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Article: Proteomic identification of a monoclonal antibody recognizing caveolin-1 in hepatocellular carcinoma with metastatic potential

TitleProteomic identification of a monoclonal antibody recognizing caveolin-1 in hepatocellular carcinoma with metastatic potential
Authors
KeywordsCaveolin-1
Hepatocellular carcinoma
Metastasis
Monoclonal antibody
Issue Date2009
PublisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/ppl/index.htm
Citation
Protein And Peptide Letters, 2009, v. 16 n. 5, p. 479-485 How to Cite?
AbstractA monoclonal antibody, McAb9E (IgG3), was generated against a metastatic HCC cell line, MHCC-1. The antigen was characterized as human Caveolin-1 (Cav-1, 21kDa), with pI of 5.65. The Cav-1 antigen was found significantly over expressed in metastatic HCC cell lines as well as in tumor specimens. The Cav-1 specific McAb may be a useful molecular agent for metastatic HCC. © 2009 Bentham Science Publishers Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/59923
ISSN
2015 Impact Factor: 1.069
2015 SCImago Journal Rankings: 0.472
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHu, MYen_HK
dc.contributor.authorLam, CTen_HK
dc.contributor.authorLiu, KDen_HK
dc.contributor.authorXu, Zen_HK
dc.contributor.authorFatima, Sen_HK
dc.contributor.authorSu, YCFen_HK
dc.contributor.authorTsang, Fen_HK
dc.contributor.authorChen, Jen_HK
dc.contributor.authorPang, JZen_HK
dc.contributor.authorQin, LXen_HK
dc.contributor.authorLuk, JMen_HK
dc.date.accessioned2010-05-31T04:00:14Z-
dc.date.available2010-05-31T04:00:14Z-
dc.date.issued2009en_HK
dc.identifier.citationProtein And Peptide Letters, 2009, v. 16 n. 5, p. 479-485en_HK
dc.identifier.issn0929-8665en_HK
dc.identifier.urihttp://hdl.handle.net/10722/59923-
dc.description.abstractA monoclonal antibody, McAb9E (IgG3), was generated against a metastatic HCC cell line, MHCC-1. The antigen was characterized as human Caveolin-1 (Cav-1, 21kDa), with pI of 5.65. The Cav-1 antigen was found significantly over expressed in metastatic HCC cell lines as well as in tumor specimens. The Cav-1 specific McAb may be a useful molecular agent for metastatic HCC. © 2009 Bentham Science Publishers Ltd.en_HK
dc.languageengen_HK
dc.publisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/ppl/index.htmen_HK
dc.relation.ispartofProtein and Peptide Lettersen_HK
dc.subjectCaveolin-1en_HK
dc.subjectHepatocellular carcinomaen_HK
dc.subjectMetastasisen_HK
dc.subjectMonoclonal antibodyen_HK
dc.titleProteomic identification of a monoclonal antibody recognizing caveolin-1 in hepatocellular carcinoma with metastatic potentialen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0929-8665&volume=&spage=479&epage=485&date=2009&atitle=Proteomic+identification+of+a+monoclonal+antibody+recognizing+caveolin-1+in+hepatocellular+carcinoma+with+metastatic+potential.+en_HK
dc.identifier.emailLuk, JM: jmluk@hkucc.hku.hken_HK
dc.identifier.authorityLuk, JM=rp00349en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.2174/092986609788167743en_HK
dc.identifier.pmid19442226en_HK
dc.identifier.scopuseid_2-s2.0-67649378832en_HK
dc.identifier.hkuros166247en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67649378832&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue5en_HK
dc.identifier.spage479en_HK
dc.identifier.epage485en_HK
dc.identifier.isiWOS:000265799400005-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridHu, MY=7402639252en_HK
dc.identifier.scopusauthoridLam, CT=7402989860en_HK
dc.identifier.scopusauthoridLiu, KD=35277823600en_HK
dc.identifier.scopusauthoridXu, Z=9236444800en_HK
dc.identifier.scopusauthoridFatima, S=8437472300en_HK
dc.identifier.scopusauthoridSu, YCF=7404456219en_HK
dc.identifier.scopusauthoridTsang, F=36895782100en_HK
dc.identifier.scopusauthoridChen, J=35291294100en_HK
dc.identifier.scopusauthoridPang, JZ=14421354300en_HK
dc.identifier.scopusauthoridQin, LX=16747601200en_HK
dc.identifier.scopusauthoridLuk, JM=7006777791en_HK
dc.identifier.citeulike4447215-

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