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- Publisher Website: 10.1016/j.annepidem.2009.01.011
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- PMID: 19460670
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Article: Moderate Alcohol Use, Health Status, and Mortality in a Prospective Chinese Elderly Cohort
Title | Moderate Alcohol Use, Health Status, and Mortality in a Prospective Chinese Elderly Cohort |
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Authors | |
Keywords | Alcohol Chinese Health Status Mortality Old |
Issue Date | 2009 |
Publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/annepidem |
Citation | Annals Of Epidemiology, 2009, v. 19 n. 6, p. 396-403 How to Cite? |
Abstract | Purpose: A U-shaped relation between alcohol use and mortality may be due to biological hormesis, differential response (i.e., effect modification) by health status or changes in alcohol use with ill-health and aging (i.e., reverse causality).We examined whether alcohol had the same association with mortality in healthy and unhealthy older people. Methods: We used Cox regression analysis to examine the association of alcohol with mortality by health status in a population-based cohort of 56,167 people (65+ years), enrolled during July 1998 to December 2000 in Hong Kong. Results: After a mean follow-up of 4.1 years, there were 3,819 deaths in 54,087 subjects. Adjusted for age, socioeconomic position and lifestyle, both occasional and moderate types of alcohol use were associated with lower mortality compared to never-drinkers, relative risk (RR) 0.72 (95% confidence interval [CI] 0.63-0.83) and 0.73 (95% CI 0.59-0.90) in men and 0.77 (95% CI 0.64-0.94) and 0.54 (95% CI 0.29-1.01) in women. However, these associations were not maintained in those with good health status: RR 1.02 (95% CI 0.74-1.39) and 1.09 (95% CI 0.71-1.68) in men and 0.63 (95% CI 0.36-1.12) and 1.27 (95% CI 0.40-4.01) in women. Conclusions: Moderate alcohol use may only be beneficial for older adults in poor health. © 2009 Elsevier Inc. All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/60299 |
ISSN | 2023 Impact Factor: 3.3 2023 SCImago Journal Rankings: 1.382 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Sun, W | en_HK |
dc.contributor.author | Schooling, CM | en_HK |
dc.contributor.author | Chan, WM | en_HK |
dc.contributor.author | Ho, KS | en_HK |
dc.contributor.author | Lam, TH | en_HK |
dc.contributor.author | Leung, GM | en_HK |
dc.date.accessioned | 2010-05-31T04:07:50Z | - |
dc.date.available | 2010-05-31T04:07:50Z | - |
dc.date.issued | 2009 | en_HK |
dc.identifier.citation | Annals Of Epidemiology, 2009, v. 19 n. 6, p. 396-403 | en_HK |
dc.identifier.issn | 1047-2797 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/60299 | - |
dc.description.abstract | Purpose: A U-shaped relation between alcohol use and mortality may be due to biological hormesis, differential response (i.e., effect modification) by health status or changes in alcohol use with ill-health and aging (i.e., reverse causality).We examined whether alcohol had the same association with mortality in healthy and unhealthy older people. Methods: We used Cox regression analysis to examine the association of alcohol with mortality by health status in a population-based cohort of 56,167 people (65+ years), enrolled during July 1998 to December 2000 in Hong Kong. Results: After a mean follow-up of 4.1 years, there were 3,819 deaths in 54,087 subjects. Adjusted for age, socioeconomic position and lifestyle, both occasional and moderate types of alcohol use were associated with lower mortality compared to never-drinkers, relative risk (RR) 0.72 (95% confidence interval [CI] 0.63-0.83) and 0.73 (95% CI 0.59-0.90) in men and 0.77 (95% CI 0.64-0.94) and 0.54 (95% CI 0.29-1.01) in women. However, these associations were not maintained in those with good health status: RR 1.02 (95% CI 0.74-1.39) and 1.09 (95% CI 0.71-1.68) in men and 0.63 (95% CI 0.36-1.12) and 1.27 (95% CI 0.40-4.01) in women. Conclusions: Moderate alcohol use may only be beneficial for older adults in poor health. © 2009 Elsevier Inc. All rights reserved. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/annepidem | en_HK |
dc.relation.ispartof | Annals of Epidemiology | en_HK |
dc.rights | Annals of Epidemiology. Copyright © Elsevier Inc. | en_HK |
dc.subject | Alcohol | - |
dc.subject | Chinese | - |
dc.subject | Health Status | - |
dc.subject | Mortality | - |
dc.subject | Old | - |
dc.subject.mesh | Aged | en_HK |
dc.subject.mesh | Aged, 80 and over | en_HK |
dc.subject.mesh | Alcohol Drinking - epidemiology - mortality | en_HK |
dc.subject.mesh | Asian Continental Ancestry Group - statistics & numerical data | en_HK |
dc.subject.mesh | Cause of Death | en_HK |
dc.subject.mesh | Demography | en_HK |
dc.subject.mesh | Female | en_HK |
dc.subject.mesh | Health Status | en_HK |
dc.subject.mesh | Health Surveys | en_HK |
dc.subject.mesh | Hong Kong - epidemiology | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Male | en_HK |
dc.subject.mesh | Prospective Studies | en_HK |
dc.title | Moderate Alcohol Use, Health Status, and Mortality in a Prospective Chinese Elderly Cohort | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1047-2797&volume=19&issue=6&spage=396&epage=403&date=2009&atitle=Moderate+alcohol+use,+health+status,+and+mortality+in+a+prospective+Chinese+elderly+cohort | en_HK |
dc.identifier.email | Schooling, CM:cms1@hkucc.hku.hk | en_HK |
dc.identifier.email | Lam, TH:hrmrlth@hkucc.hku.hk | en_HK |
dc.identifier.email | Leung, GM:gmleung@hku.hk | en_HK |
dc.identifier.authority | Schooling, CM=rp00504 | en_HK |
dc.identifier.authority | Lam, TH=rp00326 | en_HK |
dc.identifier.authority | Leung, GM=rp00460 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.annepidem.2009.01.011 | en_HK |
dc.identifier.pmid | 19460670 | en_HK |
dc.identifier.scopus | eid_2-s2.0-65549086019 | en_HK |
dc.identifier.hkuros | 155685 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-65549086019&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 19 | en_HK |
dc.identifier.issue | 6 | en_HK |
dc.identifier.spage | 396 | en_HK |
dc.identifier.epage | 403 | en_HK |
dc.identifier.isi | WOS:000266648000006 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Sun, W=18635452400 | en_HK |
dc.identifier.scopusauthorid | Schooling, CM=12808565000 | en_HK |
dc.identifier.scopusauthorid | Chan, WM=7403914485 | en_HK |
dc.identifier.scopusauthorid | Ho, KS=7403581605 | en_HK |
dc.identifier.scopusauthorid | Lam, TH=7202522876 | en_HK |
dc.identifier.scopusauthorid | Leung, GM=7007159841 | en_HK |
dc.identifier.citeulike | 5331861 | - |
dc.identifier.issnl | 1047-2797 | - |