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Article: Comparison of outcome of open and laparoscopic resection for stage II and stage III rectal cancer

TitleComparison of outcome of open and laparoscopic resection for stage II and stage III rectal cancer
Authors
Issue Date2009
PublisherSpringer New York LLC. The Journal's web site is located at http://www.annalssurgicaloncology.org
Citation
Annals Of Surgical Oncology, 2009, v. 16 n. 6, p. 1488-1493 How to Cite?
AbstractBackground: Laparoscopic resection for advanced rectal cancer has not been widely accepted, and there are only few studies with survival data. This study aimed to compare the survival of patients who underwent laparoscopic and open resection for stage II and III rectal cancer. Materials and Methods: Consecutive patients (open resection: n = 310; laparoscopic resection: n = 111) who underwent curative resection for stage II and III rectal cancer from June 2000 to December 2006 were included. The operative details, postoperative complications, postoperative outcomes, and survival data were collected prospectively. Comparison was made between patients who had laparoscopic and open surgery. Results: The age, gender, medical morbidity, types of operation, and American Society of Anesthesiologists (ASA) status were similar between the two groups. There was also no difference in the mortality, morbidity, and pathological staging. Laparoscopic resection was associated with significantly less blood loss and shorter hospital stay. With the median follow-up of 34 months, there was no difference in local recurrence rates. The 5-year actuarial survivals were 71.1% and 59.3% in the laparoscopic and open groups, respectively (P = .029). In the multivariate analysis, laparoscopic resection was one of the independent significant factors associated with better survival (P = .03, hazards ratio: 0.558, 95% confidence interval: 0.339-0.969). Other independent poor prognostic factors included lymph node metastasis, poor differentiation, perineural invasion, presence of postoperative complications, and no chemotherapy. Conclusions: Laparoscopic resection for locally advanced rectal cancer is associated with more favorable overall survival when compared with open resection. © 2009 Society of Surgical Oncology.
Persistent Identifierhttp://hdl.handle.net/10722/59954
ISSN
2015 Impact Factor: 3.655
2015 SCImago Journal Rankings: 1.902
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLaw, WLen_HK
dc.contributor.authorPoon, JTCen_HK
dc.contributor.authorFan, JKMen_HK
dc.contributor.authorLo, SHen_HK
dc.date.accessioned2010-05-31T04:00:49Z-
dc.date.available2010-05-31T04:00:49Z-
dc.date.issued2009en_HK
dc.identifier.citationAnnals Of Surgical Oncology, 2009, v. 16 n. 6, p. 1488-1493en_HK
dc.identifier.issn1068-9265en_HK
dc.identifier.urihttp://hdl.handle.net/10722/59954-
dc.description.abstractBackground: Laparoscopic resection for advanced rectal cancer has not been widely accepted, and there are only few studies with survival data. This study aimed to compare the survival of patients who underwent laparoscopic and open resection for stage II and III rectal cancer. Materials and Methods: Consecutive patients (open resection: n = 310; laparoscopic resection: n = 111) who underwent curative resection for stage II and III rectal cancer from June 2000 to December 2006 were included. The operative details, postoperative complications, postoperative outcomes, and survival data were collected prospectively. Comparison was made between patients who had laparoscopic and open surgery. Results: The age, gender, medical morbidity, types of operation, and American Society of Anesthesiologists (ASA) status were similar between the two groups. There was also no difference in the mortality, morbidity, and pathological staging. Laparoscopic resection was associated with significantly less blood loss and shorter hospital stay. With the median follow-up of 34 months, there was no difference in local recurrence rates. The 5-year actuarial survivals were 71.1% and 59.3% in the laparoscopic and open groups, respectively (P = .029). In the multivariate analysis, laparoscopic resection was one of the independent significant factors associated with better survival (P = .03, hazards ratio: 0.558, 95% confidence interval: 0.339-0.969). Other independent poor prognostic factors included lymph node metastasis, poor differentiation, perineural invasion, presence of postoperative complications, and no chemotherapy. Conclusions: Laparoscopic resection for locally advanced rectal cancer is associated with more favorable overall survival when compared with open resection. © 2009 Society of Surgical Oncology.en_HK
dc.languageengen_HK
dc.publisherSpringer New York LLC. The Journal's web site is located at http://www.annalssurgicaloncology.orgen_HK
dc.relation.ispartofAnnals of Surgical Oncologyen_HK
dc.rightsThe original publication is available at www.springerlink.com-
dc.subject.meshColectomy - methods-
dc.subject.meshLaparoscopy-
dc.subject.meshRectal Neoplasms - mortality - pathology - surgery-
dc.subject.meshSurvival Analysis-
dc.subject.meshTreatment Outcome-
dc.titleComparison of outcome of open and laparoscopic resection for stage II and stage III rectal canceren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1068-9265&volume=16&issue=6&spage=1488&epage=1493&date=2009&atitle=Comparison+of+outcome+of+open+and+laparoscopic+resection+for+stage+II+and+stage+III+rectal+canceren_HK
dc.identifier.emailLaw, WL: lawwl@hkucc.hku.hken_HK
dc.identifier.emailPoon, JTC: tcjensen@hkucc.hku.hken_HK
dc.identifier.authorityLaw, WL=rp00436en_HK
dc.identifier.authorityPoon, JTC=rp01603en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1245/s10434-009-0418-4en_HK
dc.identifier.pmid19290491-
dc.identifier.scopuseid_2-s2.0-67349104388en_HK
dc.identifier.hkuros161522en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67349104388&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue6en_HK
dc.identifier.spage1488en_HK
dc.identifier.epage1493en_HK
dc.identifier.eissn1534-4681-
dc.identifier.isiWOS:000265787200009-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLaw, WL=7103147867en_HK
dc.identifier.scopusauthoridPoon, JTC=7005903722en_HK
dc.identifier.scopusauthoridFan, JKM=23484820100en_HK
dc.identifier.scopusauthoridLo, SH=15518872700en_HK
dc.identifier.citeulike4200017-

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