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Article: COPD-related morbidity and mortality after smoking cessation: Status of the evidence

TitleCOPD-related morbidity and mortality after smoking cessation: Status of the evidence
Authors
Issue Date2008
PublisherEuropean Respiratory Society. The Journal's web site is located at http://erj.ersjournals.com
Citation
European Respiratory Journal, 2008, v. 32 n. 4, p. 844-853 How to Cite?
AbstractThe evidence base for the benefit of quitting smoking as regards morbidity and mortality outcomes in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) is limited. The present article is a review of the existing literature. A systematic literature search in medical databases was performed until March 2006, and subsequently until September 1, 2007. The outcomes examined were COPD-related morbidity and mortality (including all-cause mortality) in COPD patients in connection with smoking cessation. A total of 21 and 27 published articles on morbidity and mortality, respectively, were identified and reviewed. For both outcomes, only a few of the studies included patients with severe COPD. Most of the studies reported a beneficial effect of smoking cessation compared with continued smoking, whereas a few found no improvement. Methodological problems, including small study sizes, poor data quality, possibility of reverse causality and incomplete ascertainment of cause of death, limit interpretation of some of the studies. The evidence as a whole supports the conclusion that, even in severe chronic obstructive pulmonary disease, smoking cessation slows the accelerated rate of lung function decline and improves survival compared with continued smoking. Copyright©ERS Journals Ltd 2008.
Persistent Identifierhttp://hdl.handle.net/10722/60281
ISSN
2015 Impact Factor: 8.332
2015 SCImago Journal Rankings: 3.204
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorGodtfredsen, NSen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorHansel, TTen_HK
dc.contributor.authorLeon, MEen_HK
dc.contributor.authorGray, Nen_HK
dc.contributor.authorDresler, Cen_HK
dc.contributor.authorBurns, DMen_HK
dc.contributor.authorPrescott, Een_HK
dc.contributor.authorVestbo, Jen_HK
dc.date.accessioned2010-05-31T04:07:29Z-
dc.date.available2010-05-31T04:07:29Z-
dc.date.issued2008en_HK
dc.identifier.citationEuropean Respiratory Journal, 2008, v. 32 n. 4, p. 844-853en_HK
dc.identifier.issn0903-1936en_HK
dc.identifier.urihttp://hdl.handle.net/10722/60281-
dc.description.abstractThe evidence base for the benefit of quitting smoking as regards morbidity and mortality outcomes in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) is limited. The present article is a review of the existing literature. A systematic literature search in medical databases was performed until March 2006, and subsequently until September 1, 2007. The outcomes examined were COPD-related morbidity and mortality (including all-cause mortality) in COPD patients in connection with smoking cessation. A total of 21 and 27 published articles on morbidity and mortality, respectively, were identified and reviewed. For both outcomes, only a few of the studies included patients with severe COPD. Most of the studies reported a beneficial effect of smoking cessation compared with continued smoking, whereas a few found no improvement. Methodological problems, including small study sizes, poor data quality, possibility of reverse causality and incomplete ascertainment of cause of death, limit interpretation of some of the studies. The evidence as a whole supports the conclusion that, even in severe chronic obstructive pulmonary disease, smoking cessation slows the accelerated rate of lung function decline and improves survival compared with continued smoking. Copyright©ERS Journals Ltd 2008.en_HK
dc.languageengen_HK
dc.publisherEuropean Respiratory Society. The Journal's web site is located at http://erj.ersjournals.comen_HK
dc.relation.ispartofEuropean Respiratory Journalen_HK
dc.subject.meshAdolescenten_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAtherosclerosisen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshProportional Hazards Modelsen_HK
dc.subject.meshPulmonary Disease, Chronic Obstructive - mortality - physiopathology - therapyen_HK
dc.subject.meshRisken_HK
dc.subject.meshSmokingen_HK
dc.subject.meshSmoking Cessationen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.titleCOPD-related morbidity and mortality after smoking cessation: Status of the evidenceen_HK
dc.typeArticleen_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1183/09031936.00160007en_HK
dc.identifier.pmid18827152-
dc.identifier.scopuseid_2-s2.0-58849113557en_HK
dc.identifier.hkuros152873en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58849113557&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume32en_HK
dc.identifier.issue4en_HK
dc.identifier.spage844en_HK
dc.identifier.epage853en_HK
dc.identifier.isiWOS:000259944500005-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridGodtfredsen, NS=6601958065en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridHansel, TT=7006490149en_HK
dc.identifier.scopusauthoridLeon, ME=26023420000en_HK
dc.identifier.scopusauthoridGray, N=35394365400en_HK
dc.identifier.scopusauthoridDresler, C=7006818388en_HK
dc.identifier.scopusauthoridBurns, DM=7403172241en_HK
dc.identifier.scopusauthoridPrescott, E=15036718700en_HK
dc.identifier.scopusauthoridVestbo, J=34573970200en_HK

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