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Article: Impact of prenatal diagnosis on choledochal cysts and the benefits of early excision

TitleImpact of prenatal diagnosis on choledochal cysts and the benefits of early excision
Authors
KeywordsCholedochal cyst
Outcome
Prenatal diagnosis
Issue Date2009
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JPC
Citation
Journal Of Paediatrics And Child Health, 2009, v. 45 n. 1-2, p. 28-30 How to Cite?
AbstractAim:To evaluate the clinical outcomes of patients with prenatally diagnosed choledochal cysts compared with those diagnosed after birth and the optimal timing of definitive treatment. Methods: Retrospective review of all patients who underwent primary choledochal cyst excision and Roux-en-Y hepaticojejunostomy from 1996 to 2006 at a single institution. Results: A total of 45 patients were included. Ten (22.2%) of the patients had prior prenatal diagnosis. The mean age at operation for this group was 4.4 months and mean follow up was 55.9 months. There was no operative complication or late morbidity. For the post-natal diagnosis group, the mean age at operation was 5.7 years (P < 0.000) and mean follow up period was 69 months. The most common presentation in this group was abdominal pain (31.4%), followed by pancreatitis (28.6%) and symptoms of cholestasis (25.7%). Early post-operative morbidities occurred in two (5.7%) patients. On long-term follow up, two (5.7%) further patients in the post-natal group developed complications. Conclusion: Prenatal diagnosis of choledochal cysts results in earlier definitive surgery. More adverse complications were seen in those who had surgery at an older age. We therefore recommend early excision of choledochal cysts. © 2008 Paediatrics and Child Health Division (Royal Australasian College of Physicians).
Persistent Identifierhttp://hdl.handle.net/10722/59895
ISSN
2015 Impact Factor: 1.477
2015 SCImago Journal Rankings: 0.692
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorFoo, DCCen_HK
dc.contributor.authorWong, KKYen_HK
dc.contributor.authorLan, LCLen_HK
dc.contributor.authorTam, PKHen_HK
dc.date.accessioned2010-05-31T03:59:39Z-
dc.date.available2010-05-31T03:59:39Z-
dc.date.issued2009en_HK
dc.identifier.citationJournal Of Paediatrics And Child Health, 2009, v. 45 n. 1-2, p. 28-30en_HK
dc.identifier.issn1034-4810en_HK
dc.identifier.urihttp://hdl.handle.net/10722/59895-
dc.description.abstractAim:To evaluate the clinical outcomes of patients with prenatally diagnosed choledochal cysts compared with those diagnosed after birth and the optimal timing of definitive treatment. Methods: Retrospective review of all patients who underwent primary choledochal cyst excision and Roux-en-Y hepaticojejunostomy from 1996 to 2006 at a single institution. Results: A total of 45 patients were included. Ten (22.2%) of the patients had prior prenatal diagnosis. The mean age at operation for this group was 4.4 months and mean follow up was 55.9 months. There was no operative complication or late morbidity. For the post-natal diagnosis group, the mean age at operation was 5.7 years (P < 0.000) and mean follow up period was 69 months. The most common presentation in this group was abdominal pain (31.4%), followed by pancreatitis (28.6%) and symptoms of cholestasis (25.7%). Early post-operative morbidities occurred in two (5.7%) patients. On long-term follow up, two (5.7%) further patients in the post-natal group developed complications. Conclusion: Prenatal diagnosis of choledochal cysts results in earlier definitive surgery. More adverse complications were seen in those who had surgery at an older age. We therefore recommend early excision of choledochal cysts. © 2008 Paediatrics and Child Health Division (Royal Australasian College of Physicians).en_HK
dc.languageengen_HK
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JPCen_HK
dc.relation.ispartofJournal of Paediatrics and Child Healthen_HK
dc.subjectCholedochal cysten_HK
dc.subjectOutcomeen_HK
dc.subjectPrenatal diagnosisen_HK
dc.titleImpact of prenatal diagnosis on choledochal cysts and the benefits of early excisionen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1034-4810&volume=45&spage=28&epage=30&date=2009&atitle=Impact+of+prenatal+diagnosis+on+choledochal+cysts+and+the+benefits+of+early+excisionen_HK
dc.identifier.emailWong, KKY: kkywong@hkucc.hku.hken_HK
dc.identifier.emailTam, PKH: paultam@hkucc.hku.hken_HK
dc.identifier.authorityWong, KKY=rp01392en_HK
dc.identifier.authorityTam, PKH=rp00060en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1440-1754.2008.01424.xen_HK
dc.identifier.pmid19208062-
dc.identifier.scopuseid_2-s2.0-58649112396en_HK
dc.identifier.hkuros154823en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58649112396&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume45en_HK
dc.identifier.issue1-2en_HK
dc.identifier.spage28en_HK
dc.identifier.epage30en_HK
dc.identifier.isiWOS:000262644400007-
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridFoo, DCC=26021803000en_HK
dc.identifier.scopusauthoridWong, KKY=24438686400en_HK
dc.identifier.scopusauthoridLan, LCL=7005687228en_HK
dc.identifier.scopusauthoridTam, PKH=7202539421en_HK
dc.identifier.citeulike3939683-

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