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Conference Paper: Role of branched-chain amino acids in management of cirrhosis and hepatocellular carcinoma

TitleRole of branched-chain amino acids in management of cirrhosis and hepatocellular carcinoma
Authors
KeywordsBranched-chain amino acids
Cirrhosis
Hepatic encephalopathy
Hepatocellular carcinoma
Liver transplantation
Issue Date2008
PublisherBlackwell Publishing Ltd
Citation
Hepatology Research, 2008, v. 38 SUPPL. 1, p. S107-S115 How to Cite?
Abstract
Altered protein and energy metabolism is a hallmark of chronic liver disease, characterized by decreased plasma branched-chain amino acids (BCAA) and increased plasma aromatic amino acids (AAA). Overwhelming evidence has indicated that the incidence of complications of chronic liver disease increases with malnutrition. Hence nutritional management in patients with chronic liver disease must receive high priority. The use of BCAA supplementation has been a controversial subject. This review summarizes published results of BCAA supplementation as a nutritional therapy for patients with cirrhosis and hepatocellular carcinoma (HCC). On balance, it would be appropriate to conclude that BCAA are associated with decreased frequency of complications of cirrhosis and improved nutritional status when prescribed as a maintenance therapy for patients with cirrhosis. More studies are, however, required to identify those who might benefit most from BCAA supplementation. © 2008 The Japan Society of Hepatology.
Persistent Identifierhttp://hdl.handle.net/10722/59928
ISSN
2013 Impact Factor: 2.218
2013 SCImago Journal Rankings: 0.923
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLam, VWen_HK
dc.contributor.authorPoon, RTen_HK
dc.date.accessioned2010-05-31T04:00:19Z-
dc.date.available2010-05-31T04:00:19Z-
dc.date.issued2008en_HK
dc.identifier.citationHepatology Research, 2008, v. 38 SUPPL. 1, p. S107-S115en_HK
dc.identifier.issn1386-6346en_HK
dc.identifier.urihttp://hdl.handle.net/10722/59928-
dc.description.abstractAltered protein and energy metabolism is a hallmark of chronic liver disease, characterized by decreased plasma branched-chain amino acids (BCAA) and increased plasma aromatic amino acids (AAA). Overwhelming evidence has indicated that the incidence of complications of chronic liver disease increases with malnutrition. Hence nutritional management in patients with chronic liver disease must receive high priority. The use of BCAA supplementation has been a controversial subject. This review summarizes published results of BCAA supplementation as a nutritional therapy for patients with cirrhosis and hepatocellular carcinoma (HCC). On balance, it would be appropriate to conclude that BCAA are associated with decreased frequency of complications of cirrhosis and improved nutritional status when prescribed as a maintenance therapy for patients with cirrhosis. More studies are, however, required to identify those who might benefit most from BCAA supplementation. © 2008 The Japan Society of Hepatology.en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Ltden_HK
dc.relation.ispartofHepatology Researchen_HK
dc.rightsHepatology Research. Copyright © Blackwell Publishing Ltd.en_HK
dc.subjectBranched-chain amino acidsen_HK
dc.subjectCirrhosisen_HK
dc.subjectHepatic encephalopathyen_HK
dc.subjectHepatocellular carcinomaen_HK
dc.subjectLiver transplantationen_HK
dc.titleRole of branched-chain amino acids in management of cirrhosis and hepatocellular carcinomaen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1386-6346&volume=38&issue=Suppl. 1&spage=S107&epage=S115&date=2008&atitle=Role+of+branched-chain+amino+acids+in+management+of+cirrhosis+and+hepatocellular+carcinomaen_HK
dc.identifier.emailPoon, RT: poontp@hkucc.hku.hken_HK
dc.identifier.authorityPoon, RT=rp00446en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1872-034X.2008.00435.xen_HK
dc.identifier.pmid19125941-
dc.identifier.scopuseid_2-s2.0-58049084242en_HK
dc.identifier.hkuros167036en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58049084242&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume38en_HK
dc.identifier.issueSUPPL. 1en_HK
dc.identifier.spageS107en_HK
dc.identifier.epageS115en_HK
dc.identifier.isiWOS:000261713100019-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridLam, VW=14828037100en_HK
dc.identifier.scopusauthoridPoon, RT=7103097223en_HK

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