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Article: In silico prediction of two classes of honeybee genes with cpG deficiency or cpG enrichment and sorting according to gene ontology classes

TitleIn silico prediction of two classes of honeybee genes with cpG deficiency or cpG enrichment and sorting according to gene ontology classes
Authors
KeywordsCpG deficiency
DNA methylation
Gene Ontology classes
Honeybee
Issue Date2009
PublisherSpringer New York LLC. The Journal's web site is located at http://link.springer.de/link/service/journals/00239
Citation
Journal Of Molecular Evolution, 2009, v. 68 n. 6, p. 700-705 How to Cite?
AbstractTwo honeybee DNA methyltransferase genes have recently been identified and confirmed to be functional. The honeybee genes under regulation by DNA methylation may therefore be CpG deficient, due to natural deamination of methylated DNA. In this report, we show that <39% of the known honeybee genes are likely to be methylated on the basis of their low CpG obs/exp ratios. In contrast, orthologues of these genes in the fruitfly do not show CpG deficiency. Classes of function as determined by Gene Ontology were obtained for the honeybee genes with significantly low and high CpG obs/exp ratios. Overrepresented classes in the low CpG[obs/exp] genes are involved in transcription, translation, protein folding, protein localization, protein transportation, cell cycle, and DNA and RNA metabolism. © 2009 Springer Science+Business Media, LLC.
Persistent Identifierhttp://hdl.handle.net/10722/60135
ISSN
2015 Impact Factor: 1.847
2015 SCImago Journal Rankings: 0.952
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWang, Yen_HK
dc.contributor.authorLeung, FCCen_HK
dc.date.accessioned2010-05-31T04:04:20Z-
dc.date.available2010-05-31T04:04:20Z-
dc.date.issued2009en_HK
dc.identifier.citationJournal Of Molecular Evolution, 2009, v. 68 n. 6, p. 700-705en_HK
dc.identifier.issn0022-2844en_HK
dc.identifier.urihttp://hdl.handle.net/10722/60135-
dc.description.abstractTwo honeybee DNA methyltransferase genes have recently been identified and confirmed to be functional. The honeybee genes under regulation by DNA methylation may therefore be CpG deficient, due to natural deamination of methylated DNA. In this report, we show that <39% of the known honeybee genes are likely to be methylated on the basis of their low CpG obs/exp ratios. In contrast, orthologues of these genes in the fruitfly do not show CpG deficiency. Classes of function as determined by Gene Ontology were obtained for the honeybee genes with significantly low and high CpG obs/exp ratios. Overrepresented classes in the low CpG[obs/exp] genes are involved in transcription, translation, protein folding, protein localization, protein transportation, cell cycle, and DNA and RNA metabolism. © 2009 Springer Science+Business Media, LLC.en_HK
dc.languageengen_HK
dc.publisherSpringer New York LLC. The Journal's web site is located at http://link.springer.de/link/service/journals/00239en_HK
dc.relation.ispartofJournal of Molecular Evolutionen_HK
dc.subjectCpG deficiencyen_HK
dc.subjectDNA methylationen_HK
dc.subjectGene Ontology classesen_HK
dc.subjectHoneybeeen_HK
dc.titleIn silico prediction of two classes of honeybee genes with cpG deficiency or cpG enrichment and sorting according to gene ontology classesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-2844&volume=68&issue=6&spage=700&epage=705&date=2009&atitle=In+Silico+Prediction+Of+Two+Classes+Of+Honeybee+Genes+With+Cpg+Deficiency+Or+Cpg+Enrichment+And+Sorting+According+To+Gene+Ontology+Classesen_HK
dc.identifier.emailLeung, FCC: fcleung@hkucc.hku.hken_HK
dc.identifier.authorityLeung, FCC=rp00731en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00239-009-9244-3en_HK
dc.identifier.pmid19466376-
dc.identifier.scopuseid_2-s2.0-67349164022en_HK
dc.identifier.hkuros166188en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67349164022&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume68en_HK
dc.identifier.issue6en_HK
dc.identifier.spage700en_HK
dc.identifier.epage705en_HK
dc.identifier.isiWOS:000266781200010-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWang, Y=7601487776en_HK
dc.identifier.scopusauthoridLeung, FCC=7103078633en_HK

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