elsevier Inc. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/annepidemen_HK
dc.relation.ispartofAnnals of Epidemiologyen_HK
dc.rightsAnnals of Epidemiology. Copyright © Elsevier Inc.en_HK
dc.subject.meshAgeden_HK
dc.subject.meshAged, 80 and overen_HK
dc.subject.meshAlcohol Drinking - epidemiology - mortalityen_HK
dc.subject.meshAsian Continental Ancestry Group - statistics & numerical dataen_HK
dc.subject.meshCause of Deathen_HK
dc.subject.meshDemographyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHealth Statusen_HK
dc.subject.meshHealth Surveysen_HK
dc.subject.meshHong Kong - epidemiologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshProspective Studiesen_HK
dc.titleModerate Alcohol Use, Health Status, and Mortality in a Prospective Chinese Elderly Cohorten_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1047-2797&volume=19&issue=6&spage=396&epage=403&date=2009&atitle=Moderate+alcohol+use,+health+status,+and+mortality+in+a+prospective+Chinese+elderly+cohorten_HK
dc.identifier.emailSchooling, CM:cms1@hkucc.hku.hken_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.emailLeung, GM:gmleung@hku.hken_HK
dc.identifier.authoritySchooling, CM=rp00504en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.annepidem.2009.01.011en_HK
dc.identifier.pmid19460670en_HK
dc.identifier.scopuseid_2-s2.0-65549086019en_HK
dc.identifier.hkuros155685en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-65549086019&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume19en_HK
dc.identifier.issue6en_HK
dc.identifier.spage396en_HK
dc.identifier.epage403en_HK
dc.identifier.isiWOS:000266648000006-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridSun, W=18635452400en_HK
dc.identifier.scopusauthoridSchooling, CM=12808565000en_HK
dc.identifier.scopusauthoridChan, WM=7403914485en_HK
dc.identifier.scopusauthoridHo, KS=7403581605en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK
dc.identifier.citeulike5331861-

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