File Download
 
Links for fulltext
(May Require Subscription)
 
Supplementary

Conference Paper: Role of branched-chain amino acids in management of cirrhosis and hepatocellular carcinoma
  • Basic View
  • Metadata View
  • XML View
TitleRole of branched-chain amino acids in management of cirrhosis and hepatocellular carcinoma
 
AuthorsLam, VW1 2
Poon, RT1
 
KeywordsBranched-chain amino acids
Cirrhosis
Hepatic encephalopathy
Hepatocellular carcinoma
Liver transplantation
 
Issue Date2008
 
PublisherBlackwell Publishing Ltd
 
CitationHepatology Research, 2008, v. 38 SUPPL. 1, p. S107-S115 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1872-034X.2008.00435.x
 
AbstractAltered protein and energy metabolism is a hallmark of chronic liver disease, characterized by decreased plasma branched-chain amino acids (BCAA) and increased plasma aromatic amino acids (AAA). Overwhelming evidence has indicated that the incidence of complications of chronic liver disease increases with malnutrition. Hence nutritional management in patients with chronic liver disease must receive high priority. The use of BCAA supplementation has been a controversial subject. This review summarizes published results of BCAA supplementation as a nutritional therapy for patients with cirrhosis and hepatocellular carcinoma (HCC). On balance, it would be appropriate to conclude that BCAA are associated with decreased frequency of complications of cirrhosis and improved nutritional status when prescribed as a maintenance therapy for patients with cirrhosis. More studies are, however, required to identify those who might benefit most from BCAA supplementation. © 2008 The Japan Society of Hepatology.
 
ISSN1386-6346
2013 Impact Factor: 2.218
2013 SCImago Journal Rankings: 0.923
 
DOIhttp://dx.doi.org/10.1111/j.1872-034X.2008.00435.x
 
ISI Accession Number IDWOS:000261713100019
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorLam, VW
 
dc.contributor.authorPoon, RT
 
dc.date.accessioned2010-05-31T04:00:19Z
 
dc.date.available2010-05-31T04:00:19Z
 
dc.date.issued2008
 
dc.description.abstractAltered protein and energy metabolism is a hallmark of chronic liver disease, characterized by decreased plasma branched-chain amino acids (BCAA) and increased plasma aromatic amino acids (AAA). Overwhelming evidence has indicated that the incidence of complications of chronic liver disease increases with malnutrition. Hence nutritional management in patients with chronic liver disease must receive high priority. The use of BCAA supplementation has been a controversial subject. This review summarizes published results of BCAA supplementation as a nutritional therapy for patients with cirrhosis and hepatocellular carcinoma (HCC). On balance, it would be appropriate to conclude that BCAA are associated with decreased frequency of complications of cirrhosis and improved nutritional status when prescribed as a maintenance therapy for patients with cirrhosis. More studies are, however, required to identify those who might benefit most from BCAA supplementation. © 2008 The Japan Society of Hepatology.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationHepatology Research, 2008, v. 38 SUPPL. 1, p. S107-S115 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1872-034X.2008.00435.x
 
dc.identifier.doihttp://dx.doi.org/10.1111/j.1872-034X.2008.00435.x
 
dc.identifier.epageS115
 
dc.identifier.hkuros167036
 
dc.identifier.isiWOS:000261713100019
 
dc.identifier.issn1386-6346
2013 Impact Factor: 2.218
2013 SCImago Journal Rankings: 0.923
 
dc.identifier.issueSUPPL. 1
 
dc.identifier.openurl
 
dc.identifier.pmid19125941
 
dc.identifier.scopuseid_2-s2.0-58049084242
 
dc.identifier.spageS107
 
dc.identifier.urihttp://hdl.handle.net/10722/59928
 
dc.identifier.volume38
 
dc.languageeng
 
dc.publisherBlackwell Publishing Ltd
 
dc.publisher.placeIreland
 
dc.relation.ispartofHepatology Research
 
dc.relation.referencesReferences in Scopus
 
dc.rightsHepatology Research. Copyright © Blackwell Publishing Ltd.
 
dc.subjectBranched-chain amino acids
 
dc.subjectCirrhosis
 
dc.subjectHepatic encephalopathy
 
dc.subjectHepatocellular carcinoma
 
dc.subjectLiver transplantation
 
dc.titleRole of branched-chain amino acids in management of cirrhosis and hepatocellular carcinoma
 
dc.typeConference_Paper
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Lam, VW</contributor.author>
<contributor.author>Poon, RT</contributor.author>
<date.accessioned>2010-05-31T04:00:19Z</date.accessioned>
<date.available>2010-05-31T04:00:19Z</date.available>
<date.issued>2008</date.issued>
<identifier.citation>Hepatology Research, 2008, v. 38 SUPPL. 1, p. S107-S115</identifier.citation>
<identifier.issn>1386-6346</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/59928</identifier.uri>
<description.abstract>Altered protein and energy metabolism is a hallmark of chronic liver disease, characterized by decreased plasma branched-chain amino acids (BCAA) and increased plasma aromatic amino acids (AAA). Overwhelming evidence has indicated that the incidence of complications of chronic liver disease increases with malnutrition. Hence nutritional management in patients with chronic liver disease must receive high priority. The use of BCAA supplementation has been a controversial subject. This review summarizes published results of BCAA supplementation as a nutritional therapy for patients with cirrhosis and hepatocellular carcinoma (HCC). On balance, it would be appropriate to conclude that BCAA are associated with decreased frequency of complications of cirrhosis and improved nutritional status when prescribed as a maintenance therapy for patients with cirrhosis. More studies are, however, required to identify those who might benefit most from BCAA supplementation. &#169; 2008 The Japan Society of Hepatology.</description.abstract>
<language>eng</language>
<publisher>Blackwell Publishing Ltd</publisher>
<relation.ispartof>Hepatology Research</relation.ispartof>
<rights>Hepatology Research. Copyright &#169; Blackwell Publishing Ltd.</rights>
<subject>Branched-chain amino acids</subject>
<subject>Cirrhosis</subject>
<subject>Hepatic encephalopathy</subject>
<subject>Hepatocellular carcinoma</subject>
<subject>Liver transplantation</subject>
<title>Role of branched-chain amino acids in management of cirrhosis and hepatocellular carcinoma</title>
<type>Conference_Paper</type>
<identifier.openurl>http://library.hku.hk:4550/resserv?sid=HKU:IR&amp;issn=1386-6346&amp;volume=38&amp;issue=Suppl. 1&amp;spage=S107&amp;epage=S115&amp;date=2008&amp;atitle=Role+of+branched-chain+amino+acids+in+management+of+cirrhosis+and+hepatocellular+carcinoma</identifier.openurl>
<description.nature>link_to_subscribed_fulltext</description.nature>
<identifier.doi>10.1111/j.1872-034X.2008.00435.x</identifier.doi>
<identifier.pmid>19125941</identifier.pmid>
<identifier.scopus>eid_2-s2.0-58049084242</identifier.scopus>
<identifier.hkuros>167036</identifier.hkuros>
<relation.references>http://www.scopus.com/mlt/select.url?eid=2-s2.0-58049084242&amp;selection=ref&amp;src=s&amp;origin=recordpage</relation.references>
<identifier.volume>38</identifier.volume>
<identifier.issue>SUPPL. 1</identifier.issue>
<identifier.spage>S107</identifier.spage>
<identifier.epage>S115</identifier.epage>
<identifier.isi>WOS:000261713100019</identifier.isi>
<publisher.place>Ireland</publisher.place>
</item>
Author Affiliations
  1. The University of Hong Kong
  2. University of Sydney